Zobrazeno 1 - 10
of 59
pro vyhledávání: '"M. Salditt-Georgieff"'
Publikováno v:
The EMBO Journal. 15:6262-6268
After interferon-gamma (IFN-gamma) treatment of cells the appearance of tyrosine phosphorylated Stat1 in the nucleus was maximal within 20-30 min, remained for 2-2.5 h and activated molecules disappeared by 4 h. In the absence of continued signaling
Publikováno v:
Proceedings of the National Academy of Sciences. 92:3829-3833
Interferon alpha induction of transcription operates through interferon-stimulated-gene factor 3 (ISGF), a transcription factor two components of which are members of the newly characterized Stat family of transcription factors. Interferon alpha indu
Publikováno v:
The EMBO journal. 15(22)
After interferon-gamma (IFN-gamma) treatment of cells the appearance of tyrosine phosphorylated Stat1 in the nucleus was maximal within 20-30 min, remained for 2-2.5 h and activated molecules disappeared by 4 h. In the absence of continued signaling
Publikováno v:
The Journal of Cell Biology
A kinetic analysis of the appearance of [3H]uridine label in RNA sequences that neighbor poly(A), as well as the incorporation of [3H]adenosine label into both the RNA chain and the poly(A) of poly(A)-containing molecules, shows that poly(A) is added
Autor:
M. Morgan, Warren Jelinek, Y. Furuichi, M. Salditt-Georgieff, Aaron J. Shatkin, James E. Darnell
Publikováno v:
Cell. 7:227-237
The majority of the mRNA molecules in HeLa cells contain 1-2 residue(s) of m6Ap and one blocked, methylated 5' terminal "cap" structure. The hnRNA, which is longer than mRNA, contains both m6Ap and caps but 4-6 times as many m6Ap residues per chain.
Autor:
James E. Darnell, M. Salditt-Georgieff
Publikováno v:
Molecular and Cellular Biology. 2:701-707
Nuclear RNA from Chinese hamster ovary cells was effectively separated into polyadenylic acid [poly(A)]-containing [poly (A)+] and non-poly(A)-containing [poly(A)−] fractions so that ∼90% of the poly(A) was present in the (A)+fraction. Only 25% o
Autor:
Michael Sheffery, M. Salditt-Georgieff, Paul A. Marks, Richard A. Rifkind, James E. Darnell, K.S. Krauter
Publikováno v:
Journal of Molecular Biology. 172:437-450
The transcription of the β-globin genes in mouse erythroleukemia cells has beenexamined by hybridizing labeled RNA obtained from isolated nuclei after chain elongation in the presence of [α- 32 P]UTP. There is induction of at least 30-fold of β ma
Publikováno v:
The Journal of Cell Biology
Normal adult rat hepatocytes plated on rat tail collagen-coated dishes and fed a chemically defined medium supplemented with epidermal growth factor and dimethylsulfoxide (DMSO) were examined over a 40-d culture period for (a) the amount of albumin s
Publikováno v:
Molecular and Cellular Biology. 1:179-187
The rate of synthesis in Chinese hamster cells of 5' cap structures, m7 GpppNmp, in large (greater than 700 bases) heterogeneous nuclear ribonucleic acid (RNA) molecules is two to three times faster than the synthesis of 3'-terminal polyadenylic acid
Autor:
Warren Jelinek, M. Salditt-Georgieff, James E. Darnell, Maureen A. Morgan, Yasuhiro Furuichi, A J Shatkin
Publikováno v:
Proceedings of the National Academy of Sciences. 72:1904-1908
Poly(A)-containing HeLa cell mRNA prepared from cells labeled with [methyl-(3)H]methionine or [(32)P]phosphate was found to contain a variety of methylated, blocked 5'-terminal structures of two general types: m(7)GpppN(7)-Np and m(7)GpppN(m)-N(m)-Np