Zobrazeno 1 - 10
of 84
pro vyhledávání: '"M. Teresa Miras-Portugal"'
Autor:
Edward H. Beamer, Jeronimo Jurado-Arjona, Eva M. Jimenez-Mateos, James Morgan, Cristina R. Reschke, Aidan Kenny, Gioacchino de Leo, Luis A. Olivos-Oré, Marina Arribas-Blázquez, Stephen F. Madden, Jesús Merchán-Rubira, Norman Delanty, Michael A. Farrell, Donncha F. O’Brien, Jesus Avila, Miguel Diaz-Hernandez, M. Teresa Miras-Portugal, Antonio R. Artalejo, Felix Hernandez, David C. Henshall, Tobias Engel
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 11 (2018)
Prolonged seizures (status epilepticus, SE) may drive hippocampal dysfunction and epileptogenesis, at least partly, through an elevation in neurogenesis, dysregulation of migration and aberrant dendritic arborization of newly-formed neurons. MicroRNA
Externí odkaz:
https://doaj.org/article/19234c54086942beaaaf52c8affce5f5
Autor:
M. Teresa Miras-Portugal, Juan I. Diaz-Hernandez, Rosa Gomez-Villafuertes, Miguel Diaz-Hernandez, Antonio R. Artalejo, Javier Gualix
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 13, Iss C, Pp 176-181 (2015)
Amyloid precursor protein (APP) is expressed in a large variety of neural and non-neural cells. The balance between non-pathogenic and pathologic forms of APP processing, mediated by α-secretase and β-secretase respectively, remains a crucial step
Externí odkaz:
https://doaj.org/article/30d6092cc8e444649b235bdcdcfcd5f5
Autor:
Christa E. Müller, Esmerilda G. Delicado, Doreen Thor, Beibei Li, M. Teresa Miras-Portugal, Kenneth A. Jacobson, Raquel Pérez-Sen, Ivana Novak, Ivar von Kügelgen, Christian Gachet, Charles Kennedy, Beili Wu, Zhenlin Yang, Torsten Schöneberg
Publikováno v:
Br J Pharmacol
Eight G protein‐coupled P2Y receptor subtypes respond to extracellular adenine and uracil mononucleotides and dinucleotides. P2Y receptors belong to the δ group of rhodopsin‐like GPCRs and contain two structurally distinct subfamilies: P2Y(1), P
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23c63dfc833f2c5b5752e6ea938ced01
https://strathprints.strath.ac.uk/72461/1/Jacobson_etal_2020_Update_of_P2Y_Receptor_pharmacology_IUPHAR.pdf
https://strathprints.strath.ac.uk/72461/1/Jacobson_etal_2020_Update_of_P2Y_Receptor_pharmacology_IUPHAR.pdf
Autor:
Alejandro, Martínez-Águila, Begoña, Fonseca, María J, Pérez de Lara, M Teresa, Miras-Portugal, Rosa, Gómez-Villafuertes, Gonzalo, Carracedo, Jesús, Pintor
Publikováno v:
Molecular Vision
Purpose The objective of this study was to evaluate the changes in the melatoninergic receptors of DBA/2J and C57BL/6J mice with the development of glaucoma. DBA/2J mice are widely used to study the physiopathology of glaucoma due to the similarities
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::3b3dd1c0776779acd751c771123d7317
https://pubmed.ncbi.nlm.nih.gov/32818016
https://pubmed.ncbi.nlm.nih.gov/32818016
Autor:
Felipe Ortega, Javier Gualix, Rosa Gómez-Villafuertes, Juan Ignacio Díaz-Hernández, Raquel Pérez-Sen, Esmerilda G. Delicado, M. Teresa Miras-Portugal, Antonio R. Artalejo
Publikováno v:
Neuropharmacology. 104:243-254
Brain injury generates the release of a multitude of factors including extracellular nucleotides, which exhibit bi-functional properties and contribute to both detrimental actions in the acute phase and also protective and reparative actions in the l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::abb260d0e13611e4d65a8b2a841a6144
https://doi.org/10.1016/j.neuropharm.2015.09.002
https://doi.org/10.1016/j.neuropharm.2015.09.002
