Zobrazeno 1 - 10
of 38
pro vyhledávání: '"M. T. Valenzuela"'
Autor:
M T Valenzuela, C Urquidi
Publikováno v:
European Journal of Public Health. 30
Background EPI is one of the successful public health programs for the control and prevention of infectious diseases worldwide. In Latin America and the Caribbean, EPI achieved high rates of vaccination and reached both the eradication of poliomyelit
Autor:
Francisco Javier Oliver, A Zuluaga, M. T. Valenzuela, M. Villalobos, J M Ruiz de Almodóvar, María Isabel Núñez, R Galisteo
Publikováno v:
European Urology. 42:622-630
Objective: This study was undertaken to investigate whether hypermethylation in p16 INK4a gene promoter could serve as plasma biomarker of bladder cancer. Methods and Patients: We examined the p16 INK4a status using methylation-specific PCR in 86 can
Autor:
María Isabel Núñez, M. Villalobos, Rosario Del Moral, R. Guerrero, Escarlata López, M. T. Valenzuela, José Mariano Ruiz de Almodóvar, Damián Guirado
Publikováno v:
Radiotherapy and Oncology. 62:327-333
Purpose : The purpose of this study was to determine whether the distribution of sensitivities in breast cancer patients, measured using a DNA damage assay on lymphocytes, is likely to provide sufficient discrimination to enable the reliable identifi
Publikováno v:
Radiotherapy and Oncology. 54:261-271
Background and purpose : We have investigated whether the protective role of the G2 checkpoint has increasing importance when the p53-dependent G1 checkpoint is inactivated. Materials and methods: We have studied the differential effect of caffeine b
Autor:
Marı́a Rosario Guerrero, María Isabel Núñez, José Mariano Ruiz de Almodóvar, M. Villalobos, M. T. Valenzuela
Publikováno v:
Journal of Chromatography A. 871:321-330
Apoptosis is a type of cellular death but also directly regulates tumorigenesis through different gene expression. This phenomenon is often used as end-point in studies of radio- and chemosensitivity of cancer cells. Restriction DNA fragments have be
Autor:
J. J. Eady, R. Guerrero, M. T. Valenzuela, J M Ruiz de Almodóvar, Lovell A Jones, M. Villalobos, Trevor J. McMillan, Eva Siles, María Isabel Núñez
Publikováno v:
British Journal of Cancer
Apoptosis and necrosis are two different forms of cell death that can be induced by cytotoxic stress, such as ionizing radiation. We have studied the importance of apoptotic death induced after treatment with 6 Gy of gamma-irradiation in a panel of e
Autor:
M. T. Valenzuela, J. Mariano Ruiz de Almodóvar, Trevor J. McMillan, M. Villalobos, V. Pedraza, María Isabel Núñez, Eva Siles
Publikováno v:
International Journal of Cancer. 72:307-312
To assess the potential relationship between p53 and p16 proteins in the cellular response to stress, we have examined the levels of these proteins in a series of human tumor cell lines after treatment with either ionizing radiation or hyperthermia.
Autor:
M. Villalobos, J M Ruiz de Almodóvar, M. T. Valenzuela, Eva Siles, María Isabel Núñez, Trevor J. McMillan, V. Pedraza, A. T. Gordon
Publikováno v:
British Journal of Cancer
We examined the relationship between p53 levels before and after irradiation, radiation-induced cell cycle delays, apoptotic cell death and radiosensitivity in a panel of eight human tumour cell lines. The cell lines differed widely in their clonogen
Autor:
J M Ruiz de Almodóvar, Eva Siles, D. Becerra, Nicolás Olea, M. T. Valenzuela, María Isabel Núñez, M. Villalobos, V. Pedraza
Publikováno v:
International Journal of Radiation Biology. 70:161-169
Treatments which inhibit or retard progression of the cell through the cell cycle have been reported to reduce the effectiveness of ionizing radiation by increasing cellular radioresistance. We studied cellular radiosensitivity and radiation-induced
Autor:
Nicolás Olea, M. T. Valenzuela, M. Villalobos, Trevor J. McMillan, V. Pedraza, María Isabel Núñez, J M Ruiz de Almodóvar
Publikováno v:
British Journal of Cancer
Five established human breast cancer cell lines and one established human bladder cancer cell line of varying radiosensitivity have been used to determine whether the rejoining of DNA double-strand breaks (dsbs) shows a correlation with radiosensitiv