Zobrazeno 1 - 5
of 5
pro vyhledávání: '"M. V. Velikopol'skaya"'
Autor:
A. A. Spasov, A. F. Kucheryavenko, K. A. Gaidukova, V. S. Sirotenko, L. A. Smirnova, A. F. Ryabukha, K. A. Kuznetsov, M. V. Velikopol’skaya
Publikováno v:
Pharmaceutical Chemistry Journal. 56:1024-1026
Autor:
Alexander A. Spasov, A. F. Ryabukha, K. A. Kuznetsov, M. V. Velikopol’skaya, D. S. Yakovlev, L. A. Smirnova
Publikováno v:
Pharmaceutical Chemistry Journal. 55:312-314
A quantitative determination method for drug substance RU-31, a derivative of a methoxyphenylimidazo - [1,2-α]benzimidazole possessing antimigraine activity, in biological samples was developed. This method has selectivity and high sensitivity suffi
Autor:
D. S. Yakovlev, Alexander A. Spasov, K. A. Kuznetsov, M. V. Velikopol’skaya, A. F. Ryabukha, L. A. Smirnova
Publikováno v:
Pharmaceutical Chemistry Journal.
The bioequivalence of the tablet dosage form of RU-31 substance was studied. The main pharmacokinetic parameters were determined. The actual relative bioequivalence index was calculated and turned out to be ~100%. RU-31 from tablets did not accumulat
Autor:
V. N. Perfilova, Ivan N. Tyurenkov, A. F. Ryabukha, O. S. Vasil’eva, L. A. Smirnova, L. M. Ganicheva, K. A. Kuznetsov, M. V. Velikopol’skaya
Publikováno v:
Pharmaceutical Chemistry Journal. 53:1090-1092
An HPLC method for quantitative determination of the new biologically active GABA derivative Solifen was developed. The method sensitivity, compound retention time and UV absorption maximum were determined. The optimum extractant for the compound fro
Autor:
E. A. Suchkov, K. A. Kuznetsov, M. V. Velikopol’skaya, A. F. Ryabukha, D. A. Bakulin, Ivan N. Tyurenkov, L. A. Smirnova, É. F. Stepanova, A. M. Shevchenko
Publikováno v:
Pharmaceutical Chemistry Journal. 52:495-496
The bioequivalence of mefebut drug substance and its tablet dosage form was investigated by studying the main pharmacokinetic parameters and calculating the relative bioavailability. The results showed that mefebut circulated for up to 4 h in rabbit