Zobrazeno 1 - 10
of 926
pro vyhledávání: '"M. Stubbs"'
Autor:
Marc Jan Bonder, Stephen J. Clark, Felix Krueger, Siyuan Luo, João Agostinho de Sousa, Aida M. Hashtroud, Thomas M. Stubbs, Anne-Katrien Stark, Steffen Rulands, Oliver Stegle, Wolf Reik, Ferdinand von Meyenn
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract Ageing is the accumulation of changes and decline of function of organisms over time. The concept and biomarkers of biological age have been established, notably DNA methylation-based clocks. The emergence of single-cell DNA methylation prof
Externí odkaz:
https://doaj.org/article/ad7a8eed3efe49fdb4a325112b626eb9
Thrombotic thrombocytopenic purpura (TTP) is a rare disorder of the blood coagulation system. In most cases, a lack of the ADAMTS13 enzyme leads to an accumulation of ultra-large von Willebrand factor molecules in the plasma which, in turn, initiate
Autor:
Bradley L. Young, MD, Evan D. Sheppard, MD, Sierra Phillips, MD, Trevor M. Stubbs, MD, Jun Kit He, MD, Andrew Moon, MD, Martim C. Pinto, MD, Gerald McGwin, PhD, Eugene William Brabston, MD, Shawn R. Gilbert, MD, Brent A. Ponce, MD
Publikováno v:
JSES International, Vol 6, Iss 3, Pp 463-467 (2022)
Background: Tendon-to-bone (TtB) healing is essential for successful rotator cuff repair (RCR). This study aimed to investigate if caffeine intake impaired TtB healing in a rat RCR model. Methods: Seventy-two rats were randomized into a caffeinated g
Externí odkaz:
https://doaj.org/article/9b3d629dd94142bbb63bc4fbdb4039f0
Publikováno v:
BMC Health Services Research, Vol 21, Iss 1, Pp 1-12 (2021)
Abstract Background Most studies examining the psychological impact of COVID-19 on healthcare workers (HCWs) have assessed well-being during the initial stages or the peak of the first wave of the pandemic. We aimed to measure the impact of COVID-19
Externí odkaz:
https://doaj.org/article/e471bcaba7b24441964a2b8fdb4c9d4c
Autor:
Joanne M. Stubbs, Helen M. Achat
Publikováno v:
Psychiatry Research Communications, Vol 2, Iss 2, Pp 100050- (2022)
Loneliness is a major public health issue with renewed prominence due to the COVID-19 pandemic and associated social restrictions. Healthcare workers (HCWs) may be at heightened risk, but research is lacking. We measured the prevalence of loneliness
Externí odkaz:
https://doaj.org/article/0989fb9e1cff4baba9c64a7aeab13871
Autor:
Diljeet Gill, Aled Parry, Fátima Santos, Hanneke Okkenhaug, Christopher D Todd, Irene Hernando-Herraez, Thomas M Stubbs, Inês Milagre, Wolf Reik
Publikováno v:
eLife, Vol 11 (2022)
Ageing is the gradual decline in organismal fitness that occurs over time leading to tissue dysfunction and disease. At the cellular level, ageing is associated with reduced function, altered gene expression and a perturbed epigenome. Recent work has
Externí odkaz:
https://doaj.org/article/022f5dca919f4be9a3868d80779d1d2f
Autor:
Helen M Achat, Rakhi Mittal, Joanne M Stubbs, Nicky Gilroy, Suzanne K Schindeler, Ramon Z Shaban, Thomas Solano
Publikováno v:
PLoS ONE, Vol 17, Iss 12, p e0278479 (2022)
Health care workers' (HCWs) lived experiences and perceptions of the pandemic can prove to be a valuable resource in the face of a seemingly persistent Novel coronavirus disease 2019 (COVID-19)-to inform ongoing efforts, as well as identify component
Externí odkaz:
https://doaj.org/article/088a99249d25480aa2f5e9475e3cc3dd
Publikováno v:
Australian and New Zealand Journal of Public Health, Vol 46, Iss 1, Pp 95-96 (2022)
Externí odkaz:
https://doaj.org/article/6841e64da6f445e3aec66fddf842bdbc
Autor:
Daniel E. Martin-Herranz, Erfan Aref-Eshghi, Marc Jan Bonder, Thomas M. Stubbs, Sanaa Choufani, Rosanna Weksberg, Oliver Stegle, Bekim Sadikovic, Wolf Reik, Janet M. Thornton
Publikováno v:
Genome Biology, Vol 20, Iss 1, Pp 1-19 (2019)
Abstract Background Epigenetic clocks are mathematical models that predict the biological age of an individual using DNA methylation data and have emerged in the last few years as the most accurate biomarkers of the aging process. However, little is
Externí odkaz:
https://doaj.org/article/cd20924a14ee4e9ab07216a2bfff971e
Publikováno v:
Synlett. 34:445-450
A group of thirteen catalysts of type [Ru(Cp/Cp*)(P–P)(MeCN)]PF6, bearing cooperative or noncooperative bidentate phosphine ligands, were evaluated for the catalytic acceptorless dehydrogenation of indoline. The systematic comparison revealed that