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pro vyhledávání: '"M. Tolson"'
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Autor:
Hendrik-Tobias Arkenau, Johann S. de Bono, Li Yan, Jeffrey R. Infante, Yung-Jue Bang, Sunil Sharma, Joseph P. Eder, Hyun Cheol Chung, Sun Young Rha, Jerry M. Tolson, Rakesh Kumar, Monica Motwani, Jiuhua Wu, Shanker Kalyana-Sundaram, Deborah A. Smith, M. Phillip DeYoung, Shaun Decordova, Karen Swales, Sae-Won Han, Howard A. Burris, Charlotte Lemech, Gopinath Ganji, Joaquin Mateo
Supplementary Table 7: Next-generation sequencing of tumor biopsy samples (see separate Excel file) Supplementary Table 8: Copy number variations for patients with tumor biopsy samples available (see separate Excel file) Supplementary Table 9: Summar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1dfa50e068207514fe340c2597b87452
https://doi.org/10.1158/1078-0432.22468446
https://doi.org/10.1158/1078-0432.22468446
Autor:
Hendrik-Tobias Arkenau, Johann S. de Bono, Li Yan, Jeffrey R. Infante, Yung-Jue Bang, Sunil Sharma, Joseph P. Eder, Hyun Cheol Chung, Sun Young Rha, Jerry M. Tolson, Rakesh Kumar, Monica Motwani, Jiuhua Wu, Shanker Kalyana-Sundaram, Deborah A. Smith, M. Phillip DeYoung, Shaun Decordova, Karen Swales, Sae-Won Han, Howard A. Burris, Charlotte Lemech, Gopinath Ganji, Joaquin Mateo
Supplementary Figure 1: Study design
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a39f1e4acd2ba5c60c4b80f85a5a4dc7
https://doi.org/10.1158/1078-0432.22468458.v1
https://doi.org/10.1158/1078-0432.22468458.v1
Autor:
Hendrik-Tobias Arkenau, Johann S. de Bono, Li Yan, Jeffrey R. Infante, Yung-Jue Bang, Sunil Sharma, Joseph P. Eder, Hyun Cheol Chung, Sun Young Rha, Jerry M. Tolson, Rakesh Kumar, Monica Motwani, Jiuhua Wu, Shanker Kalyana-Sundaram, Deborah A. Smith, M. Phillip DeYoung, Shaun Decordova, Karen Swales, Sae-Won Han, Howard A. Burris, Charlotte Lemech, Gopinath Ganji, Joaquin Mateo
Supplementary Figure 3: Glucose and insulin levels after treatment with GSK2636771 in fasted mice.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::369716f0008acebd72ad590670fe3760
https://doi.org/10.1158/1078-0432.22468452.v1
https://doi.org/10.1158/1078-0432.22468452.v1
Autor:
Hendrik-Tobias Arkenau, Johann S. de Bono, Li Yan, Jeffrey R. Infante, Yung-Jue Bang, Sunil Sharma, Joseph P. Eder, Hyun Cheol Chung, Sun Young Rha, Jerry M. Tolson, Rakesh Kumar, Monica Motwani, Jiuhua Wu, Shanker Kalyana-Sundaram, Deborah A. Smith, M. Phillip DeYoung, Shaun Decordova, Karen Swales, Sae-Won Han, Howard A. Burris, Charlotte Lemech, Gopinath Ganji, Joaquin Mateo
Background: The PI3K/protein kinase B (AKT) pathway is commonly activated in several tumor types. Selective targeting of p110β could result in successful pathway inhibition while avoiding the on- and off-target effects of pan-PI3K inhibitors. GSK263
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e88911e3f343071194a98323816102ae
https://doi.org/10.1158/1078-0432.c.6526947.v1
https://doi.org/10.1158/1078-0432.c.6526947.v1
Autor:
Hendrik-Tobias Arkenau, Johann S. de Bono, Li Yan, Jeffrey R. Infante, Yung-Jue Bang, Sunil Sharma, Joseph P. Eder, Hyun Cheol Chung, Sun Young Rha, Jerry M. Tolson, Rakesh Kumar, Monica Motwani, Jiuhua Wu, Shanker Kalyana-Sundaram, Deborah A. Smith, M. Phillip DeYoung, Shaun Decordova, Karen Swales, Sae-Won Han, Howard A. Burris, Charlotte Lemech, Gopinath Ganji, Joaquin Mateo
