Zobrazeno 1 - 10
of 22
pro vyhledávání: '"M. V. Khrapova"'
Publikováno v:
Сибирский научный медицинский журнал, Vol 43, Iss 5, Pp 127-134 (2023)
TS-13 (sodium 3-(3’-tert-butyl-4’-hydroxyphenyl)propylthiosulfonate) is a synthetic antioxidant that has demonstrated biological effectiveness in numerous studies in modeling pathological conditions in vivo, in particular, in the model of Parkins
Externí odkaz:
https://doaj.org/article/ac9214d960014da384b5aac1afa2b216
Autor:
P. M. Kozhin, A. S. Sementsov, S. E. Khrapov, M. V. Khrapova, L. P. Romakh, N. V. Kandalintseva, E. B. Menshchikova
Publikováno v:
Сибирский научный медицинский журнал, Vol 42, Iss 6, Pp 35-44 (2022)
Oxidative stress is an important mechanism of myocardial damage during ischemia/reperfusion. To investigate the possibility of restoring the redox balance using “indirect” antioxidant effects, the cardioprotective effect Keap1/Nrf2/ ARE system in
Externí odkaz:
https://doaj.org/article/35454f24c9b044708ecf9413609656c3
Autor:
M. V. Khrapova, S. E. Khrapov, A. V. Chechushkov, P. M. Kozhin, L. P. Romakh, A. E. Serykh, S. V. Kholshin, N. V. Kandalintseva, E. B. Menshchikova
Publikováno v:
Сибирский научный медицинский журнал, Vol 42, Iss 5, Pp 11-18 (2022)
One of the promising areas of modern pharmacology is the development of «indirect antioxidants» capable of activating redox-sensitive signaling systems, primarily the Keap1/Nrf2/ARE system. Among its chemical inductors is the hydrophilic monosubsti
Externí odkaz:
https://doaj.org/article/64f0c7ef199e4899abed2cc09b3ca94e
Autor:
S. E. Khrapov, P. M. Kozhin, M. V. Khrapova, A. E. Serykh, L. P. Romakh, V. S. Pavlov, A. V. Chechushkov, S. V. Kholshin, N. K. Zenkov, E. B. Menshchikova
Publikováno v:
Сибирский научный медицинский журнал, Vol 41, Iss 3, Pp 25-31 (2021)
Under certain conditions, both activators and inhibitors of Nrf2-dependent signaling and autophagy can serve as potential agents for the prevention, treatment, and maintenance therapy of cancer, as well as overcoming chemoresistance. We are developin
Externí odkaz:
https://doaj.org/article/b5fda36ed7084758af04b032e864aa8b
Autor:
E. B. Menshchikova, N. K. Zenkov, P. M. Kozhin, A. V. Chechushkov, V. S. Pavlov, L. P. Romakh, M. V. Khrapova, A. E. Serykh, O. B. Gritsyk, N. V. Kandalintseva
Publikováno v:
Сибирский научный медицинский журнал, Vol 40, Iss 6, Pp 58-69 (2020)
Understanding the role of reactive oxygen and nitrogen species in eustress (redox balance) and distress (oxidative stress) development poses new challenges for biomedical scientists and pharmacologists in the search for compounds that can not only ha
Externí odkaz:
https://doaj.org/article/d474da70577948f88ecfc58d526ab64c
Autor:
P. M. Kozhin, A. V. Chechushkov, N. S. Zaytseva, M. V. Khrapova, L. A. Cherdantseva, E. B. Menshchikova, A. V. Troitsky, V. A. Shkurupy
Publikováno v:
Сибирский научный медицинский журнал, Vol 39, Iss 4, Pp 22-29 (2019)
The study analyzes the expression of protein genes involved in intracellular signaling pathways associated with a profibrotic response, activation of epithelial-mesenchymal and endothelial-mesenchymal transitions, in modeling tuberculous granulomatos
Externí odkaz:
https://doaj.org/article/842a758e71d946fd996780b105c1304d
Autor:
M. V. Khrapova, M. I. Dushkin
Publikováno v:
Атеросклероз, Vol 7, Iss 2, Pp 23-43 (2011)
Some aspects of peroxisome proliferator activated receptors (PPAR) involvement in regulation of stress-dependent biological processes leading to insulin resistance, lipid imbalance, hypertension and inflammation are reviewed. Analysis of literature d
Externí odkaz:
https://doaj.org/article/65ba2321504d43449196030693f0884b
Publikováno v:
Neuroscience and Behavioral Physiology. 48:488-495
We report here a comparative analysis of the acquisition of a conditioned passive avoidance reaction in mice of the mutant strains DISC1-Q31L and DISC1-L100P and mice of the control strain C57Bl/6NCr1 and detection of the effects of gender and age on
Autor:
N. K. Zenkov, Andrey Sementsov, M. V. Khrapova, Peter Kozhin, A. V. Chechushkov, Leonid Maslov, S.E. Khrapov, E. B. Menshchikova, N. V. Kandalintseva
Publikováno v:
Free Radical Biology and Medicine. 159:S93
Autor:
A. V. Chechushkov, N. V. Kandalintseva, N. K. Zenkov, E. B. Menshchikova, P. M. Kozhin, M. V. Khrapova, A. V. Kovner, G. G. Martinovich
Publikováno v:
Bulletin of experimental biology and medicine. 166(5)
ROS are important intracellular messengers; their ambiguous role in malignant processes was demonstrated in many studies. The effects of a synthetic phenolic antioxidant sodium 3-(3’-tert-butyl-4’-hydroxyphenyl)propyl thiosulfonate sodium (TS-13)