Zobrazeno 1 - 10
of 167
pro vyhledávání: '"M. Steyer"'
Autor:
Anika Hintze, Felix Lange, Anna M. Steyer, Jannis Anstatt, Wiebke Möbius, Stefan Jakobs, Carolin Wichmann
Publikováno v:
iScience, Vol 27, Iss 1, Pp 108700- (2024)
Summary: Mitochondria are key organelles to provide ATP for synaptic transmission. This study aims to unravel the structural adaptation of mitochondria to an increase in presynaptic energy demand and upon the functional impairment of the auditory sys
Externí odkaz:
https://doaj.org/article/4018229c21504a338f1074f27baf3189
Autor:
Susann Michanski, Timo Henneck, Mohona Mukhopadhyay, Anna M. Steyer, Paola Agüi Gonzalez, Katharina Grewe, Peter Ilgen, Mehmet Gültas, Eugenio F. Fornasiero, Stefan Jakobs, Wiebke Möbius, Christian Vogl, Tina Pangršič, Silvio O. Rizzoli, Carolin Wichmann
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 11 (2023)
In mammals, spatial orientation is synaptically-encoded by sensory hair cells of the vestibular labyrinth. Vestibular hair cells (VHCs) harbor synaptic ribbons at their presynaptic active zones (AZs), which play a critical role in molecular scaffoldi
Externí odkaz:
https://doaj.org/article/8a082d64aed74a27b28bba0e37aa706b
Autor:
Martin Meschkat, Anna M. Steyer, Marie-Theres Weil, Kathrin Kusch, Olaf Jahn, Lars Piepkorn, Paola Agüi-Gonzalez, Nhu Thi Ngoc Phan, Torben Ruhwedel, Boguslawa Sadowski, Silvio O. Rizzoli, Hauke B. Werner, Hannelore Ehrenreich, Klaus-Armin Nave, Wiebke Möbius
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-18 (2022)
Myelin is formed of proteins of long half-lives. The mechanisms of renewal of such a stable structure are unclear. Here, the authors show that myelin integrity requires continuous myelin synthesis at the inner tongue, contributing to the maintenance
Externí odkaz:
https://doaj.org/article/287e7feee643483fbef3a7725df08a2f
Autor:
Tobias J Buscham, Maria A Eichel-Vogel, Anna M Steyer, Olaf Jahn, Nicola Strenzke, Rakshit Dardawal, Tor R Memhave, Sophie B Siems, Christina Müller, Martin Meschkat, Ting Sun, Torben Ruhwedel, Wiebke Möbius, Eva-Maria Krämer-Albers, Susann Boretius, Klaus-Armin Nave, Hauke B Werner
Publikováno v:
eLife, Vol 11 (2022)
Oligodendrocytes facilitate rapid impulse propagation along the axons they myelinate and support their long-term integrity. However, the functional relevance of many myelin proteins has remained unknown. Here, we find that expression of the tetraspan
Externí odkaz:
https://doaj.org/article/f7b1fb656ccc4da5be331128cb894c52
Autor:
Philippe Jean, Tommi Anttonen, Susann Michanski, Antonio M. G. de Diego, Anna M. Steyer, Andreas Neef, David Oestreicher, Jana Kroll, Christos Nardis, Tina Pangršič, Wiebke Möbius, Jonathan Ashmore, Carolin Wichmann, Tobias Moser
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
The inner hair cells (IHCs) within the cochlea convey sound information and have been thought to be electrically and metabolically independent from each other. Here authors report that a subset of IHCs are electrochemically coupled in ‘mini-syncyti
Externí odkaz:
https://doaj.org/article/46d16b11f8924be9985d3d1236057b1d
Autor:
Andrea Trevisiol, Kathrin Kusch, Anna M Steyer, Ingo Gregor, Christos Nardis, Ulrike Winkler, Susanne Köhler, Alejandro Restrepo, Wiebke Möbius, Hauke B Werner, Klaus-Armin Nave, Johannes Hirrlinger
Publikováno v:
PLoS Biology, Vol 18, Iss 11, p e3000943 (2020)
In several neurodegenerative disorders, axonal pathology may originate from impaired oligodendrocyte-to-axon support of energy substrates. We previously established transgenic mice that allow measuring axonal ATP levels in electrically active optic n
Externí odkaz:
https://doaj.org/article/61c88fbc528c462a986b38a93992e117
Autor:
Michelle S Erwig, Julia Patzig, Anna M Steyer, Payam Dibaj, Mareike Heilmann, Ingo Heilmann, Ramona B Jung, Kathrin Kusch, Wiebke Möbius, Olaf Jahn, Klaus-Armin Nave, Hauke B Werner
Publikováno v:
eLife, Vol 8 (2019)
Myelin serves as an axonal insulator that facilitates rapid nerve conduction along axons. By transmission electron microscopy, a healthy myelin sheath comprises compacted membrane layers spiraling around the cross-sectioned axon. Previously we identi
Externí odkaz:
https://doaj.org/article/7c7f991aa71d4f31b9327cfa70377a73
Autor:
José M. Serra Lleti, Anna M. Steyer, Nicole L. Schieber, Beate Neumann, Christian Tischer, Volker Hilsenstein, Mike Holtstrom, David Unrau, Robert Kirmse, John M. Lucocq, Rainer Pepperkok, Yannick Schwab
Correlative light and electron microscopy (CLEM) combines two imaging modalities, balancing out the limits of one technique with the other. In recent years, Focused Ion Beam Scanning Electron Microscopy (FIB-SEM) has emerged as a flexible method that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e793fe6fb6c100e350788e6727df7fb
https://hdl.handle.net/10023/26798
https://hdl.handle.net/10023/26798
Autor:
Anna M. Steyer, Tobias J. Buscham, Charlotta Lorenz, Sophie Hümmert, Maria A. Eichel‐Vogel, Leonie C. Schadt, Julia M. Edgar, Sarah Köster, Wiebke Möbius, Klaus‐Armin Nave, Hauke B. Werner
Publikováno v:
Glia. 71
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::39cfec2d027be2e7a425c4a0b22834b6
https://doi.org/10.1002/glia.24198
https://doi.org/10.1002/glia.24198
Autor:
Susann Michanski, Timo Henneck, Mohona Mukhopadhyay, Anna M. Steyer, Paola Agüi Gonzalez, Katharina Grewe, Peter Ilgen, Mehmet Gültas, Eugenio F. Fornasiero, Stefan Jakobs, Wiebke Möbius, Christian Vogl, Tina Pangršič, Silvio O. Rizzoli, Carolin Wichmann
In mammals, spatial orientation is synaptically-encoded by sensory hair cells of the vestibular labyrinth. Vestibular hair cells (VHCs) harbor synaptic ribbons at their presynaptic active zones (AZs), which play a critical role in molecular scaffoldi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3c3e3bb930cc2f1419480c3c7b02e174
https://doi.org/10.1101/2022.12.19.521049
https://doi.org/10.1101/2022.12.19.521049