When one size does not fit all: Reconsidering PCOS etiology, diagnosis, clinical subgroups, and subgroup-specific treatments

Autor: V. Unfer, E. Kandaraki, L. Pkhaladze, S. Roseff, M.H. Vazquez-Levin, A.S. Laganà, C. Shiao-Yng, M.I.M. Yap-Garcia, N.D.E. Greene, C.O. Soulage, A. Bevilacqua, S. Benvenga, D. Barbaro, B. Pintaudi, A. Wdowiak, C. Aragona, Z. Kamenov, M. Appetecchia, G. Porcaro, I. Hernandez Marin, F. Facchinetti, T. Chiu, O. Pustotina, O. Papalou, M. Nordio, T. Cantelmi, P. Cavalli, I. Vucenik, R. D'Anna, V.R. Unfer, S. Dinicola, S. Salehpour, A. Stringaro, M. Montaninno Oliva, M. Tugushev, N. Prapas, M. Bizzarri, M.S.B. Espinola, C. Di Lorenzo, A.C. Ozay, J. Nestler

Publikováno v: Endocrine and Metabolic Science, Vol 14, Iss , Pp 100159- (2024)

Polycystic Ovary Syndrome (PCOS) is a complex endocrine disorder that affects a large proportion of women. Due to its heterogeneity, the best diagnostic strategy has been a matter of contention. Since 1990 scientific societies in the field of human r

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d-Chiro-Inositol in Clinical Practice: A Perspective from the Experts Group on Inositol in Basic and Clinical Research (EGOI).

