Zobrazeno 1 - 10
of 18
pro vyhledávání: '"M. Saeed Qureshi"'
Autor:
M. Saeed Qureshi, Jawaher Alsughayyir, Manu Chhabra, Jason M. Ali, Martin J. Goddard, Chris Devine, Thomas M. Conlon, Michelle A. Linterman, Reza Motallebzadeh, Gavin J. Pettigrew
Publikováno v:
Data in Brief, Vol 22, Iss , Pp 647-657 (2019)
This data is related to the research article entitled “Germinal center humoral autoimmunity independently mediates progression of allograft vasculopathy” (Harper et al., 2016) [2]. The data presented here focuses on the humoral autoimmune respons
Externí odkaz:
https://doaj.org/article/df626946d39f4cb19d93b1dff87001a2
Autor:
Manu Chhabra, Jawaher Alsughayyir, M. Saeed Qureshi, Mekhola Mallik, Jason M. Ali, Ivonne Gamper, Ellen L. Moseley, Sarah Peacock, Vasilis Kosmoliaptsis, Martin J. Goddard, Michelle A. Linterman, Reza Motallebzadeh, Gavin J. Pettigrew
Publikováno v:
Frontiers in Immunology, Vol 9 (2019)
Different profiles of alloantibody responses are observed in the clinic, with those that persist, often despite targeted treatment, associated with poorer long-term transplant outcomes. Although such responses would suggest an underlying germinal cen
Externí odkaz:
https://doaj.org/article/0bc102d620cb4014b3986867ba41750e
Autor:
Jawaher Alsughayyir, Manu Chhabra, M. Saeed Qureshi, Mekhola Mallik, Jason M. Ali, Ivonne Gamper, Ellen L. Moseley, Sarah Peacock, Vasilis Kosmoliaptsis, Martin J. Goddard, Michelle A. Linterman, Reza Motallebzadeh, Gavin J. Pettigrew
Publikováno v:
Frontiers in Immunology, Vol 9 (2019)
Humoral alloimmunity is now recognized as a major determinant of transplant outcome. MHC glycoprotein is considered a typical T-dependent antigen, but the nature of the T cell alloresponse that underpins alloantibody generation remains poorly underst
Externí odkaz:
https://doaj.org/article/2ead543d0c1748e9bcdf4d6a176dd7b3
Augmentation of Recipient Adaptive Alloimmunity by Donor Passenger Lymphocytes within the Transplant
Autor:
Ines G. Harper, Jason M. Ali, Simon J.F. Harper, Elizabeth Wlodek, Jawaher Alsughayyir, Margaret C. Negus, M. Saeed Qureshi, Reza Motalleb-Zadeh, Kourosh Saeb-Parsy, Eleanor M. Bolton, J. Andrew Bradley, Menna R. Clatworthy, Thomas M. Conlon, Gavin J. Pettigrew
Publikováno v:
Cell Reports, Vol 15, Iss 6, Pp 1214-1227 (2016)
Chronic rejection of solid organ allografts remains the major cause of transplant failure. Donor-derived tissue-resident lymphocytes are transferred to the recipient during transplantation, but their impact on alloimmunity is unknown. Using mouse car
Externí odkaz:
https://doaj.org/article/07a9ed976d0c42a78866dd7854f9ab85
Autor:
Jason M. Ali, Margaret C. Negus, Thomas M. Conlon, Ines G. Harper, M. Saeed Qureshi, Reza Motallebzadeh, Richard Willis, Kourosh Saeb-Parsy, Eleanor M. Bolton, J. Andrew Bradley, Gavin J. Pettigrew
Publikováno v:
Cell Reports, Vol 14, Iss 5, Pp 1232-1245 (2016)
Summary: MHC alloantigen is recognized by two pathways: “directly,” intact on donor cells, or “indirectly,” as self-restricted allopeptide. The duration of each pathway, and its relative contribution to allograft vasculopathy, remain unclear.
