Výsledky vyhledávání - "M. T. BAYLISS"

TNF?-stimulated gene product (TSG-6) and its binding protein, I?I, in the human intervertebral disc: new molecules for the disc

Autor: Sally Roberts, S. Griffin, M. T. Bayliss, Helena Evans, Caroline M. Milner, Anthony J. Day, Stephen M. Eisenstein, Jill P. G. Urban, J. Menage, Marilyn S. Rugg

Publikováno v: European Spine Journal. 14:36-42

Inflammation and irritation of the nerve roots has been indicated as an important factor in the pain associated with symptomatic disc herniations. Tumour necrosis factor alpha (TNFalpha) is now believed to be involved in this pathway. TNFalpha causes

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::291bb39847af3a65428cb1fc6db9276b
https://doi.org/10.1007/s00586-004-0798-x

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Suppression of cartilage matrix gene expression in upper zone chondrocytes of osteoarthritic cartilage

Autor: J. Dudhia, S. I. Vornehm, G. Zeiler, M. T. Bayliss, K von der Mark, Thomas Aigner

Publikováno v: Arthritis & Rheumatism. 40:562-569

Objective. To evaluate the anabolic activity of osteoarthritic chondrocytes in situ by investigating the messenger RNA (mRNA) expression of 3 major cartilage components, type II collagen, aggrecan, and link protein. Methods. In situ hybridization exp

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::300085d637d7013171109ff7d4bea80d
https://doi.org/10.1002/art.1780400323

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Glomerular mesangial cells in vitro synthesize an aggregating proteoglycan immunologically related to versican

Autor: M T Bayliss, Roger M. Mason, K Harper, Gareth J. Thomas, Malcolm Davies

Publikováno v: Biochemical Journal. 302:49-56

Recent studies have shown that mesangial cells derived from human adult glomeruli synthesize a number of 35S-labelled proteoglycans including a large chondroitin sulphate proteoglycan (CSPG), two dermatan sulphate proteoglycans (biglycan and decorin)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5dc66679a29f367cabac68416af61b3c
https://doi.org/10.1042/bj3020049

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Expression of clusterin in the superficial zone of bovine articular cartilage

Autor: I M, Khan, D M, Salter, M T, Bayliss, B M, Thomson, C W, Archer

Publikováno v: Arthritis and rheumatism. 44(8)

To investigate the differences between chondrocytes of the superficial and underlying zones of articular cartilage at the level of gene expression.Messenger RNA (mRNA) was isolated from chondrocytes harvested from the superficial and deep zones of im

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::c853e663d5a4663506478b51089b28fe
https://pubmed.ncbi.nlm.nih.gov/11508431

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Matrix metalloproteinases and aggrecanases cleave aggrecan in different zones of normal cartilage but colocalize in the development of osteoarthritic lesions in STR/ort mice

Autor: M G, Chambers, L, Cox, L, Chong, N, Suri, P, Cover, M T, Bayliss, R M, Mason

Publikováno v: Arthritis and rheumatism. 44(6)

To map aggrecan cleavage by matrix metalloproteinases (MMPs) and aggrecanases in normal murine tibial articular cartilage (CBA strain) and in the development of spontaneous osteoarthritis (OA) in the STR/ort mouse and to assess the influence of sex h

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::2524ea62457f7114df8be6423c848a04
https://pubmed.ncbi.nlm.nih.gov/11407708

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Identification and characterization of asporin. a novel member of the leucine-rich repeat protein family closely related to decorin and biglycan

Autor: P, Lorenzo, A, Aspberg, P, Onnerfjord, M T, Bayliss, P J, Neame, D, Heinegard

Publikováno v: The Journal of biological chemistry. 276(15)

Asporin, a novel member of the leucine-rich repeat family of proteins, was partially purified from human articular cartilage and meniscus. Cloning of human and mouse asporin cDNAs revealed that the protein is closely related to decorin and biglycan.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::a5aeb928c2dee3a7e9f9bfb80154b3a6
https://pubmed.ncbi.nlm.nih.gov/11152692

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Autor: N, Verzijl, J, DeGroot, E, Oldehinkel, R A, Bank, S R, Thorpe, J W, Baynes, M T, Bayliss, J W, Bijlsma, F P, Lafeber, J M, Tekoppele

Publikováno v: The Biochemical journal.

Non-enzymic modification of tissue proteins by reducing sugars, the so-called Maillard reaction, is a prominent feature of aging. In articular cartilage, relatively high levels of the advanced glycation end product (AGE) pentosidine accumulate with a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::46279f4321f9c1b1ad0a357cce2d1c88
https://pubmed.ncbi.nlm.nih.gov/10947951

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