Zobrazeno 1 - 10 of 11 pro vyhledávání: '"M. Soledad Fernández-García"'
1
Akademický článek
ATP-Dependent Lon Protease Controls Tumor Bioenergetics by Reprogramming Mitochondrial Activity
Autor: Pedro M. Quirós, Yaiza Español, Rebeca Acín-Pérez, Francisco Rodríguez, Clea Bárcena, Kenta Watanabe, Enrique Calvo, Marta Loureiro, M. Soledad Fernández-García, Antonio Fueyo, Jesús Vázquez, José Antonio Enríquez, Carlos López-Otín
Publikováno v: Cell Reports, Vol 8, Iss 2, Pp 542-556 (2014)
We generated mice deficient in Lon protease (LONP1), a major enzyme of the mitochondrial quality control machinery. Homozygous deletion of Lonp1 causes early embryonic lethality, whereas its haploinsufficiency protects against colorectal and skin tum
Externí odkaz: https://doaj.org/article/c628e3a772344fb6bec50e4f632d1921
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2
Frequent Alteration of Annexin A9 and A10 in HPV-Negative Head and Neck Squamous Cell Carcinomas: Correlation with the Histopathological Differentiation Grade
Autor: Aitana Vallina, Eva Allonca, Juan P. Rodrigo, Corina Lorz, M. Pilar Fernandez, Juana M. García-Pedrero, Saúl Álvarez-Teijeiro, Lucas de Villalaín, M. Soledad Fernández-García, Reginald O. Morgan, Cecilia Salom
Publikováno v: WOS:000460295400102
RUO. Repositorio Institucional de la Universidad de Oviedo
instname
Journal of Clinical Medicine
Volume 8
Issue 2
Journal of Clinical Medicine, Vol 8, Iss 2, p 229 (2019)
The annexin protein superfamily has been implicated in multiple physiological and pathological processes, including carcinogenesis. Altered expression of various annexins has frequently been observed and linked to the development and progression of v
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08a98e3a7963ca3a347c62887566f542
http://hdl.handle.net/10651/52416
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3
The Novel Role of SOX2 as an Early Predictor of Cancer Risk in Patients with Laryngeal Precancerous Lesions
Autor: Mario Sánchez-Canteli, Sofía T. Menéndez, Rocío Granda-Díaz, Rene Rodriguez, Daniel Pedregal Mallo, Laura Suárez-Fernández, Aitana Vallina, M. Soledad Fernández-García, Francisco Hermida-Prado, Juan P. Rodrigo, Aida Rodríguez, Juana M. García-Pedrero
Publikováno v: Cancers
Volume 11
Issue 3
Scopus
RUO. Repositorio Institucional de la Universidad de Oviedo
instname
Cancers, Vol 11, Iss 3, p 286 (2019)
The SOX2 gene located at 3q26 is frequently amplified and overexpressed in multiple cancers, including head and neck squamous cell carcinomas (HNSCC). The tumor-promoting activity and involvement of SOX2 in tumor progression has been extensively demo
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00e1ff0f36806f1ea336f9a64a85adb1
https://doi.org/10.3390/cancers11030286
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4
Matrix Metalloproteinase Mmp-1a Is Dispensable for Normal Growth and Fertility in Mice and Promotes Lung Cancer Progression by Modulating Inflammatory Responses
Autor: Antonio Fueyo, Miriam Fanjul-Fernández, Carlos López-Otín, José M.P. Freije, M. Soledad Fernández-García, Steven D. Shapiro, Alicia R. Folgueras, Milagros Balbín, María F. Suárez
Publikováno v: Journal of Biological Chemistry. 288:14647-14656
Human MMP-1 is a matrix metalloproteinase repeatedly associated with many pathological conditions, including cancer. Thus, MMP1 overexpression is a poor prognosis marker in a variety of advanced cancers, including colorectal, breast, and lung carcino
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b99cc65d87b33c15e396f7d7d33df73
https://doi.org/10.1074/jbc.m112.439893
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5
MMP-25 Metalloprotease Regulates Innate Immune Response through NF-κB Signaling
Autor: Fernando G. Osorio, M. Soledad Fernández-García, Ana Gutiérrez-Fernández, Elena Bonzón-Kulichenko, Jesús Vázquez, Antonio Fueyo, Enrique Colado, Carlos López-Otín, Dido Carrero, Adolfo A. Ferrando, Clara Soria-Valles
