The intracellular lifestyle of an archaeal symbiont

Autor: Joshua N. Hamm, Yan Liao, Andriko von Kügelgen, Nina Dombrowski, Evan Landers, Christopher Brownlee, Emma M. V. Johansson, Renee M. Whan, Matthew A. B. Baker, Buzz Baum, Tanmay A. M. Bharat, Iain G. Duggin, Anja Spang, Ricardo Cavicchioli

SUMMARYDPANNArchaeaare a diverse archaeal clade characterised by small cells and reduced genomes. To date, all cultivated DPANNArchaeaare ectosymbionts that require direct cell-cell interactions with a host archaeal species for proliferation. However

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::85d30958d86a209524a9ec98b29b7233
https://doi.org/10.1101/2023.02.24.529834

Single cell genotyping of matched bone marrow and peripheral blood cells in treatment naive and AZA-treated MDS and CMML

Autor: Annatina Schnegg-Kaufmann, Julie A. I. Thoms, Golam Sarower Bhuyan, Henry R. Hampton, Lachlin Vaughan, Kayleigh Rutherford, Purvi M. Kakadia, Emma M. V. Johansson, Tim Failes, Greg M. Arndt, Jason Koval, Robert Lindeman, Pauline Warburton, Alba Rodriguez-Meira, Adam J. Mead, Ashwin Unnikrishnan, Stefan K. Bohlander, Elli Papaemmanuil, Omid Faridani, Christopher J. Jolly, Fabio Zanini, John E. Pimanda

Progressively acquired somatic mutations in hematopoietic stem cells are central to pathogenesis in myelodysplastic syndromes (MDS) and chronic myelomonocytic leukemia (CMML). They can lead to proliferative advantages, impaired differentiation and pr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::fbcc319bfd3ab113a7e7e2f88732a8b8
https://doi.org/10.1101/2022.01.20.476890

Biocompatible Polymer Nanoparticles for Intra-cellular Applications

Autor: Emma M. V. Johansson, Mark Bradley

Publikováno v: CHIMIA, Vol 66, Iss 4 (2012)

Polymeric styrene microspheres have a great potential at the interface of chemistry and biology. The progress of the synthetic development of multifunctional microspheres and their use as delivery agents of different biomolecules into cells is discus

Externí odkaz: https://doaj.org/article/334e1e9d02c84617bdaf492320e8be11

Palladium-mediated bioorthogonal conjugation of dual-functionalised nanoparticles and their cellular delivery

Autor: Frank Thielbeer, Neil Norouzi, Emma M. V. Johansson, Sunay V. Chankeshwara, Mark Bradley

Publikováno v: Chem. Sci.. 4:425-431

Nanoparticles have gained considerable significance in the life sciences due to their ability to be internalised by living cells and the relative ease with which they can be functionalised with cargos ranging from molecular sensors to biomacromolecul

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::abf78592570a4f563ffcd7a8f1c9b60e
https://doi.org/10.1039/c2sc20706k

Flow and Microwave-Assisted Synthesis of N-(Triethylene glycol)glycine Oligomers and Their Remarkable Cellular Transporter Activities

Autor: Ana M. Pérez-López, Mark Bradley, Emma M. V. Johansson, ThingSoon Jong, Annamaria Lilienkampf

Publikováno v: Jong, T, Pérez-López, A M, Johansson, E M V, Lilienkampf, A & Bradley, M 2015, ' Flow and Microwave-Assisted Synthesis of N-(Triethylene glycol)glycine Oligomers and Their Remarkable Cellular Transporter Activities ', Bioconjugate chemistry . https://doi.org/10.1021/acs.bioconjchem.5b00307

Peptidomimetics, such as oligo-N-alkylglycines (peptoids), are attractive alternatives to traditional cationic cell-penetrating peptides (such as R9) due to their robust proteolytic stability and reduced cellular toxicity. Here, monomeric N-alkylglyc

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4c70d3b7f9a015e0adf69259d92ca79
https://pubmed.ncbi.nlm.nih.gov/26155805