Zobrazeno 1 - 10
of 27
pro vyhledávání: '"M. V. Gudkova"'
Autor:
D. V. Sorokin, O. E. Andreeva, A. M. Scherbakov, D. I. Salnikova, M. V. Gudkova, M. A. Krasil’nikov
Publikováno v:
Успехи молекулярной онкологии, Vol 10, Iss 4, Pp 108-115 (2023)
Introduction. The study of the effect of irradiation or any other DNA-damaging agents on the sensitivity of tumors to conservative therapy, drug or hormonal, is among the most imporant tasks that determine the efficiency of combined therapy of cancer
Externí odkaz:
https://doaj.org/article/e5ff026858854d6c913023acd0a998d1
Autor:
Yu. Yu. Shchegolev, M. A. Karpukhina, D. V. Sorokin, A. M. Scherbakov, O. E. Andreeva, V. E. Razuvaeva, T. A. Bogush, I. N. Mikhaylova, L. V. Demidov, M. V. Gudkova, M. A. Krasil’nikov
Publikováno v:
Успехи молекулярной онкологии, Vol 10, Iss 3, Pp 50-58 (2023)
Introduction. Melanoma belongs to the group of the most malignant tumors characterized by aggressive growth and active metastasis. At the same time, the effectiveness of therapy, primarily targeted therapy, is largely limited by the rapid development
Externí odkaz:
https://doaj.org/article/94aa493afae74c17a55cd214163d9cbc
Autor:
O. E. Andreeva, D. V. Sorokin, A. M. Scherbakov, Y. Y. Shchegolev, M. V. Gudkova, M. A. Krasil’nikov
Publikováno v:
Успехи молекулярной онкологии, Vol 9, Iss 4 (2022)
The development of acquired resistance of malignant tumors to specific drugs, such as target and hormonal drugs, is usually associated with a rearrangement of the intracellular signaling network and activation of unblocked growth pathways. Epigenetic
Externí odkaz:
https://doaj.org/article/b6b9b81ad4244a4f8a53cec0c8e60feb
Autor:
D. V. Sorokin, O. E. Andreeva, E. I. Mikhaevich, Yu. Yu. Shchegolev, A. M. Scherbakov, M. V. Gudkova, M. A. Krasil’nikov
Publikováno v:
Успехи молекулярной онкологии, Vol 7, Iss 3, Pp 58-62 (2020)
The most effective treatment of the hormone-dependent breast cancer is based on the antiestrogens SERM and aromatase inhibitor treatment, however its efficiency is limited by the acquired resistance to the drugs.Previously we have revealed the effect
Externí odkaz:
https://doaj.org/article/a85876f2fe654ccc96ea9c4033542666
Publikováno v:
Bulletin of Experimental Biology and Medicine. 161:837-840
Using the autoradiographic method, we studied the kinetics of DNA synthesis over the mitotic cycle in mouse corneal epithelium cells in delayed periods after γ-irradiation in different points of the S phase of the first mitotic cycle. The index labe
Publikováno v:
Bulletin of Experimental Biology and Medicine. 161:193-196
We proposed a new model of supramolecular DNA structure. Similar to the previously developed by us model of primary DNA structure [11-15], 3D structure of DNA molecule is assembled in accordance to a mathematic rule known as Fibonacci sequence. Unlik
Publikováno v:
Bulletin of experimental biology and medicine. 165(1)
Within the framework of the previously proposed model of structural organization of DNA that supplements the Watson-Crick model and is based on a mathematical regulation - Fibonacci sequence, we suppose the existence of nucleotides without nitrogenou
Publikováno v:
Bulletin of Experimental Biology and Medicine. 159:572-575
Kinetics of DNA synthesis throughout the mitotic cycle in mouse corneal epithelial cells after single γ-irradiation of cells (4 Gy) at the end of S phase was studied by the method of radioautography. It was found that single irradiation increased th
Publikováno v:
Bulletin of Experimental Biology and Medicine. 157:496-500
Using the autoradiographic method we studied the kinetics of DNA synthesis during themitotic cycle of mouse corneal epithelial cells after γ-irradiation in a dose of 2 Gy at different S-phase points. Normally, S phase in corneal epitheliocytes inclu
Publikováno v:
Bulletin of Experimental Biology and Medicine. 156:260-265
The kinetics of DNA synthesis in the mitotic cycle of mouse corneal epithelial cells was studied after a single γ-irradiation of cells in a dose of 4 Gy at different S-phase points. Normally, corneal epitheliocyte S phase consists of S1 and S2 phase