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Autor:
Christina Janko, Maxim D. Lootsik, Tetyana Dumych, Christoph Alexiou, Andriy Mokhir, Leopold Sellner, Rostyslav Bilyy, Miroslav Sisa, Martin Herrmann, Evgenia Bila, Steffen Daum, M. S. Viktor Reshetnikov
Publikováno v:
Angewandte Chemie. 129:15751-15755
Cancer cells produce elevated levels of reactive oxygen species, which has been used to design cancer specific prodrugs. Their activation relies on at least a bimolecular process, in which a prodrug reacts with ROS. However, at low micromolar concent