Zobrazeno 1 - 10
of 30
pro vyhledávání: '"M. V. Berridge"'
Publikováno v:
Apoptosis : an international journal on programmed cell death. 4(2)
Growth factors promote cell survival and proliferation. Homeostasis is maintained by programmed cell death which occurs when the growth stimulus is withdrawn, in response to negative growth regulators such as interferons, TNF-alpha and CD95 ligand, o
Publikováno v:
Anti-cancer drug design. 16(2-3)
A novel secondary sponge metabolite, peloruside A (peloruside), isolated from the marine sponge Mycale sp. (New Zealand), was tested for its cytotoxic effects on mammalian cells in culture. The macrolide structure of peloruside is similar to that of
Publikováno v:
Apoptosis : an international journal on programmed cell death. 6(3)
The marine sponge metabolites mycalamide A (mycalamide) and pateamine are extremely cytotoxic. While mycalamide has been shown to inhibit protein synthesis, the mechanism by which these compounds induce cell death is unknown. Using DNA laddering, Ann
Publikováno v:
Blood. 91(2)
Activation of human peripheral blood neutrophils by pathogens or by phorbol myristate acetate (PMA), fMLP, or myeloid growth factors generates a respiratory burst in which superoxide production plays an important role in killing invading microorganis
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 156(11)
Treatment of activated human T cells with CD95 (Fas/Apo-1) ligand or Abs against CD95 results in apoptotic cell death. Although cellular responses to CD95 ligation have been described in some detail, the early molecular events that result in T cell d
Publikováno v:
Experimental hematology. 21(2)
Hemopoietic growth factors promote cell survival, proliferation and differentiation, but whether these processes, which often occur in concert, are mediated through the same or different receptor signaling mechanisms is not known. Using the bone marr
Autor:
S J Ralph, M V Berridge
Publikováno v:
The Journal of Immunology. 132:2510-2514
A panel of monoclonal antibodies has been used to investigate the presence of antigens of the 'T200' family of cell surface glycoproteins on hemopoietic stem cells. As measured by spleen colony inhibition using CBA bone marrow, stem cells were shown
Autor:
M V Berridge, N Okech
Publikováno v:
The Journal of Immunology. 124:732-738
Publikováno v:
Blood. 72:970-977
The contention that erythropoietin (Epo) affects platelet production was investigated in the rat with recombinant human Epo (rHuEpo). In normal rats, Epo caused a dose-dependent increase in both reticulocyte and platelet numbers, the reticulocyte res