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Akademický článek

In vitro and in vivo Characterization of Host–Pathogen Interactions of the L3881 Candida albicans Clinical Isolate

Autor: Pedro H. F. Sucupira, Tauany R. Moura, Isabella L. S. Gurgel, Tassia T. P. Pereira, Ana C. B. Padovan, Mauro M. Teixeira, Diana Bahia, Frederico M. Soriani

Publikováno v: Frontiers in Microbiology, Vol 13 (2022)

Candida albicans is a human commensal fungus and the etiologic agent of nosocomial infections in immunocompromised individuals. Candida spp. is the most studied human fungal pathogen, and the mechanisms by which this fungus can evade the immune syste

Externí odkaz: https://doaj.org/article/ced8c0e5ccc14a28bddf86a1a86b8d11

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Akademický článek

In-depth characterization of congenital Zika syndrome in immunocompetent mice: Antibody-dependent enhancement and an antiviral peptide therapyResearch in context

Publikováno v: EBioMedicine, Vol 44, Iss , Pp 516-529 (2019)

Background: Zika virus (ZIKV) infection during pregnancy may cause major congenital defects, including microcephaly, ocular, articular and muscle abnormalities, which are collectively defined as Congenital Zika Syndrome. Here, we performed an in-dept

Externí odkaz: https://doaj.org/article/e0923c43a6294b3c8e399dd439520bd5

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Akademický článek

Histologic and inflammatory lamellar changes in horses with oligofructose-induced laminitis treated with a CXCR1/2 antagonist

Autor: Leonardo R. de Lima, Heloisa M.F. Mendes, Frederico M. Soriani, Danielle G. de Souza, Geraldo Eleno S. Alves, Mauro M. Teixeira, Rafael R. Faleiros

Publikováno v: Pesquisa Veterinária Brasileira, Vol 36, Iss 1, Pp 13-18 (2016)

Abstract: With the hypothesis that blocking chemokine signaling can ameliorate acute laminitis, the aim was to evaluate the therapeutic effect of intravenous DF1681B, a selective antagonist for CXCR1 and CXCR2 (chemokine receptors), in an oligofructo

Externí odkaz: https://doaj.org/article/0ed79ddd88b944329e40121f6c6ca169

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Akademický článek

Phosphatidyl Inositol 3 Kinase-Gamma Balances Antiviral and Inflammatory Responses During Influenza A H1N1 Infection: From Murine Model to Genetic Association in Patients

Autor: Cristiana C. Garcia, Luciana P. Tavares, Ana Carolina F. Dias, Fernanda Kehdy, Lucia Elena Alvarado-Arnez, Celso M. Queiroz-Junior, Izabela Galvão, Braulio H. Lima, Aline R. Matos, Ana Paula F. Gonçalves, Frederico M. Soriani, Milton O. Moraes, João T. Marques, Marilda M. Siqueira, Alexandre M. V. Machado, Lirlândia P. Sousa, Remo C. Russo, Mauro M. Teixeira

Publikováno v: Frontiers in Immunology, Vol 9 (2018)

Influenza A virus (IAV) infection causes severe pulmonary disease characterized by intense leukocyte infiltration. Phosphoinositide-3 kinases (PI3Ks) are central signaling enzymes, involved in cell growth, survival, and migration. Class IB PI3K or ph

Externí odkaz: https://doaj.org/article/926379fd93c44a8a9a99d8bd0e10d476

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Akademický článek

Candida albicans: The Ability to Invade Epithelial Cells and Survive under Oxidative Stress Is Unlinked to Hyphal Length

Autor: Paloma K. Maza, Alexis Bonfim-Melo, Ana C. B. Padovan, Renato A. Mortara, Cristina M. Orikaza, Lilian M. Damas Ramos, Tauany R. Moura, Frederico M. Soriani, Ricardo S. Almeida, Erika Suzuki, Diana Bahia

Publikováno v: Frontiers in Microbiology, Vol 8 (2017)

In its hyphal form, Candida albicans invades epithelial and endothelial cells by two distinct mechanisms: active penetration and induced endocytosis. The latter is dependent on a reorganization of the host cytoskeleton (actin/cortactin recruitment),

Externí odkaz: https://doaj.org/article/11682436f18a432b8a83adaf341d046b

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Akademický článek

Annexin A1 Is Increased in the Plasma of Preeclamptic Women.

Autor: Luiza O Perucci, Fernanda S Carneiro, Cláudia N Ferreira, Michelle A Sugimoto, Frederico M Soriani, Gustavo G Martins, Kátia M Lima, Flávia L Guimarães, Antônio L Teixeira, Luci M Dusse, Karina B Gomes, Lirlândia P Sousa

Publikováno v: PLoS ONE, Vol 10, Iss 9, p e0138475 (2015)

Preeclampsia (PE) is a pregnancy disease associated with exacerbated inflammatory response. Annexin A1 (AnxA1) is a glucocorticoid-regulated protein endowed with anti-inflammatory and proresolving properties that has been much studied in various anim

Externí odkaz: https://doaj.org/article/b46d1cb27f214acaad61a9abde17902b

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