Autor: Dinicola S; The Experts Group on Inositol in Basic and Clinical Research (EGOI), Rome, Italy.; Systems Biology Group Lab, Rome, Italy., Unfer V; The Experts Group on Inositol in Basic and Clinical Research (EGOI), Rome, Italy.; UniCamillus - Saint Camillus International University of Health Sciences, Rome, Italy., Soulage CO; The Experts Group on Inositol in Basic and Clinical Research (EGOI), Rome, Italy.; INSERM U1060, INSA de Lyon, University of Lyon, Université Claude Bernard Lyon 1, Villeurbanne, France., Yap-Garcia MIM; The Experts Group on Inositol in Basic and Clinical Research (EGOI), Rome, Italy.; St. Luke's Medical Center College of Medicine, William H. Quasha Memorial, Quezon, Philippines., Bevilacqua A; The Experts Group on Inositol in Basic and Clinical Research (EGOI), Rome, Italy.; Department of Dynamic, Clinical Psychology and Health, Sapienza University of Rome, Rome, Italy., Benvenga S; The Experts Group on Inositol in Basic and Clinical Research (EGOI), Rome, Italy.; Department of Clinical and Experimental Medicine, University of Messina, Messina, Italy., Barbaro D; The Experts Group on Inositol in Basic and Clinical Research (EGOI), Rome, Italy.; Director of U.O. Endocrinology in Livorno Hospital, Livorno, Italy., Wdowiak A; The Experts Group on Inositol in Basic and Clinical Research (EGOI), Rome, Italy.; Faculty of Medicine and Dentistry, Medical University of Lublin, Lublin, Poland., Nordio M; The Experts Group on Inositol in Basic and Clinical Research (EGOI), Rome, Italy.; A.S.L. RMF, Civitavecchia, Italy., Dewailly D; The Experts Group on Inositol in Basic and Clinical Research (EGOI), Rome, Italy.; Faculty of Medicine Henri Warembourg, University of Lille, Lille Cedex, France., Appetecchia M; The Experts Group on Inositol in Basic and Clinical Research (EGOI), Rome, Italy.; Oncological Endocrinology Unit, Regina Elena National Cancer Institute, IRCCS, Rome, Italy., Aragona C; The Experts Group on Inositol in Basic and Clinical Research (EGOI), Rome, Italy.; Systems Biology Group Lab, Rome, Italy., Espinola MSB; The Experts Group on Inositol in Basic and Clinical Research (EGOI), Rome, Italy.; Systems Biology Group Lab, Rome, Italy., Bizzarri M; The Experts Group on Inositol in Basic and Clinical Research (EGOI), Rome, Italy.; Systems Biology Group Lab, Rome, Italy.; Department of Experimental Medicine, Sapienza University of Rome, Rome, Italy., Cavalli P; The Experts Group on Inositol in Basic and Clinical Research (EGOI), Rome, Italy.; Humanitas Research Hospital, Rozzano, Milan, Italy., Colao A; The Experts Group on Inositol in Basic and Clinical Research (EGOI), Rome, Italy.; Department of Clinical Medicine and Surgery, Endocrinology, Diabetology and Andrology Unit, Italian Society of Endocrinology, Federico II University of Naples, Naples, Italy., D'Anna R; The Experts Group on Inositol in Basic and Clinical Research (EGOI), Rome, Italy.; Department of Human Pathology, University of Messina, Messina, Italy., Vazquez-Levin MH; The Experts Group on Inositol in Basic and Clinical Research (EGOI), Rome, Italy.; National Council of Scientific and Technical Research, Instituto de Biología y Medicina Experimental (IBYME), Buenos Aires, Argentina., Hernàndez Marin I; The Experts Group on Inositol in Basic and Clinical Research (EGOI), Rome, Italy.; Human Reproduction Department, Hospital Juárez de México, and Universidad Nacional Autónoma de México (UNAM), México, Mexico., Kamenov Z; The Experts Group on Inositol in Basic and Clinical Research (EGOI), Rome, Italy.; Department of Internal Medicine, University Hospital 'Alexandrovska', Clinic of Endocrinology and Metabolism, Medical University, Sofia, Bulgaria., Laganà AS; The Experts Group on Inositol in Basic and Clinical Research (EGOI), Rome, Italy.; Unit of Obstetrics and Gynecology, 'Paolo Giaccone' Hospital, Department of Health Promotion, Mother and Child Care, Internal Medicine and Medical Specialties (PROMISE), University of Palermo, Palermo, Italy., Monastra G; The Experts Group on Inositol in Basic and Clinical Research (EGOI), Rome, Italy., Montanino Oliva M; The Experts Group on Inositol in Basic and Clinical Research (EGOI), Rome, Italy.; Department of Obstetrics and Gynecology, Santo Spirito Hospital, Rome, Italy., Cenk Özay A; The Experts Group on Inositol in Basic and Clinical Research (EGOI), Rome, Italy.; Department of Obstetrics and Gynecology, Faculty of Medicine, Cyprus International University, Nicosia, Cyprus., Pintaudi B; The Experts Group on Inositol in Basic and Clinical Research (EGOI), Rome, Italy.; ASST Grande Ospedale Metropolitano Niguarda, Milan, Italy., Porcaro G; The Experts Group on Inositol in Basic and Clinical Research (EGOI), Rome, Italy.; Women's Health Centre, USL UMBRIA 2, Terni, Italy., Pustotina O; The Experts Group on Inositol in Basic and Clinical Research (EGOI), Rome, Italy.; Department of Obstetrics and Gynecology with Reproductive Medicine, F.I. Inozemtsev Academy of Medical Education, Saint Petersburg, Russian Federation., Pkhaladze L; The Experts Group on Inositol in Basic and Clinical Research (EGOI), Rome, Italy.; Zhordania and Khomasuridze Institute of Reproductology, Tbilisi, Georgia., Prapas N; The Experts Group on Inositol in Basic and Clinical Research (EGOI), Rome, Italy.; Third Department of OB-GYNAE, Aristotle University of Thessaloniki, and IVF Laboratory, IAKENTRO Fertility Centre, Thessaloniki, Greece., Roseff S; The Experts Group on Inositol in Basic and Clinical Research (EGOI), Rome, Italy.; Reproductive Endocrinology and Infertility, South Florida Institute for Reproductive Medicine (IVFMD), Jupiter, Florida, USA., Salehpour S; The Experts Group on Inositol in Basic and Clinical Research (EGOI), Rome, Italy.; Preventative Gynecology Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran., Stringaro A; The Experts Group on Inositol in Basic and Clinical Research (EGOI), Rome, Italy.; National Center for Drug Research and Evaluation, Italian National Institute of Health, Rome, Italy., Tugushev M; The Experts Group on Inositol in Basic and Clinical Research (EGOI), Rome, Italy.; Department of Reproductive Medicine, Clinical Embryology and Genetics of Samara State Medical University, Samara, Russian Federation., Unfer V; The Experts Group on Inositol in Basic and Clinical Research (EGOI), Rome, Italy.; A.G.Un.Co. Obstetrics and Gynecology Center, Rome, Italy., Vucenik I; The Experts Group on Inositol in Basic and Clinical Research (EGOI), Rome, Italy.; Department of Medical and Research Technology and Pathology, University of Maryland School of Medicine in Baltimore, Baltimore, Maryland, USA., Facchinetti F; The Experts Group on Inositol in Basic and Clinical Research (EGOI), Rome, Italy.; University of Modena and Reggio Emilia, Modena, Italy.; President Italian Society of Perinatal Medicine (SIMP), Modena, Italy.

Publikováno v: Gynecologic and obstetric investigation [Gynecol Obstet Invest] 2024; Vol. 89 (4), pp. 284-294. Date of Electronic Publication: 2024 Feb 19.