Publikováno v:
Purinergic Signalling
Before being released, nucleotides are stored in secretory vesicles through the vesicular nucleotide transporter (VNUT). Once released, extracellular ATP participates in neuronal differentiation processes. Thus, the expression of a functional VNUT co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69b38e6c45fbcfe1f35c22bde90a3111
http://europepmc.org/articles/PMC4425722
http://europepmc.org/articles/PMC4425722
Autor:
Juan Ignacio Díaz-Hernández, Rosa Gómez-Villafuertes, Miguel Díaz-Hernández, Antonio R. Artalejo, Javier Gualix, M. Teresa Miras-Portugal
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 13, Iss C, Pp 176-181 (2015)
Computational and Structural Biotechnology Journal
Computational and Structural Biotechnology Journal
Amyloid precursor protein (APP) is expressed in a large variety of neural and non-neural cells. The balance between non-pathogenic and pathologic forms of APP processing, mediated by α-secretase and β-secretase respectively, remains a crucial step
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f465b44c7b01ad3821b1f1ec050e0b98
https://doi.org/10.1016/j.csbj.2015.02.005
https://doi.org/10.1016/j.csbj.2015.02.005
Publikováno v:
The Journal of neuroscience : the official journal of the Society for Neuroscience. 37(30)
The proposed presence of P2X7 receptor (P2X7R) in neurons has been the source of some contention. Initial studies suggested an absence of P2X7R mRNA in neurons, and the apparent nonspecificity of the antibodies used to identify P2X7R raised further d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26ea865eccb6b7f4a4fd0a3cf0338e45
https://pubmed.ncbi.nlm.nih.gov/28747389
https://pubmed.ncbi.nlm.nih.gov/28747389
Autor:
Miguel Díaz-Hernández, Catherine Mooney, James Morgan, Alba Jimenez-Pacheco, Claire M. Mooney, Cristina R. Reschke, Caoimhín G. Concannon, Amaya Sanz-Rodriguez, Elena Langa, Eleonora Lugarà, Guillaume Mesuret, Antonio R. Artalejo, Luiz Fernando Almeida Silva, Tobias Engel, Michael A. Letavic, Luis Alcides Olivos-Oré, Eva M. Jimenez-Mateos, Detlev Boison, Marina Arribas-Blázquez, David C. Henshall, Anindya Bhattacharya, M. Teresa Miras-Portugal
Publikováno v:
Scientific Reports
The ATP-gated ionotropic P2X7 receptor (P2X7R) modulates glial activation, cytokine production and neurotransmitter release following brain injury. Levels of the P2X7R are increased in experimental and human epilepsy but the mechanisms controlling P2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f02dee95afef6ac9305e91f167c4309d
http://europepmc.org/articles/PMC4668358
http://europepmc.org/articles/PMC4668358
Autor:
Michael A. Farrell, Donncha F. O’Brien, Luis Alcides Olivos-Oré, Tobias Engel, Ronan M. Conroy, Norman Delanty, Antonio R. Artalejo, Miguel Díaz-Hernández, Alba Jimenez-Pacheco, Amaya Sanz-Rodriguez, Marina Arribas-Blázquez, Anindya Bhattacharya, Michael A. Letavic, David C. Henshall, Mariana Alves, M. Teresa Miras-Portugal
Publikováno v:
The Journal of neuroscience : the official journal of the Society for Neuroscience. 36(22)
Neuroinflammation is thought to contribute to the pathogenesis and maintenance of temporal lobe epilepsy, but the underlying cell and molecular mechanisms are not fully understood. The P2X7 receptor is an ionotropic receptor predominantly expressed o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5fd7a00d70a74748b1d09ff8fa49806b
https://pubmed.ncbi.nlm.nih.gov/29844763
https://pubmed.ncbi.nlm.nih.gov/29844763