Zobrazeno 1 - 10
of 116
pro vyhledávání: '"M. T. El-Kolaly"'
Publikováno v:
BioNanoScience. 13:13-25
Autor:
M. T. El-Kolaly, Noha A. Bayoumi
Publikováno v:
Radiochimica Acta. 109:459-475
The rapid progress of nanomedicine field has a great influence on the different tumor therapeutic trends. It achieves a potential targeting of the therapeutic agent to the tumor site with neglectable exposure of the normal tissue. In nuclear medicine
Autor:
Tamer M. Sakr, Mohamed M. Swidan, M. T. El-Kolaly, M. A. Motaleb, Omneya Mohammed Khowessah, A. Abd El-Bary
Publikováno v:
European Journal of Pharmaceutical Sciences. 122:239-245
Nanotechnology may be applied in medicine where the utilization of nanoparticles (≤100 nm) for the delivery and targeting of theranostic agents is at the forefront of projects in cancer nano-science. This study points a novel one step synthesis app
Publikováno v:
Cancer Biotherapy and Radiopharmaceuticals. 33:221-232
Background: Recently, the direct intratumoral (i.t.) injection of anticancer agents has been investigated. A newly synthesized Antineoplaston A10 analog 3-(4-methoxybenzoylamino)-2,6-piperidinedione (MPD) showed an antitumor activity in human breast
Publikováno v:
International Journal of Pharmaceutics. 545:240-253
A10, (3-phenylacetylamino-2,6-piperidinedione), is a natural peptide with broad antineoplastic activity. Recently, in vitro antitumor effect of a new A10 analog [3-(4-methoxybenzoylamino)-2,6-piperidinedione] (MPD) has been verified. However, poor aq
Publikováno v:
European Journal of Pharmaceutical Sciences. 111:526-533
Nitazoxanide [2-(Acetyloxy)-N-(5-nitro-2-thiazolyl)benzamide], usually referred as NTZ, is an antiparasites drug with a potential anti-cancer reactivity. However, the bioavailability of nitazoxanide is limited due to its poor water solubility. In thi
Autor:
M. T. El-Kolaly, A. Abd El-Bary, Mohamed M. Swidan, Mohamed Abd El-Motaleb, Omnya M. Khowessah, Tamer M. Sakr
Publikováno v:
Daru : journal of Faculty of Pharmacy, Tehran University of Medical Sciences. 27(1)
BACKGROUND: The evolution of nanoparticles has gained prominence as platforms for developing diagnostic and/or therapeutic radiotracers. This study aims to develop a novel technique for fabricating a tumor diagnostic probe based on iron oxide nanopar
Publikováno v:
Radiochimica Acta. 103:777-787
Cladribine, a purine analogue antimetabolite, was radioiodinated with 125I via direct electrophilic substitution reaction. The maximum radiochemical yield (92.5 ± 0.8%) was obtained when the reaction was done at ambient temperature for 30 min using
Autor:
A. Abd El-Bary, M. T. El-Kolaly, Tamer M. Sakr, O. M. A. Khoweysa, Ahmed B. Ibrahim, M. A. Motaleb
Publikováno v:
Journal of Radioanalytical and Nuclear Chemistry. 303:967-975
This study describes the preparation of radioiodinated anastrozole and epirubicin and their biological evaluation as potential solid tumor imaging gents. Radioiodinated anastrozole and epirubicin were successfully prepared via direct electrophilic su
Publikováno v:
Journal of Labelled Compounds and Radiopharmaceuticals. 57:593-599
Acebutolol was successfully labeled with (125) I via direct electrophilic substitution reaction. Radioiodinated acebutolol was prepared with a maximum radiochemical yield of 96.5 ± 0.3% and in vitro stability up to 72 h. The in vivo biological distr