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The effect of TGF-β1 polymorphisms on pulmonary disease progression in patients with cystic fibrosis
Autor:
T. Trojan, Miguel A. Alejandre Alcazar, G. Fink, J. C. Thomassen, M. V. Maessenhausen, E. Rietschel, P. M. Schneider, S. van Koningsbruggen-Rietschel
Publikováno v:
BMC Pulmonary Medicine, Vol 22, Iss 1, Pp 1-10 (2022)
Abstract Background Transforming Growth Factor-β1 (TGF-β1) is a genetic modifier in patients with cystic fibrosis (CF). Several single nucleotide polymorphisms (SNPs) of TGF-β1 are associated with neutrophilic inflammation, lung fibrosis and loss
Externí odkaz:
https://doaj.org/article/9ba70f7b30c54d429cc248a3a0b2674d