Zobrazeno 1 - 10
of 21
pro vyhledávání: '"M. V. Dumina"'
Autor:
M. A. Eldarov, M. V. Dumina, A. A. Zhgun, D. D. Zhdanov, M. V. Pokrovskay, Nikolay N. Sokolov, S. S. Aleksandrova
Publikováno v:
Applied Biochemistry and Microbiology. 57:594-602
The activity of novel uncharacterized extremophilic L-asparaginases from the psychrophilic fungi Sclerotinia borealis, the thermoacidophilic crenarchea Acidilobus saccharovorans, and the thermophilic bacteria Melioribacter roseus were studied. Active
Publikováno v:
Biomeditsinskaya Khimiya. 66:105-123
L-asparaginase is extensively used in the treatment of acute lymphoblastic leukemia and several other lymphoproliferative diseases. In addition to its biomedical application, L-asparaginase is also of prospective use in food industry to reduce the fo
Autor:
A. A. Zhgun, Nikolay N. Sokolov, M. V. Pokrovskaya, Dmitry D. Zhdanov, S. S. Aleksandrova, M. V. Dumina, Michael A. Eldarov
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 9894, p 9894 (2021)
International Journal of Molecular Sciences
Volume 22
Issue 18
International Journal of Molecular Sciences
Volume 22
Issue 18
L-asparaginase (L-ASNase) is a vital enzyme with a broad range of applications in medicine and food industry. Drawbacks of current commercial L-ASNases stimulate the search for better-producing sources of the enzyme, and extremophiles are especially
Publikováno v:
Applied Biochemistry and Microbiology. 55:243-254
The filamentous fungus Aspergillus terreus is the main industrial producer of lovastatin, a cholesterol-lowering drug that is also used as a semiproduct for simvastatin production. The exogenous addition of such polyamines as 1,3-diaminopropane or sp
Publikováno v:
Applied Biochemistry and Microbiology. 54:188-197
The expression of two key genes of lovastatin (LOV) biosynthesis has been studied in two Aspergillus terreus strains characterized by a more than hundredfold difference in the LOV yield. As compared to the wild-type strain ATCC 20542, in the overprod
Autor:
Nikolai V. Ravin, M. A. Eldarov, M. V. Dumina, Andrey V. Mardanov, S. A. Kishkovskaia, Tatiana N. Tanashchuk
Publikováno v:
Applied Biochemistry and Microbiology. 53:359-367
Sixteen flor yeast strains from the Magarach Collection of the Microorganisms for Winemaking (Yalta, Crimea), which are used for production of sherry, were analyzed for morphophysiological, cultural, and biochemical properties. Long-term storage did
Publikováno v:
Journal of Bioscience and Bioengineering. 119:52-56
Inorganic polyphosphate performs many regulatory functions in living cells. The yeast exopolyphosphatase PPN1 is an enzyme with multiple cellular localization and probably variable functions. The Saccharomyces cerevisiae strain with overexpressed PPN
Autor:
M. V. Dumina, A. G. Domracheva, M. I. Novak, Dmitry A. Knorre, A. A. Zhgun, A. Ya. Valiachmetov, Fedor F. Severin, Michael A. Eldarov, I. V. Kerpichnikov, Yu. E. Bartoshevich
Publikováno v:
Applied Biochemistry and Microbiology. 49:368-377
Vectors for the expression of MFS transporter CefT of Acremonium chrysogenum—a producer of beta-lactam antibiotic cephalosporin C—and in Saccharomyces cerevisiae as a fusion with the cyan fluorescent protein (CFP) have been generated. The subcell
Autor:
A. A. Zhgun, A. G. Domracheva, Bartoshevich IuE, M. A. Eldarov, M. V. Dumina, Dmitry A. Knorre, Valiakhmetov AIa, M. I. Novak, Kerpichnikov, Fedor F. Severin
Publikováno v:
Прикладная биохимия и микробиология. 49:372-381
Vectors for the expression of the CefT transporter of the MFS family in Acremonium chrysogenum--a producer of beta-lactam antibiotic cephalosporin C--and in Saccharomyces cerevisiae as a fusion with the cyan fluorescent protein (CFP) have been create
Publikováno v:
Russian Journal of Genetics. 48:778-784
Using pulse electrophoresis in controlled homogenous electric field we conducted molecular karyotyping of highly-productive and laboratory strains of Acremonium chrysogenum generating antibiotic cephalosporin C (cefC). Differences in size of several