Supplementary Table 1: 3 + 3 dose escalation guidelines Supplementary Table 2: Customized sequencing panel Supplementary Table 3: Summary of AEs occurring in >20% of all patients, treatment-related AEs and SAEs Supplementary Table 4: PK parameters fo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b2914c781168e583ece8cd2996b4a24
https://doi.org/10.1158/1078-0432.22468461
https://doi.org/10.1158/1078-0432.22468461
Autor:
Hendrik-Tobias Arkenau, Johann S. de Bono, Li Yan, Jeffrey R. Infante, Yung-Jue Bang, Sunil Sharma, Joseph P. Eder, Hyun Cheol Chung, Sun Young Rha, Jerry M. Tolson, Rakesh Kumar, Monica Motwani, Jiuhua Wu, Shanker Kalyana-Sundaram, Deborah A. Smith, M. Phillip DeYoung, Shaun Decordova, Karen Swales, Sae-Won Han, Howard A. Burris, Charlotte Lemech, Gopinath Ganji, Joaquin Mateo
Supplementary Figure 2: LNCAP and DU-145 prostate cancer cells were treated with 1 or 10 μM GSK2636771 for up to 48 hours and probed with the indicated antibodies
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a3127a7afbf6dc0a774636c87ed83be
https://doi.org/10.1158/1078-0432.22468455
https://doi.org/10.1158/1078-0432.22468455
Autor:
Hendrik-Tobias Arkenau, Johann S. de Bono, Li Yan, Jeffrey R. Infante, Yung-Jue Bang, Sunil Sharma, Joseph P. Eder, Hyun Cheol Chung, Sun Young Rha, Jerry M. Tolson, Rakesh Kumar, Monica Motwani, Jiuhua Wu, Shanker Kalyana-Sundaram, Deborah A. Smith, M. Phillip DeYoung, Shaun Decordova, Karen Swales, Sae-Won Han, Howard A. Burris, Charlotte Lemech, Gopinath Ganji, Joaquin Mateo
Supplementary Figure 4: Investigation of the p.L1049R mutation identified in a patient with castration-resistant prostate cancer.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::392ff8d29623d05c386df7a5131a0b6e
https://doi.org/10.1158/1078-0432.22468449
https://doi.org/10.1158/1078-0432.22468449
Autor:
Cris Martin P. Jacoba, Mohamed Ashraf, Jerry D. Cavallerano, Ann M. Tolson, Dorothy Tolls, Enrico Pellegrini, Alan Fleming, Jennifer K. Sun, Lloyd Paul Aiello, Paolo S. Silva
Publikováno v:
JAMA Ophthalmol
IMPORTANCE: Methods that increase visible retinal area (VRA; measured in millimeters squared) may improve identification of diabetic retinopathy (DR) lesions. OBJECTIVE: To evaluate the association of dilation and manual eyelid lifting (MLL) with VRA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91463e3d22302724af574b0042c0c57c
https://pubmed.ncbi.nlm.nih.gov/35201258
https://pubmed.ncbi.nlm.nih.gov/35201258
Autor:
K. Harbour, Laura Wiffen, B. Reeve, C. Mason, Anoop Chauhan, Lauren Fox, Rachel Harvey, M. Tolson, Tom C. Brown, R. De Vos, S. Folini
Publikováno v:
Virtually perfect: remote medicine and digital health.
P78 Figure 1ConclusionThis electronic system re-vitalised the use of PEF in our asthma clinic;it is paper-light, patient-friendly and has increased our PEF diary responses, without additional cost or the requirement of a smart-phone. An average daily
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::14884e9211cbf0899b88703351d191ba
https://doi.org/10.1136/thorax-2021-btsabstracts.188
https://doi.org/10.1136/thorax-2021-btsabstracts.188