Zobrazeno 1 - 10
of 18
pro vyhledávání: '"M. Tino Unlap"'
Autor:
Kathy Nugent, M. Tino Unlap, Joseph Garner, Jonathan B. Waugh, Norman E. Bolus, Emma Heard, Remo George, Ashley Glaze, Jenna Pickering
Publikováno v:
American Journal of Biochemistry and Biotechnology. 10:40-49
The ability of the pathogen Mycobacterium Tuberculosis (MTB) to invade and survive within macrophages of granulomas is attributed to the product of the Mammalian Cell Entry (MCE) operon whose gene, mce4A , encodes a cholesterol transporter that trans
Publikováno v:
Current Hypertension Reviews. 6:260-265
Oxidative stress is characterized by the elevation of reactive oxygen species (ROS) including the superoxide anion, hydrogen peroxide and the hydroxyl radical. In almost all animal models of hypertension and humans, reducing oxidative stress with ant
Autor:
Elyana Marques, Celso Carvalho, M. Tino Unlap, Jonathan B. Waugh, Remo George, Renata Cavalcante
Tuberculosis is one of the leading infectious diseases plaguing mankind and is mediated by the facultative pathogen, Mycobacterium tuberculosis (MTB). Once the pathogen enters the body, it subverts the host immune defenses and thrives for extended pe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23f92addf6e0267021a9cc2adbf49462
https://europepmc.org/articles/PMC4543811/
https://europepmc.org/articles/PMC4543811/
Publikováno v:
American Journal of Physiology-Renal Physiology. 279:F177-F184
The Dahl/Rapp rat model of hypertension is characterized by a marked increase in blood pressure and a progressive fall in glomerular filtration rate when salt-sensitive (S) rats are placed on an 8% NaCl diet. On the same diet, the salt-resistant (R)
Publikováno v:
American Journal of Physiology-Renal Physiology. 276:F567-F573
The present studies were performed to assess Na+/Ca2+exchange activity in afferent and efferent arterioles from Dahl/Rapp salt-resistant (R) and salt-sensitive (S) rats. Renal arterioles were obtained by microdissection from S and R rats on either a
Lithium Attenuates Nerve Growth Factor–Induced Activation of AP-1 DNA Binding Activity in PC12 Cells
Autor:
Richard S. Jope, M. Tino Unlap
Publikováno v:
Neuropsychopharmacology. 17:12-17
This investigation tested if lithium, the primary therapeutic agent for bipolar mood disorder, modulated activation of the AP-1 transcription factor in PC12 cells treated with nerve growth factor (NGF), which induces robust responses in these cells.
Publikováno v:
Journal of Biotechnology & Biomaterials.
In latent TB, the ability of Mycobacterium tuberculosis to invade and survive within macrophages of the pulmonary granuloma is attributed to protein products of mammalian cell entry (mce4) operon genes (A-F). These are cholesterol transporters which
Publikováno v:
Journal of Biotechnology & Biomaterials.
GHK-Cu is a tripeptide that is found in plasma and increases fibroblast proliferation and is widely used in wound healing creams. Studies show that GHK-Cu stimulates the level of p63, a member of the antitumor suppressor family which includes p53 and
Autor:
Roger A. Laine, M. Tino Unlap
Publikováno v:
Journal of Biotechnology & Biomaterials.
Dopamine does not penetrate the blood-brain barrier and IPX 750, a dopamine glycoconjugate, is designed to improve dopamine transport across the blood brain barrier. IPX-750 binds to D1/D5 receptors in vitro and eliminates Parkinson’s disease sympt
Autor:
Elizabeth Bates, P. Darwin Bell, Peter Komlosi, M. Tino Unlap, Gergely Gy Kovacs, Brian J. Siroky, Corey L. Williams, Iantha Williams
Publikováno v:
Hypertension (Dallas, Tex. : 1979). 42(3)
The Na + /Ca 2+ exchanger regulates intracellular calcium ([Ca 2+ ] i ), and attenuation of Na + /Ca 2+ exchange by oxidative stress might lead to dysregulation of [Ca 2+ ] i . We have shown that the Na + /Ca 2+ exchanger differs functionally and at