Zobrazeno 1 - 10
of 12
pro vyhledávání: '"M. V. Sauganth Paul"'
Autor:
R. Harikumaran Nair, Kozhiparambil Gopalan Raghu, M. V. Sauganth Paul, Mathews V. Varghese, A Prathapan, M. Abhilash, Manju Alex
Publikováno v:
Redox Report. 22:346-352
Objectives: Arsenic trioxide (As(2)O(3)) is a potent drug for acute promyelocytic leukaemia, but its clinical trials are allied with some serious adverse events mainly cardiac functional abnormalities. So the objective of our investigation is to iden
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8bfef73e94736e52d4ad729814524626
https://doi.org/10.1080/13510002.2017.1289313
https://doi.org/10.1080/13510002.2017.1289313
Publikováno v:
Comparative Clinical Pathology. 24:927-933
Aspartame is one of the most widely used artificial sweeteners globally. Data concerning acute toxicity of aspartame is controversial, and knowledge on its chronic effect is limited. The present study evaluates the effect of long-term intake of aspar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f3b6bb62233835dbbf35efee54824b97
https://doi.org/10.1007/s00580-014-2013-8
https://doi.org/10.1007/s00580-014-2013-8
Publikováno v:
IOSR Journal of Pharmacy and Biological Sciences. 7:42-47
Nephrolithiasis is one of the most common and painful of urological disorders with a high prevalence rate. The role of calcium oxalate crystals, which are the predominant component of kidney stones in generating oxidative stress, have been clearly de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3ce8c34df02f1453755e8d683340248f
https://doi.org/10.9790/3008-0714247
https://doi.org/10.9790/3008-0714247
Publikováno v:
Cardiovascular toxicology. 17(2)
Arsenic trioxide (As2O3) is a highly effective therapeutic against acute promyelocytic leukaemia, but its clinical efficacy is burdened by serious cardiac toxicity. The present study was performed to evaluate the effect of omega (ω)-3 fatty acid on
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c275926f4312effab8f4b2bba72290c3
https://pubmed.ncbi.nlm.nih.gov/26886836
https://pubmed.ncbi.nlm.nih.gov/26886836
Autor:
Alex Manju, S Abhilash, M. Abhilash, M. V. Sauganth Paul, R. Harikumaran Nair, Varghese V. Mathews
Publikováno v:
Toxicology and Industrial Health. 30:806-813
Arsenic trioxide (As2O3) is an effective drug in the treatment of leukaemia and many solid tumours. In clinical trials, arsenic therapy is closely associated with hepatic toxicity. The present study was designed to investigate the efficacy of omega-3
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31b6f24bafb86f5eb3e0b8352c6037ac
https://doi.org/10.1177/0748233712463778
https://doi.org/10.1177/0748233712463778
Autor:
M. V. Sauganth Paul, Varghese V. Mathews, R. Harikumaran Nair, Alex Manju, M. Abhilash, Prakash Binu
Publikováno v:
Asian Pacific Journal of Tropical Biomedicine. 2:S706-S711
Objective To evaluate the efficacy of curcumin in combating arsenic induced hepatic oxidative stress, histopathological changes and the hepatic arsenic accumulation in rat model. Methods Oxidative stress was induced by oral administration 4 mg/kg b.w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2e28b50248cbb44a6bc9c25f4757cef1
https://doi.org/10.1016/s2221-1691(12)60300-1
https://doi.org/10.1016/s2221-1691(12)60300-1
Publikováno v:
Food and Chemical Toxicology. 49:1203-1207
The present study evaluates the effect of long term intake of aspartame, the artificial sweetener, on liver antioxidant system and hepatocellular injury in animal model. Eighteen adult male Wistar rats, weighing 150-175 g, were randomly divided into
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6db62192b5b80a6ce54ff55982a292a4
https://doi.org/10.1016/j.fct.2011.02.019
https://doi.org/10.1016/j.fct.2011.02.019
Autor:
Manju, Alex, M V, Sauganth Paul, M, Abhilash, Varghese V, Mathews, T V, Anilkumar, R Harikumaran, Nair
Publikováno v:
BJU international. 114(3)
To evaluate the effect of astaxanthin on renal angiotensin-I converting enzyme (ACE) levels, osteopontin (OPN) and transforming growth factor β1 (TGF-β1) expressions and the extent of crystal deposition in experimentally induced calcium oxalate kid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a56a64fb137d1552cf009b150ae586c4
https://pubmed.ncbi.nlm.nih.gov/24712822
https://pubmed.ncbi.nlm.nih.gov/24712822
Autor:
R. Harikumaran Nair, Manju Alex, T.V. Anilkumar, Varghese V. Mathews, M. Abhilash, M. V. Sauganth Paul
Publikováno v:
BJU International.
Objectives To evaluate the effect of astaxanthin on renal angiotensin-I converting enzyme (ACE) levels, osteopontin (OPN) and transforming growth factor β1 (TGF-β1) expressions and the extent of crystal deposition in experimentally induced calcium
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b4881a983fa092a1a440d0af273e7ed6
https://doi.org/10.1111/bju.12537
https://doi.org/10.1111/bju.12537
Publikováno v:
Toxicology mechanisms and methods. 22(8)
Chronic oral intake of high doses of monosodium glutamate (MSG) could be harmful to tissues and organs. Oxidative stress enhances membrane damage by lipid peroxidation and alterations of antioxidant enzymes, which affects the functional activity of o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2467e8f68f7a73f455ede57eb033eb9d
https://pubmed.ncbi.nlm.nih.gov/22827614
https://pubmed.ncbi.nlm.nih.gov/22827614