Zobrazeno 1 - 10
of 27
pro vyhledávání: '"M. Sirac Dilber"'
Autor:
Birgitta Stellan, Tolga Sutlu, Birger Christensson, Evren Alici, Hayrettin Guven, Réka Conrad, Eva Kimby, L Barkholt, M. Sirac Dilber, Gunnar Söderdahl, Niklas K. Björkström, Olle Ringdén, Hans-Gustaf Ljunggren, Mari Gilljam, Kerstin Cederlund, J. Aschan
Publikováno v:
Immunotherapy. 1:753-764
The chimeric state after allogeneic hematopoietic stem cell transplantation provides a platform for adoptive immunotherapy using donor-derived immune cells. The major risk with donor lymphocyte infusions (DLIs) is the development of graft-versus-host
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ff6c3debe69a0d505621b0b7498ce6d
https://doi.org/10.2217/imt.09.47
https://doi.org/10.2217/imt.09.47
Publikováno v:
Human Molecular Genetics. 17:R48-R53
Human embryonic stem cell (hESC) lines, after directed differentiation, hold the greatest potential for cell transplantation treatment in many severe diseases. Good manufacturing practice (GMP) quality, defined by both the European Medicines Agency a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9fa2788e0c503192a9ef0ab2dfdfcf75
https://doi.org/10.1093/hmg/ddn079
https://doi.org/10.1093/hmg/ddn079
Autor:
Birgitta Stellan, Tolga Sutlu, M. Sirac Dilber, Evren Alici, Hareth Nahi, Mari Gilljam, Bo Björkstrand, Hans-Gustaf Ljunggren, Gösta Gahrton, Hernan Concha Quezada
Publikováno v:
Blood. 111:3155-3162
Multiple myeloma (MM) is an incurable plasma cell malignancy with poor outcome. The most promising therapeutic options currently available are combinations of transplantation, targeted pharmacotherapy, and immunotherapy. Cell-based immunotherapy afte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::efae796d2feaf2a954a516938578a929
https://doi.org/10.1182/blood-2007-09-110312
https://doi.org/10.1182/blood-2007-09-110312
Autor:
Tolga Sutlu, Alar Aints, Hans-Gustaf Ljunggren, Gösta Gahrton, Kyriakos V. Konstantinidis, Evren Alici, M. Sirac Dilber
Publikováno v:
Experimental Hematology. 35:1839-1846
Objective Despite advances in autologous stem cell transplantation and chemotherapy, multiple myeloma (MM) remains an incurable disease. Due to the role of natural killer (NK) cells in host resistance against several tumors, it is of interest to expl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d4bd4217268825318ea6dd0b9e0140d
https://doi.org/10.1016/j.exphem.2007.08.006
https://doi.org/10.1016/j.exphem.2007.08.006
Autor:
Iulian I Oprea, H. Jose Arteaga, Gösta Gahrton, M. Sirac Dilber, Maria E. Cardona, Birger Christensson, Oscar E. Simonson, Maria F Silva-Lara, Abdalla J. Mohamed, Pedro Moreno, C. I. Edvard Smith
Publikováno v:
Leukemialymphoma. 57(1)
The poor treatment response of acute myeloid leukemia (AML) overexpressing high-risk oncogenes such as EVI1, demands specific animal models for new treatment evaluations. Evi1 is a common site of activating integrations in murine leukemia virus (MLV)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b661eb5dc1b21f4b9b1f476425a1a0c1
https://pubmed.ncbi.nlm.nih.gov/25907616
https://pubmed.ncbi.nlm.nih.gov/25907616
Autor:
Kyriakos V. Konstantinidis, Alar Aints, Hans-Gustaf Ljunggren, Manuchehr Abedi-Valugerdi, Evren Alici, M. Sirac Dilber, Hayrettin Guven, Birger Christensson
Publikováno v:
Experimental Hematology. 33:1320-1328
Objective To optimize retroviral gene transfer into primary human natural killer (NK) cells. Materials and methods NK cells from healthy donors were expanded ex vivo for a period of 21 days. Retroviral transductions were carried out by replacing cult
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b15721379410010f19fc049b45a2f1b
https://doi.org/10.1016/j.exphem.2005.07.006
https://doi.org/10.1016/j.exphem.2005.07.006
Autor:
Alar Aints, M. Sirac Dilber, Evren Alici, Birger Christensson, Hans-Gustaf Ljunggren, Kyriakos V. Konstantinidis
Publikováno v:
Experimental Hematology. 33:159-164
Objective Anti-tumor effects mediated by adoptively transferred natural killer (NK) cells are dependent on the presence of interleukin-2 (IL-2). IL-2 is considered to be a survival factor for NK cells and an enhancer of their cytotoxic potential. How
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab00478f9cefa280e005bdf8cdebc7f5
https://doi.org/10.1016/j.exphem.2004.11.003
https://doi.org/10.1016/j.exphem.2004.11.003
Publikováno v:
Experimental Hematology. 28:1137-1146
Objective In the setting of allogeneic stem cell transplantation, suicide gene-manipulated donor T cells that can be selectively inactivated in vivo would potentially allow optimal control of the GVL (graft-vs-leukemia)/GVHD (graft-vs-host disease) b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2b916e799affd011fda4456d16993e99
https://doi.org/10.1016/s0301-472x(00)00526-9
https://doi.org/10.1016/s0301-472x(00)00526-9
Autor:
Kristoffer Weber, Ulrika Felldin, Evren Alici, Daniela Brücher, Ellen Preuß, M. Sirac Dilber, Sebastian Newrzela, Boris Fehse, Alexandra Treschow, Dorothee von Laer, Gösta Gahrton
Publikováno v:
Human gene therapy. 21(8)
Conditional elimination of infused gene-modified alloreactive T cells, using suicide gene activation, has been shown to be an efficient strategy to abrogate severe graft-versus-host disease (GvHD) in the context of adoptive immunotherapy. To overcome
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2502c9316d314bcbe9c16bfb89ab063e
https://pubmed.ncbi.nlm.nih.gov/20201626
https://pubmed.ncbi.nlm.nih.gov/20201626
Publikováno v:
Genetic Modification of Hematopoietic Stem Cells ISBN: 9781588299802
Modulation of intracellular signaling pathways or receptor expression in natural killer (NK) cells by genetic manipulation is an attractive possibility in studies of NK cell specificity and function. Moreover, feasible applications of these genetic m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::77f706d73daad40bdcd5c81ef5847377
https://doi.org/10.1007/978-1-59745-409-4_10
https://doi.org/10.1007/978-1-59745-409-4_10
