RIPK3-deficient mice were not protected from nephrotoxic nephritis

Autor: N. R. Hill, H. T. Cook, C. D. Pusey, R. M. Tarzi

Publikováno v: BMC Nephrology, Vol 19, Iss 1, Pp 1-8 (2018)

Abstract Background Necrotizing glomerular lesions are a feature of severe glomerulonephritis. Unlike apoptosis, cellular necrosis has the potential to release damage-associated proteins into the microenvironment, thereby potentiating inflammation. U

Externí odkaz: https://doaj.org/article/e83b3abd8b32493f8e6813f614c818a1

Advanced imaging for quantification of abnormalities in the salivary glands of patients with primary Sjögren’s syndrome

Autor: Nicolas Wisniacki, Azeem Saleem, Paul Galette, Coziana Ciurtin, Ruth M. Tarzi, Teresa Fuller, Kathleen Port, Robert L. Janiczek, Davide Lucchesi, Calum Gray, Marius de Groot, Pilar Jimenez-Royo, Anwar R. Tappuni, Michele Bombardieri, Michalis Kostapanos, Mats Bergström, Elena Pontarini, Natasha Jordan, Nirav Ratia, André van Maurik, Neel Patel, Lucy E Kershaw, Graham E. Searle

Publikováno v: Jimenez-royo, P, Bombardieri, M, Ciurtin, C, Kostapanos, M, Tappuni, A R, Jordan, N, Saleem, A, Fuller, T, Port, K, Pontarini, E, Lucchesi, D, Janiczek, R L, Galette, P, Searle, G E, Patel, N, Kershaw, L, Gray, C, Ratia, N, van Maurik, A, de Groot, M, Wisniacki, N, Bergstrom, M & Tarzi, R 2021, ' Advanced imaging for quantification of abnormalities in the salivary glands of patients with primary Sjögren's Syndrome ', Rheumatology, vol. 60, no. 5, pp. 2396–2408 . https://doi.org/10.1093/rheumatology/keaa624
Rheumatology (Oxford, England)

Objectives To assess non-invasive imaging for detection and quantification of gland structure, inflammation and function in patients with primary Sjogren's syndrome (pSS) using PET-CT with 11C-Methionine (11C-MET; radiolabelled amino acid), and 18F-f

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb3aca584b8b2814615a95056b6a1eea
https://doi.org/10.1093/rheumatology/keaa624

The Trump Divide and Partisan Attitudes Regarding US Foreign Policy: Select Theoretical and Empirical Observations

Autor: Shah M. Tarzi

Publikováno v: International Studies. 56:46-57

This article presents select data, recent trends and empirical analysis concerning American voters’ attitudes on American foreign policy in the Trump era. Accordingly, it addresses several vital questions: (a) whether and to what extent Trump Repub

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::75e32faa928bee58d4b15f716ef8015e
https://doi.org/10.1177/0020881718824488

Endovascular repair of traumatic aortic isthmic rupture: Early and mid-term results

Autor: R. Miri, M. Ben Mrad, Y. Khadhar, J. Ziadi, Z. Daoud, M. Tarzi, I. Bounawes, S. Ben Omrane, F. Ghedira, B. Derbel, M. Ben Hammamia, T. Kalfat, Raouf Denguir, N. Krarti, Mohamed Koubaa, A. Lagha, E. Ben Abdelaziz

Publikováno v: Journal de medecine vasculaire. 45(5)

Summary Introduction Conventional open repair of a traumatic aortic isthmic rupture is associated with a significantly high mortality and morbidity rates. Thoracic endovascular aortic repair (TEVAR) is currently often performed because it is a less i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89a18c6b14d276647880378e245107dd
https://pubmed.ncbi.nlm.nih.gov/32862982

Depletion of LAG-3

Autor: Joanne, Ellis, Daniel, J B Marks, Naren, Srinivasan, Christine, Barrett, Thomas G, Hopkins, Anna, Richards, Rainard, Fuhr, Muna, Albayaty, Martin, Coenen, Lia, Liefaard, Karen, Leavens, Katherine L, Nevin, Shuo, Tang, Stephen A, Hughes, Léa, Fortunato, Ken, Edwards, Yi, Cui, Rabia, Anselm, Christopher J, Delves, Emilie, Charles, Maria, Feeney, Thomas M, Webb, Sara J, Brett, Tim S, Schmidt, John, Stone, Caroline O S, Savage, Nicolas, Wisniacki, Ruth M, Tarzi

Publikováno v: Clinical Pharmacology and Therapeutics

Activated T cells drive a range of immune‐mediated inflammatory diseases. LAG‐3 is transiently expressed on recently activated CD4+ and CD8+ T cells. We describe the engineering and first‐in‐human clinical study (NCT02195349) of GSK2831781 (a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::f23427490f0b1e1cb4970397cb5df0a0
https://pubmed.ncbi.nlm.nih.gov/33113155