Zobrazeno 1 - 10
of 28
pro vyhledávání: '"M. V. SEFTON"'
Publikováno v:
Journal of Materials Science: Materials in Medicine. 5:622-627
The interaction between blood and an artificial surface results in the activation of complement and can lead to extensive inflammatory reactions. In vitro work was undertaken to validate a system of assays to evaluate the complement activation of a c
Autor:
S, Lahooti, M V, Sefton
Publikováno v:
Methods in molecular medicine. 18
Encapsulation of cells in a membrane prior to implantation holds potential for controlling the adverse immune response that may be generated against the transplanted cells, by physically isolating the cells from the host's immune system. If successfu
Autor:
P. K. WATLER, M. V. SEFTON
Publikováno v:
ASAIO Transactions. 36:70-77
Publikováno v:
Journal of biomedical materials research. 55(4)
With some exceptions, surface chemistry had little effect on platelet and leukocyte activation, and cell deposition, by scanning electron microscopy after blood exposure and clotting times among a group of 12 unmodified and plasma modified tubings. A
Publikováno v:
Journal of biomedical materials research. 46(3)
Polyacrylate films in the absence of added endotoxin caused rat peritoneal macrophages to secrete a small amount of TNFalpha. There was little difference, if any, among the materials, which included various co- or ter-polymers of hydroxyethyl methacr
Publikováno v:
Journal of biomedical materials research. 44(3)
Neutrophil activation for adherent and nonadherent cells, as measured by flow cytometry, was not strongly dependent on material surface chemistry. We had hypothesized that material-induced neutrophil activation was an important parameter associated w
Autor:
M V, Sefton, K A, Woodhouse
Publikováno v:
Journal of cutaneous medicine and surgery. 3
Wound care has become one of the first fields to see the benefit of a new technology: tissue engineering. Tissue engineering involves the development of new materials or devices capable of specific interactions with biological tissues. In wound care,
Publikováno v:
Journal of biomedical materials research. 37(2)
Assessment of material-induced platelet activation is important given that it is thought to be a major mechanism of biomaterials thrombogenicity. We monitored, by flow cytometry, platelet microparticle (MP) levels in the circulation during the connec
Publikováno v:
Journal of biomedical materials research. 32(2)
Commercial samples of atactic polypropylene (aPP) and polyvinyl methyl ether (PVME) were purified and spin-cast onto glass coverslips with a view to using these as model surfaces in thrombogenicity studies. These materials differ from polyvinyl alcoh
Publikováno v:
Journal of biomedical materials research. 32(1)
Material-induced thrombogenicity is in part a consequence of leukocyte activation. To evaluate and compare material-induced platelet damage, we have expanded our in vitro flow cytometric immunoassay to include assessment of leukocyte activation. We h