Zobrazeno 1 - 10
of 1 564
pro vyhledávání: '"M. Schewe"'
Publikováno v:
Journal of Sensors and Sensor Systems, Vol 13, Pp 167-177 (2024)
A method is presented by which very small, slow, anharmonic signals can be extracted from measurement data overlaid with noise that is orders of magnitude larger than the signal of interest. To this end, a multi-step filtering process is applied to a
Externí odkaz:
https://doaj.org/article/6b5573f15832472abb4deaf0a731f21c
Autor:
Denis M. Schewe, Fotini Vogiatzi, Ira A. Münnich, Tobias Zeller, Roland Windisch, Christian Wichmann, Kristina Müller, Hilal Bhat, Elisa Felix, Dimitrios Mougiakakos, Heiko Bruns, Lennart Lenk, Thomas Valerius, Andreas Humpe, Matthias Peipp, Christian Kellner
Publikováno v:
HemaSphere, Vol 8, Iss 2, Pp n/a-n/a (2024)
Abstract CD19‐directed immunotherapy has become a cornerstone in the therapy of B‐cell precursor acute lymphoblastic leukemia (BCP‐ALL). CD19‐directed cellular and antibody‐based therapeutics have entered therapy of primary and relapsed dis
Externí odkaz:
https://doaj.org/article/9fd66e3abc514ac88a3fe38bc7edfa67
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-17 (2023)
Abstract Digitization of phase-modulated carrier signals with a commercially available analog-to-digital converter (ADC) is a common task in many communication and sensor applications. ADCs deliver phase-modulated digital carrier signals, which are n
Externí odkaz:
https://doaj.org/article/b7c09fa1443b48459d22260857d04e48
Autor:
Tobias Zeller, Ira A. Münnich, Roland Windisch, Patricia Hilger, Denis M. Schewe, Andreas Humpe, Christian Kellner
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Immune checkpoint blockade is a compelling approach in tumor immunotherapy. Blocking inhibitory pathways in T cells has demonstrated clinical efficacy in different types of cancer and may hold potential to also stimulate innate immune responses. A no
Externí odkaz:
https://doaj.org/article/e96b6e1f2fce44059fc705de5f9c4c60
Autor:
Lea Spory, Johannes Zimmermann, Michaela Vossen-Gajcy, Thomas Beder, Lorenz Bastian, Ameera Alsadeq, Dorothee Winterberg, Fotini Vogiatzi, Tim Wirbelauer, Hilal Bhat, Arndt Borkhardt, Sanil Bhatia, Martin Schrappe, Gunnar Cario, Denis M. Schewe, Lennart Lenk
Publikováno v:
HemaSphere, Vol 7, Iss 9, p e945 (2023)
Externí odkaz:
https://doaj.org/article/4121c3b59dfa474f93d735267a543fa8
Autor:
Regina Jitschin, Simon Völkl, Andreas Mackensen, Dimitrios Mougiakakos, Andreas Gießl, Heiko Bruns, Martin Böttcher, Rebecca Baur, Andrej Stoll, Thomas Fischer, Franziska Karl, Romy Böttcher-Loschinski, Cindy Flamann, Ursula Schlötzer-Schrehardt, Denis M Schewe
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss 3 (2023)
Allogeneic hematopoietic stem cell transplantation (allo-HSCT) represents the only curative treatment option for a number of hemato-oncological disorders. In fact, allo-HSCT is considered as one of the most successful immunotherapies as its clinical
Externí odkaz:
https://doaj.org/article/03f44df1f3a242ae85281eb8bc2b8891
Autor:
Michaela Kuhlen, Marina Kunstreich, Lienhard Lessel, Stefan A. Wudy, Paul-Martin Holterhus, Christian Vokuhl, Eva Juettner, Christoph Roecken, Guido Seitz, Christoph Slavetinsky, Jörg Fuchs, Denis M. Schewe, Rainer Claus, Pascal D. Johann, Michael C. Frühwald, Peter Vorwerk, Antje Redlich
Publikováno v:
EJC Paediatric Oncology, Vol 1, Iss , Pp 100015- (2023)
Background: Paediatric adrenocortical carcinomas (ACC) are highly aggressive malignancies with a dismal prognosis in advanced and metastatic diseases. Little is known about outcome of patients with refractory and relapsed (r/r) disease. Procedure: Na
Externí odkaz:
https://doaj.org/article/87befb459f374e449313ef4fba15ab29
Autor:
Tobias Zeller, Sebastian Lutz, Ira A. Münnich, Roland Windisch, Patricia Hilger, Tobias Herold, Natyra Tahiri, Jan C. Banck, Oliver Weigert, Andreas Moosmann, Michael von Bergwelt-Baildon, Cindy Flamann, Heiko Bruns, Christian Wichmann, Niklas Baumann, Thomas Valerius, Denis M. Schewe, Matthias Peipp, Thies Rösner, Andreas Humpe, Christian Kellner
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Antibody-dependent cellular phagocytosis (ADCP) by macrophages, an important effector function of tumor targeting antibodies, is hampered by ‘Don´t Eat Me!’ signals such as CD47 expressed by cancer cells. Yet, human leukocyte antigen (HLA) class
Externí odkaz:
https://doaj.org/article/741297763a5b405c9c2232db5b220176
Autor:
Michela Carlet, Kerstin Völse, Jenny Vergalli, Martin Becker, Tobias Herold, Anja Arner, Daniela Senft, Vindi Jurinovic, Wen-Hsin Liu, Yuqiao Gao, Veronika Dill, Boris Fehse, Claudia D. Baldus, Lorenz Bastian, Lennart Lenk, Denis M. Schewe, Johannes W. Bagnoli, Binje Vick, Jan Philipp Schmid, Alexander Wilhelm, Rolf Marschalek, Philipp J. Jost, Cornelius Miething, Kristoffer Riecken, Marc Schmidt-Supprian, Vera Binder, Irmela Jeremias
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-11 (2021)
Preclinical molecular models are useful that mimic a patient´s response to targeted therapy. Here, the authors establish an in vivo inducible RNAi-mediated gene silencing system in patient-derived xenograft models of acute leukemia to identify indiv
Externí odkaz:
https://doaj.org/article/6e797a213a574904a9cff02ded829844
Autor:
Niklas Baumann, Christian Arndt, Judith Petersen, Marta Lustig, Thies Rösner, Katja Klausz, Christian Kellner, Miriam Bultmann, Lorenz Bastian, Fotini Vogiatzi, Jeanette H. W. Leusen, Renate Burger, Denis M. Schewe, Matthias Peipp, Thomas Valerius
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Antibody-based immunotherapy is increasingly employed to treat acute lymphoblastic leukemia (ALL) patients. Many T-ALL cells express CD38 on their surface, which can be targeted by the CD38 antibody daratumumab (DARA), approved for the treatment of m
Externí odkaz:
https://doaj.org/article/aae84b3dbc6245b599a09797f9b180bc