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Non-cell autonomous induction of apoptosis and loss of posterior structures by activation domain-specific interactions of Oct-1 in the Xenopus embryo

Autor: van der Vliet Pc, Josi Peterson-Maduro, M. T. Mathu, Olivier Destrée, Gert Jan C. Veenstra

Publikováno v: Cell death and differentiation. 5(9)

Oct-1, a member of the POU family of transcription factors, is expressed at relatively high levels in ectodermal and mesodermal cell lineages during early Xenopus embryogenesis (Veenstra et al, 1995). Here we show that overexpression of Oct-1 induces

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c1821a1ffbe2d6ecbcd842811280640a
https://pubmed.ncbi.nlm.nih.gov/10200537

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The Oct-1 POU domain directs developmentally regulated nuclear translocation in Xenopus embryos

Autor: Gert Jan C. Veenstra, Olivier Destrée, M. T. Mathu

Publikováno v: Biological chemistry. 380(2)

Early embryonic development in Xenopus is characterized by transcriptional repression which is relieved at the mid-blastula stage. Here we show that most of the maternally inherited POU domain transcription factor Oct-1 is retained in the cytoplasm d

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7b5e59f49a686dd7cdd81ca92b31346
https://pubmed.ncbi.nlm.nih.gov/10195432

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