Zobrazeno 1 - 10
of 47
pro vyhledávání: '"M. Sallas"'
Autor:
Guillaume Baneyx, William M. Sallas, Hequn Yin, Neva Coello, Jerry Nedelman, Penny Zhu, Francois Pierre Combes
Publikováno v:
Journal of Pharmacokinetics and Pharmacodynamics. 45:707-719
Everolimus is approved in Europe and in the USA for the adjunctive treatment of patients aged 2 years and older whose refractory partial-onset seizures, with or without secondary generalization, are associated with tuberous sclerosis complex. The obj
Autor:
Vassilios Aslanis, Xiaobin Li, Jianping Zhang, Taoufik Ouatas, William M. Sallas, Mary B. Wire
Publikováno v:
Clinical pharmacology and therapeutics. 104(6)
Our objective was to support initial eltrombopag doses and dose titration based on modeling and simulation of plasma exposure and platelet count response in pediatric patients aged 1-17 years with previously treated chronic immune thrombocytopenia en
Publikováno v:
Sarajevo Journal of Mathematics. 9:303-315
Publikováno v:
Social Marketing Quarterly. 16:2-17
Programa de Educación Sobre la Obesidad (PESO) was a targeted intervention which intended to raise awareness about the obesity epidemic, reduce the proportion of overweight and obese adults, and promote the consumption of fruits and vegetables withi
Autor:
Jeffrey L. Blumer, Adib F. Rodriguez, Guenther Kaiser, Pablo J. Sánchez, Kamal Hamed, William M. Sallas
Publikováno v:
Antimicrobial Agents and Chemotherapy. 54:2032-2041
A multicenter, open-label study evaluated the single-dose pharmacokinetics and safety of a pediatric oral famciclovir (prodrug of penciclovir) formulation in infants aged 1 to 12 months with suspicion or evidence of herpes simplex virus infection. In
Autor:
Xiao-Jian Zhou, Colm Farrell, June Ke, William M. Sallas, Douglas L. Mayers, Helen S. Pentikis
Publikováno v:
The Journal of Clinical Pharmacology. 49:725-734
Telbivudine is a new nucleoside analog indicated for the treatment of chronic hepatitis B infection. A population pharmacokinetic model was developed based on data pooled from 16 early phase studies in 363 healthy participants and patients. Telbivudi
Autor:
Gangadhar Sunkara, William M. Sallas, Venkateswar Jarugula, Steven E. Kern, Bahru Habtemariam, Goonaseelan Pillai
Publikováno v:
Drug Metabolism and Pharmacokinetics. 24:145-152
The objective of this work was to develop a population pharmacokinetic model to assess the influence of subject covariates on the pharmacokinetics of valsartan in children. Data were collected from a single dose study in 26 hypertensive children ages
Autor:
James E. Foley, Anne Horowitz, Monica Ligueros-Saylan, Yan-Ling He, Catherine Watson, William M. Sallas
Publikováno v:
The Journal of Clinical Pharmacology. 47:127-131
Publikováno v:
Clinical Pharmacology & Therapeutics. 74:138-149
Objective Our objective was to evaluate the drug-drug interactions of oxcarbazepine with coadministered antiepileptic drugs in children. Methods In a clinical trial, pediatric patients receiving an oxcarbazepine dose titrated to 30 to 46 mg · kg−1
Publikováno v:
Journal of Pharmacokinetics and Biopharmaceutics. 23:495-514
A nonlinear mixed-effects model simultaneously modeled two pharmacokinetic (PK) variables in patients administered cyclosporine twice daily: (i) concentration of drug in blood at the end of the 12-hr dosing interval (C12) and (ii) area under the conc