Zobrazeno 1 - 10
of 33
pro vyhledávání: '"M. Shawkat Razzaque"'
Autor:
M. Shawkat Razzaque
Publikováno v:
Nature Reviews Endocrinology. 8:579-587
A disproportionate expansion of white adipose tissue and abnormal recruitment of adipogenic precursor cells can not only lead to obesity but also impair glucose metabolism, which are both common causes of insulin resistance and diabetes mellitus. The
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99e1de0c3c2874d69c6affe52759f534
https://doi.org/10.1038/nrendo.2012.75
https://doi.org/10.1038/nrendo.2012.75
Autor:
M. Shawkat Razzaque
Publikováno v:
Kidney International. 79:708-714
Vitamin D is a multifunctional hormone that can affect many essential biological functions, ranging from the immune regulation to mineral ion metabolism. A close association between altered activity of vitamin D and vascular calcification has been re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7538b4c8dbe979243bd30c7a61f47ab9
https://doi.org/10.1038/ki.2010.432
https://doi.org/10.1038/ki.2010.432
Autor:
M. Shawkat Razzaque, Mutsuko Ohnishi
Publikováno v:
The FASEB Journal. 24:3562-3571
Identifying factors that accelerate the aging process can provide important therapeutic targets for slowing down this process. Misregulation of phosphate homeostasis has been noted in various skeletal, cardiac, and renal diseases, but the exact role
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f94c1b2df99e3433ef3a24c711e91ce
https://doi.org/10.1096/fj.09-152488
https://doi.org/10.1096/fj.09-152488
Publikováno v:
Circulation: Cardiovascular Genetics. 2:583-590
Background— Klotho -knockout mice ( klotho −/− ) have increased renal expression of sodium/phosphate cotransporters (NaPi2a), associated with severe hyperphosphatemia. Such serum biochemical changes in klotho −/− mice lead to extensive soft
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f8e0f353b3978b6f0333ac58f36bfbe8
https://doi.org/10.1161/circgenetics.108.847814
https://doi.org/10.1161/circgenetics.108.847814
Autor:
M. Shawkat Razzaque
Publikováno v:
Nature Reviews Endocrinology. 5:611-619
Appropriate levels of phosphate in the body are maintained by the coordinated regulation of the bone-derived growth factor FGF23 and the membrane-bound protein Klotho. The endocrine actions of FGF23, in association with parathyroid hormone and vitami
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db70d10928e529076a3aa584bf45c184
https://doi.org/10.1038/nrendo.2009.196
https://doi.org/10.1038/nrendo.2009.196
Publikováno v:
The FASEB Journal. 23:3702-3711
Hyp mice possess a mutation that inactivates the phosphate-regulating gene, which is homologous to the endopeptidases of the X-chromosome (PHEX). The mutation is associated with severe hypophosphatemia due to excessive urinary phosphate wasting. Such
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b65f774f9c0d776526069f4bc429627
https://doi.org/10.1096/fj.08-123992
https://doi.org/10.1096/fj.08-123992
Autor:
M. Shawkat Razzaque, Yoshikazu Higami, Arifa Nazneen, Isao Shimokawa, Takashi Taguchi, Yan Zha
Publikováno v:
American Journal of Nephrology. 28:755-764
Aim: The aim of this study was to determine the effects of kidney pathology on overall survival and longevity and the combined effects of chronic suppression of growth hormone (GH)/insulin-like growth factor-1 (IGF-1) activity and lifelong caloric re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::afa783a46d8edb3f816dd836afaaf084
https://doi.org/10.1159/000128607
https://doi.org/10.1159/000128607
Publikováno v:
American Journal of Nephrology. 28:555-568
Background: Crescentic glomerulonephritis is a rapidly progressive form of nephritis and is usually resistant to therapeutic intervention. Apoptosis plays a role in the resolution of glomerulonephritis. We investigated the effects of local kidney irr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3bfd34f3dd20400e5a988668ac903b38
https://doi.org/10.1159/000115290
https://doi.org/10.1159/000115290
Autor:
M. Shawkat Razzaque, Beate Lanske
Publikováno v:
Current Opinion in Nephrology & Hypertension. 16:311-318
Purpose of review—Our understanding of the regulation of mineral ion homeostasis is rather stagnant, and until recently the regulation of phosphate homeostasis was thought to be a passive process mediated largely by the well known calciotrophic hor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::703f1ad6958089beefc156aef97c7398
https://doi.org/10.1097/mnh.0b013e3281c55eca
https://doi.org/10.1097/mnh.0b013e3281c55eca
Autor:
M. Shawkat Razzaque
Publikováno v:
Nephrology Dialysis Transplantation. 22:2112-2116
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e122e4a3dd79d5c578ae1cae34cca76d
https://doi.org/10.1093/ndt/gfm378
https://doi.org/10.1093/ndt/gfm378