Zobrazeno 1 - 10
of 51
pro vyhledávání: '"M. Seibert-Grafe"'
Publikováno v:
Bundesgesundheitsblatt - Gesundheitsforschung - Gesundheitsschutz. 52:444-450
Coordination Centres for Clinical Trials (Koordinierungszentren fur Klinische Studien, KKS) were set up to increase the quality and number of clinical trials in Germany as well as to establish clinical trial training programs in order to improve inte
Autor:
D. Heger-Mahn, K. Breithaupt-Grögler, M. Mahler, Robert Hermann, C. Klipping, C. de Mey, M. Seibert-Grafe
Publikováno v:
European Journal of Clinical Pharmacology. 53:207-214
Objective: The various good clinical practice (GCP) guidelines do not define the volunteering subject as an active party. The present survey addresses the volunteer's perception of study-related inconvenience and risk and its impact on their decision
Autor:
Adam F. Cohen, H. J. Röthig, H. G. Luus, M. Seibert-Grafe, Rik C. Schoemaker, J. M. T. Van Griensven
Publikováno v:
European Journal of Clinical Pharmacology. 47:513-518
The pharmacokinetics and pharmacodynamics of the prodrug ramipril and its active ACE-inhibiting metabolite ramiprilat were investigated in an open, randomised, three-way cross-over study in 12 healthy male volunteers. Subjects received 2.5 mg ramipri
Autor:
A M, Joussen, D, Wong, P, Walter, B, Kirchhof, J, Dreyhaupt, C, Bauer, J, Munzinger, K, Unnebrink, A, Freiberger, M, Seibert-Grafe, N, Victor, Elizabeth, Garnett
Publikováno v:
Eye (London, England). 24(2)
The MARAN (Macular Relocation in Age-related Neovascular disease) trial was planned to assess the effectiveness of full macular relocation (MR) in patients with neovascular age-related macular degeneration (AMD).Randomised, prospective, controlled cl
Publikováno v:
Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz. 52(4)
Coordination Centres for Clinical Trials (Koordinierungszentren für Klinische Studien, KKS) were set up to increase the quality and number of clinical trials in Germany as well as to establish clinical trial training programs in order to improve int
Autor:
M Seibert-Grafe
Publikováno v:
RöFo - Fortschritte auf dem Gebiet der Röntgenstrahlen und der bildgebenden Verfahren. 176
Autor:
H. E.K Scholtz, H. G. Luus, F. O. Müller, M. Seibert-Grafe, N. de la Rey, B. H. Meyer, H. G. Eckert, H. Metzger
Publikováno v:
European Journal of Clinical Pharmacology. 47:373-375
Twenty two healthy males participated in a randomised, placebo-controlled, double blind, cross-over study to investigate the influence of simvastatin on the pharmacokinetics of ramipril and its active metabolite (ramiprilat), and on the ACE-inhibitin
Autor:
R, Hermann, D, Heger-Mahn, M, Mahler, M, Seibert-Grafe, C, Klipping, K, Breithaupt-Grögler, C, de Mey
Publikováno v:
European journal of clinical pharmacology. 53(3-4)
The various good clinical practice (GCP) guidelines do not define the volunteering subject as an active party. The present survey addresses the volunteer's perception of study-related inconvenience and risk and its impact on their decision to enroll.
Publikováno v:
Arzneimittel-Forschung. 45(3)
A questionnaire was completed by members of the Association for Applied Human Pharmacology (AGAH) in Germany with the aim of assessing the present situation regarding management of adverse events (AEs). A recommendation for documentation and evaluati
Publikováno v:
European journal of clinical pharmacology. 46(4)
Sixteen healthy male subjects were investigated on four occasions when they received either placebo, 10 mg isosorbide dinitrate (ISDN), or 2.5 or 10 mg pirsidomine, a novel NO-donating drug. A constant-rate iv. infusion of a subsystemic dose (average