Zobrazeno 1 - 10
of 48
pro vyhledávání: '"M. Todd King"'
Autor:
M. Todd King
Publikováno v:
Frontiers in Physiology, Vol 14 (2023)
Externí odkaz:
https://doaj.org/article/1099e807b9534713935b2cdf5914f7f6
Autor:
Vikrant R. Mahajan, Sophie K. Elvig, Leandro F. Vendruscolo, George F. Koob, Valerie L. Darcey, M. Todd King, Henry R. Kranzler, Nora D. Volkow, Corinde E. Wiers
Publikováno v:
Frontiers in Psychiatry, Vol 12 (2021)
Alcohol use disorder (AUD) is a chronic, relapsing brain disorder, characterized by compulsive alcohol seeking and disrupted brain function. In individuals with AUD, abstinence from alcohol often precipitates withdrawal symptoms than can be life thre
Externí odkaz:
https://doaj.org/article/6ccbabd437f746bd9c676280ae042a7e
Autor:
Phung N. Thai, Charles V. Miller, M. Todd King, Saul Schaefer, Richard L. Veech, Nipavan Chiamvimonvat, Donald M. Bers, Elena N. Dedkova
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 10, Iss 19 (2021)
Background Heart failure is responsible for approximately 65% of deaths in patients with type 2 diabetes mellitus. However, existing therapeutics for type 2 diabetes mellitus have limited success on the prevention of diabetic cardiomyopathy. The aim
Externí odkaz:
https://doaj.org/article/14efa7dcf45f45d09137d5ef645178a1
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 3, p 1044 (2020)
Because of a decreased sensitivity toward insulin, a key regulator of pyruvate dehydrogenase (PDH), Alzheimer’s patients have lower brain glucose utilization with reductions in Tricarboxylic Acid (TCA) cycle metabolites such as citrate, a precursor
Externí odkaz:
https://doaj.org/article/89f904fb40e6466b8b50d9d72ecddf09
Autor:
Vikrant R. Mahajan, Jacob A. Nadel, M. Todd King, Robert J. Pawlosky, Margaret I. Davis, Richard L. Veech, David M. Lovinger, Armando G. Salinas
BackgroundParkinson’s disease is a progressive, neurodegenerative disease characterized by motor dysfunction and dopamine deficits. The MitoPark mouse recapitulates several facets of Parkinson’s disease, including gradual development of motor def
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dd7853a2583008db616bd37735cac652
https://doi.org/10.1101/2022.11.14.516368
https://doi.org/10.1101/2022.11.14.516368
Publikováno v:
The FASEB Journal. 33:13126-13130
Cell membrane potential and inorganic ion distributions are currently viewed from a kinetic electric paradigm, which ignores thermodynamics. The resting membrane potential is viewed as a diffusion ...
Autor:
Leandro F. Vendruscolo, Nora D. Volkow, Corinde E. Wiers, Sophie K. Elvig, Vikrant R. Mahajan, George F. Koob, Valerie L. Darcey, M. Todd King, Henry R. Kranzler
Publikováno v:
Frontiers in Psychiatry
Frontiers in Psychiatry, Vol 12 (2021)
Frontiers in Psychiatry, Vol 12 (2021)
Alcohol use disorder (AUD) is a chronic, relapsing brain disorder, characterized by compulsive alcohol seeking and disrupted brain function. In individuals with AUD, abstinence from alcohol often precipitates withdrawal symptoms than can be life thre
Autor:
Richard L. Veech, Elena N. Dedkova, Nipavan Chiamvimonvat, Charles Miller, M. Todd King, Phung N. Thai, Saul Schaefer, Donald M. Bers
Publikováno v:
Journal of the American Heart Association. 10(19)
Background Heart failure is responsible for approximately 65% of deaths in patients with type 2 diabetes mellitus. However, existing therapeutics for type 2 diabetes mellitus have limited success on the prevention of diabetic cardiomyopathy. The aim
Autor:
Deborah M. Muoio, Timothy R. Koves, Carla J. Weinheimer, Richard L. Veech, Richard W. Gross, Attila Kovacs, Kelly D. Pyles, Trevor M. Shew, Kyle S. McCommis, M. Todd King, Olga Ilkayeva, Dakota R. Kamm, Brian N. Finck, Brian J. DeBosch
Publikováno v:
Nat Metab
The myocardium is metabolically flexible; however, impaired flexibility is associated with cardiac dysfunction in conditions including diabetes and heart failure. The mitochondrial pyruvate carrier (MPC) complex, composed of MPC1 and MPC2, is require
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7af51cfcfd656fcb0072d8d617a575b2
https://europepmc.org/articles/PMC7957960/
https://europepmc.org/articles/PMC7957960/
Autor:
Attila Kovacs, Kelly D. Pyles, Olga Ilkayeva, Trevor M. Shew, M. Todd King, Carla J. Weinheimer, Richard L. Veech, Timothy R. Koves, Brian J. DeBosch, Dakota R. Kamm, Brian N. Finck, Richard W. Gross, Kyle S. McCommis, Deborah M. Muoio
The myocardium is metabolically flexible and can use fatty acids, glucose, lactate/pyruvate, ketones, or amino acids to fuel mechanical work. However, impaired metabolic flexibility is associated with cardiac dysfunction in conditions including diabe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9cc65355ed0061e463575dc8d97d70e2