Zobrazeno 1 - 10
of 22
pro vyhledávání: '"M. Scribano"'
Autor:
Amber S Zhou, John B Tucker, Christina M Scribano, Andrew R Lynch, Caleb L Carlsen, Sophia T Pop-Vicas, Srishrika M Pattaswamy, Mark E Burkard, Beth A Weaver
Publikováno v:
PLoS Biology, Vol 21, Iss 10, p e3002339 (2023)
Microtubule-targeted agents are commonly used for cancer treatment, though many patients do not benefit. Microtubule-targeted drugs were assumed to elicit anticancer activity via mitotic arrest because they cause cell death following mitotic arrest i
Externí odkaz:
https://doaj.org/article/45f914589aa54be58c9b45687e9358a8
Autor:
Jun Wan, Samuel Block, Christina M. Scribano, Rebecca Thiry, Karla Esbona, Anjon Audhya, Beth A. Weaver
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
Mad1 is well characterised for its function in mitosis. Here, the authors describe an interphase role for Mad1 in tumour promotion in which it destabilises p53 by localizing to PML nuclear bodies and displacing MDM2 from the PML-MDM2 complex.
Externí odkaz:
https://doaj.org/article/2325e2e3c5334028a09c465010f83a6c
Autor:
Mark E. Burkard, Ning Jin, David J. Beebe, Beth A. Weaver, Lee G. Wilke, Ruth M. O'Regan, Amye J. Tevaarwerk, Kari B. Wisinski, Mouhita Humayun, Rachel E. Yan, Christina M. Scribano, John B. Tucker, Roshan X. Norman, Robert F. Lera, Stephanie M. McGregor, Baraa K. Manasrah, Yang Hu
Multinucleated H2B-RFP Tub-GFP MDA-MB-231 Multipolar Division
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10cde5cfaa91872e322c4a8409bc24b3
https://doi.org/10.1158/1535-7163.22522734.v1
https://doi.org/10.1158/1535-7163.22522734.v1
Autor:
Mark E. Burkard, Ning Jin, David J. Beebe, Beth A. Weaver, Lee G. Wilke, Ruth M. O'Regan, Amye J. Tevaarwerk, Kari B. Wisinski, Mouhita Humayun, Rachel E. Yan, Christina M. Scribano, John B. Tucker, Roshan X. Norman, Robert F. Lera, Stephanie M. McGregor, Baraa K. Manasrah, Yang Hu
Mononucleated H2B-RFP Tub-GFP MDA-MB-231 Bipolar Division
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4cb7ae04f6851d34fc80c9ea3ad040bc
https://doi.org/10.1158/1535-7163.22522740.v1
https://doi.org/10.1158/1535-7163.22522740.v1
Akademický článek
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Autor:
Amber Lasek, Jun Wan, Kayla Correia-Staudt, Tim S. Bugni, Kari B. Wisinski, Amber S. Zhou, Stephanie M. McGregor, Amy M. Fowler, Mark E. Burkard, Jonathan Fitzgerald, John B. Tucker, Karla Esbona, Lauren M. Zasadil, Christina M. Scribano, Amye J. Tevaarwerk, Ryan Molini, Beth A. Weaver, Ruth O'Regan, Angela M. Lager, Jennifer Laffin, Rick Chappell
Publikováno v:
Sci Transl Med
Paclitaxel (Taxol) is a cornerstone of cancer treatment. However, its mechanism of cytotoxicity is incompletely understood and not all patients benefit from treatment. We show that patients with breast cancer did not accumulate sufficient intratumora
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c001273086d6d430d83a6c11b9ba2676
https://doi.org/10.1126/scitranslmed.abd4811
https://doi.org/10.1126/scitranslmed.abd4811
Autor:
A. Aratari, M. Scribano, D. Pugliese, V. Baccolini, F. De Biasio, S. Verna, C. Morretta, S. Festa, A. Armuzzi, C. Papi
Publikováno v:
Digestive and Liver Disease. 54:S129-S130
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e51be242f2af739a97298143e0324901
https://doi.org/10.1016/s1590-8658(22)00407-8
https://doi.org/10.1016/s1590-8658(22)00407-8
Autor:
Christina M. Scribano, Anjon Audhya, Karla Esbona, Rebecca Thiry, Samuel Block, Jun Wan, Beth A. Weaver
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
Nature Communications
Nature Communications
Mitotic arrest deficient 1 (Mad1) plays a well-characterized role in the mitotic checkpoint. However, interphase roles of Mad1 that do not impact mitotic checkpoint function remain largely uncharacterized. Here we show that upregulation of Mad1, whic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7cedc2fd16532cecb56904475b1b0817
http://link.springer.com/article/10.1038/s41467-019-09471-9
http://link.springer.com/article/10.1038/s41467-019-09471-9
Autor:
Christina M. Scribano, Yang Hu, Baraa K. Manasrah, Mouhita Humayun, Roshan X. Norman, Lee G. Wilke, Stephanie M. McGregor, John B. Tucker, Rachel E. Yan, Beth A. Weaver, Ruth O'Regan, Amye J. Tevaarwerk, Ning Jin, Mark E. Burkard, David J. Beebe, Kari B. Wisinski, Robert F. Lera
Publikováno v:
Mol Cancer Ther
Taxanes remain one of the most effective medical treatments for breast cancer. Clinical trials have coupled taxanes with immune checkpoint inhibitors in patients with triple-negative breast cancer (TNBC) with promising results. However, the mechanism
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb9aad8871e07fab4b6876c1cc4e76cc
https://pubmed.ncbi.nlm.nih.gov/34583980
https://pubmed.ncbi.nlm.nih.gov/34583980
Akademický článek
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