Externí odkaz:
https://doaj.org/article/4d21d09f7ab64d809b676569f934b23c
Autor:
Reza Motallebzadeh, Manu Chhabra, M. Saeed Qureshi, Martin Goddard, Gavin J. Pettigrew, Christopher A. Devine, Jawaher Alsughayyir, Thomas M. Conlon, Michelle A. Linterman, Jason M. Ali
Publikováno v:
Data in Brief
Data in Brief, Vol 22, Iss, Pp 647-657 (2019)
Data in Brief, Vol 22, Iss, Pp 647-657 (2019)
This data is related to the research article entitled “Germinal center humoral autoimmunity independently mediates progression of allograft vasculopathy” (Harper et al., 2016) [2]. The data presented here focuses on the humoral autoimmune respons
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bbdba526de64d64345aa462cf4e53c4f
http://europepmc.org/articles/PMC6327748
http://europepmc.org/articles/PMC6327748
Autor:
Thomas M. Conlon, Manu Chhabra, Michelle A. Linterman, Jason M. Ali, Reza Motallebzadeh, Gavin J. Pettigrew, Martin Goddard, Jawaher Alsughayyir, M. Saeed Qureshi, Christopher A. Devine
The development of humoral autoimmunity following organ transplantation is increasingly recognised, but of uncertain significance. We examine whether autoimmunity contributes independently to allograft rejection. In a MHC class II-mismatched murine m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7a362e17a6915ac48d04157d444ce48
Autor:
Jawaher, Alsughayyir, Manu, Chhabra, M Saeed, Qureshi, Mekhola, Mallik, Jason M, Ali, Ivonne, Gamper, Ellen L, Moseley, Sarah, Peacock, Vasilis, Kosmoliaptsis, Martin J, Goddard, Michelle A, Linterman, Reza, Motallebzadeh, Gavin J, Pettigrew
Publikováno v:
Frontiers in Immunology
Humoral alloimmunity is now recognized as a major determinant of transplant outcome. MHC glycoprotein is considered a typical T-dependent antigen, but the nature of the T cell alloresponse that underpins alloantibody generation remains poorly underst
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::1a45c396e1925f2e23522704f5ae4c62
https://pubmed.ncbi.nlm.nih.gov/30740108
https://pubmed.ncbi.nlm.nih.gov/30740108
Autor:
Simon J.F. Harper, M. Saeed Qureshi, Marg C. Negus, Elizabeth Wlodek, J. Andrew Bradley, Manu Chhabra, Mekhola Mallik, Gavin J. Pettigrew, I. Harper, Eleanor M. Bolton, Jason M. Ali
Publikováno v:
Proceedings of the National Academy of Sciences. 112:12788-12793
Adaptive CD8 T-cell immunity is the principal arm of the cellular alloimmune response, but its development requires help. This can be provided by CD4 T cells that recognize alloantigen "indirectly," as self-restricted allopeptide, but this process re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb534132f0979c05e247fdf4a5eaaac3
https://doi.org/10.1073/pnas.1513533112
https://doi.org/10.1073/pnas.1513533112
Autor:
Reza Motallebzadeh, Sylvia Rehakova, Thomas M. Conlon, M. Saeed Qureshi, Chris J. Callaghan, Eleanor M. Bolton, Gavin J. Pettigrew, J. Andrew Bradley, Jennifer L. Cole, M. Negus, Kourosh Saeb-Parsy
Publikováno v:
The Journal of Immunology. 188:2643-2652
The durable alloantibody responses that develop in organ transplant patients indicate long-lived plasma cell output from T-dependent germinal centers (GCs), but which of the two pathways of CD4 T cell allorecognition is responsible for generating all
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b04ab99857c88352c441e3f417bac1f
https://doi.org/10.4049/jimmunol.1102830
https://doi.org/10.4049/jimmunol.1102830