Zobrazeno 1 - 10
of 89
pro vyhledávání: '"M. T. Bahia"'
Autor:
M. T. Bahia, P. B. Da Silva, M. R. Simões-Silva, J. S. De Araújo, M. M. Batista, Mônica M. Bastos, Nubia Boechat, L D De Azevedo, Maria de Nazaré Correia Soeiro, Raiza Brandão Peres
Publikováno v:
Parasitology. 146(8)
Chagas disease (CD) is a neglected parasitic condition endemic in the Americas caused byTrypanosoma cruzi. Patients present an acute phase that may or not be symptomatic, followed by lifelong chronic stage, mostly indeterminate, or with cardiac and/o
Autor:
Abdelbasset A. Farahat, J. Green, Rubem F. S. Menna-Barreto, M. R. Simões-Silva, Maria de Nazaré Correia Soeiro, Arvind Kumar, A. S. G. Nefertiti, D. W. Boykin, J. S. De Araújo, P. B. Da Silva, M. M. F. Batista, M. T. Bahia, Beatriz Philot Pavão
Publikováno v:
Antimicrobial Agents and Chemotherapy. 60:4701-4707
The current treatment of Chagas disease (CD), based on nifurtimox and benznidazole (Bz), is unsatisfactory. In this context, we performed the phenotypic in vitro screening of novel mono- and diamidines and drug interaction assays with selected compou
Autor:
Camila Cardoso-Santos, Raiza Brandão Peres, D. G. J. Batista, C. F. Da Silva, J. S. De Araújo, M. R. Simões-Silva, Maria de Nazaré Correia Soeiro, P. B. Da Silva, I. D'Almeida-Melo, M. M. Batista, Gilkethyla Mexlayne de Oliveira, Kelly Cristina Demarque, M. T. Bahia
Publikováno v:
Biochemical pharmacology. 145
Metronidazole (Mtz) is a commercial broad-spectrum nitroimidazolic derivative with relevant antimicrobial activity and relative safety profile. Therefore, it is fair to consider Mtz a candidate for drug repurposing for other neglected conditions such
Autor:
Helen Rodrigues Martins, Olindo Assis Martins-Filho, M. de Lana, Wendel Coura-Vital, Washington Luiz Tafuri, Alexandre Barbosa Reis, Cláudia Martins Carneiro, Rodrigo Correa-Oliveira, M. T. Bahia, Vanja Maria Veloso, Andréa Teixeira-Carvalho
Publikováno v:
Experimental Parasitology. 120:269-274
A detailed investigation has been carried out about the serological profiles of groups of dogs experimentally infected with metacyclic (MT) or blood (BT) trypomastigotes of Berenice-78 Trypanosoma cruzi strain. Peripheral blood was collected from inf
Autor:
Max Jean de Ornelas Toledo, M. T. Bahia, Helder Magno Silva Valadares, Helen Rodrigues Martins, Vanja Maria Veloso, Andrea M. Macedo, Marta de Lana, R. Moreira Silva, D. M. Vitelli-Avelar, Olindo Assis Martins-Filho, George Luiz Lins Machado-Coelho, Cláudia Martins Carneiro
Publikováno v:
Antimicrobial Agents and Chemotherapy. 51:3282-3289
The aim of this work was to investigate the impact of dual infections with stocks ofTrypanosoma cruzimajor genotypes on benznidazole (BZ) treatment efficacy. For this purpose,T. cruzistocks representative of the geneticT. cruzilineages, displaying di
Autor:
M. T. Bahia, Maria Adelaide Do-Valle-Matta, Ivo Santana Caldas, Janeusa Trindade de Souto, Manuela Sales Lima Nascimento, Paulo Marcos da Matta Guedes, Álvaro Fernando da Silva do Nascimento, Antônia Cláudia Jácome da Câmara, T.D.R. Albuquerque, Lúcia Maria da Cunha Galvão, André Talvani
Publikováno v:
Journal of comparative pathology. 153(4)
Dogs are the primary urban reservoir of Leishmania infantum and play a crucial role in the transmission of this parasite to man via sandflies. The spleen and liver are the main target organs of L. infantum infection, but few studies have evaluated th
Autor:
Renzi G; NEUROFARBA Department, Pharmaceutical and Nutraceutical Section, University of Florence, Sesto Fiorentino, Italy., Ladu F; Department of Medicine, Surgery and Pharmacy, University of Sassari, Sassari, Italy., Carta F; NEUROFARBA Department, Pharmaceutical and Nutraceutical Section, University of Florence, Sesto Fiorentino, Italy., Supuran CT; NEUROFARBA Department, Pharmaceutical and Nutraceutical Section, University of Florence, Sesto Fiorentino, Italy.
Publikováno v:
Archiv der Pharmazie [Arch Pharm (Weinheim)] 2024 Nov 09, pp. e2400626. Date of Electronic Publication: 2024 Nov 09.
Autor:
Pedro Albajar-Viñas, Olindo Assis Martins-Filho, Marta de Lana, Girley Francisco Machado-de-Assis, João Carlos Pinto Dias, Ana Roberta Vilarouca da Silva, M. T. Bahia, Rosália Morais Torres, V. A. L. Do Bem
We performed a critical study of conventional serology, followed by supplementary serological, parasitological, and molecular tests, to assess the response to etiologic treatment of Chagas' disease. A group of 94 Chagas' disease patients treated with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05a74fd0b2edcda8273fa5019cb0ff68
https://europepmc.org/articles/PMC3416099/
https://europepmc.org/articles/PMC3416099/
Autor:
J. C. O. Valamiel-Silva, L. M. Figueiredo, Danielle Marquete Vitelli-Avelar, Olindo Assis Martins-Filho, Marta de Lana, Helen Rodrigues Martins, Andrea M. Macedo, M. T. Bahia, George Luiz Lins Machado-Coelho, Cláudia Martins Carneiro
Publikováno v:
The Journal of antimicrobial chemotherapy. 61(6)
Received 16 November 2007; returned 1 January 2008; revised 28 January 2008; accepted 12 February 2008Objectives: To assess different methodologies to better define an early post-therapeutic cure criterionafter benznidazole treatment in BALB/c mice
Autor:
Cláudia Martins Carneiro, Washington Luiz Tafuri, C. F. Alves, Vanja Maria Veloso, Marta de Lana, Egler Chiari, E. C. Borges, Alvaro J. Romanha, M. T. Bahia, Silvane M. F. Murta, George Luiz Lins Machado-Coelho
Publikováno v:
Parasitology research. 96(6)
The influence of the long-term Trypanosoma cruzi infection in vertebrate host on the biological and genetic properties of the parasite was evaluated. Four T. cruzi isolates obtained from different chronic chagasic dogs infected with Berenice-78 T. cr