Publikováno v: Journal of immunology (Baltimore, Md. : 1950). 197(1)
Matrix metalloproteases (MMPs) regulate innate immunity acting over proinflammatory cytokines, chemokines, and other immune-related proteins. MMP-25 (membrane-type 6-MMP) is a membrane-bound enzyme predominantly expressed in leukocytes whose biologic
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40c4762c6f3e7b59b6bdb19626cd246b
https://pubmed.ncbi.nlm.nih.gov/27259858
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6
The diagnosis and treatment of dyskeratosis congenita: a review
Autor: Julie Teruya-Feldstein, M Soledad Fernández García
Publikováno v: Journal of Blood Medicine
Dyskeratosis congenita (DC) is an inherited bone marrow failure (BMF) syndrome characterized by the classic triad of abnormal skin pigmentation, nail dystrophy, and oral leukoplakia. However, patients usually develop BMF and are predisposed to cancer
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c10cfe918ab4744a438dda6b95cd365f
https://pubmed.ncbi.nlm.nih.gov/25170286
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7
ATP-dependent Lon protease controls tumor bioenergetics by reprogramming mitochondrial activity
Autor: Clea Bárcena, Enrique Calvo, Kenta Watanabe, Rebeca Acín-Pérez, Pedro M. Quirós, Marta Loureiro, Yaiza Español, Antonio Fueyo, M. Soledad Fernández-García, Carlos López-Otín, José Antonio Enríquez, Jesús Vázquez, Francisco Rodríguez
Publikováno v: Scopus
RUO. Repositorio Institucional de la Universidad de Oviedo
instname
Cell Reports, Vol 8, Iss 2, Pp 542-556 (2014)
Repisalud
Instituto de Salud Carlos III (ISCIII)
We generated mice deficient in Lon protease (LONP1), a major enzyme of the mitochondrial quality control machinery. Homozygous deletion of Lonp1 causes early embryonic lethality, whereas its haploinsufficiency protects against colorectal and skin tum
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6fdf0f80858f65987296dbabc51c8d14
https://pubmed.ncbi.nlm.nih.gov/25017063
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8
Prelamin A causes progeria through cell-extrinsic mechanisms and prevents cancer invasion
Autor: Mario F. Fraga, Rubén Cabanillas, Fernando G. Osorio, Jorge de la Rosa, Juan Cadiñanos, M. Soledad Fernández-García, Allan Bradley, Haydn M. Prosser, Alejandro P. Ugalde, Qi Liang, Víctor Fanjul, José M.P. Freije, Carlos López-Otín, Roland Rad
Publikováno v: Nature communications
WOK
RUO. Repositorio Institucional de la Universidad de Oviedo
instname
Defining the relationship between ageing and cancer is a crucial but challenging task. Mice deficient in Zmpste24, a metalloproteinase mutated in human progeria and involved in nuclear prelamin A maturation, recapitulate multiple features of ageing.
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1186a93e8c3a453ce5f036cc20c5c304
https://www.repository.cam.ac.uk/handle/1810/311511
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9
ATG4B/autophagin-1 regulates intestinal homeostasis and protects mice from experimental colitis
Autor: Álvaro F. Fernández, Rosaria Laurà, María F. Suárez, José M.P. Freije, Guillermo Mariño, Antonio Fueyo, M. Soledad Fernández-García, Carlos López-Otín, Sandra Cabrera, Guido Kroemer, Alina Aguirre, José A. Vega, Yaiza Español
Publikováno v: SCOPUS
RUO. Repositorio Institucional de la Universidad de Oviedo
instname
The identification of inflammatory bowel disease (IBD) susceptibility genes by genome-wide association has linked this pathology to autophagy, a lysosomal degradation pathway that is crucial for cell and tissue homeostasis. Here, we describe autophag
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1140fc6a330b623a5b280a3d13464d7a
http://hdl.handle.net/10651/19762
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10
Akademický článek
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