Zobrazeno 1 - 10
of 46
pro vyhledávání: '"M. S. Nazarenko"'
Publikováno v:
Вавиловский журнал генетики и селекции, Vol 27, Iss 1, Pp 72-82 (2023)
In this study we compared methylation levels of 27,578 CpG sites between paired samples of the tumor and surrounding liver tissues with various degrees of damage (fibrosis, cirrhosis) in HCV-induced hepatocellular carcinoma (HCC) patients, as well as
Externí odkaz:
https://doaj.org/article/7473d89c21834f4982acd10afb732a8e
Publikováno v:
Российский кардиологический журнал, Vol 28, Iss 10 (2023)
Clonal hematopoiesis is a common age-dependent state accompanied by the expansion of mutant hematopoietic stem cells as a result of somatic mutations and is associated with a high risk of hematopoietic neoplasms and cardiovascular diseases. Clonal he
Externí odkaz:
https://doaj.org/article/2503d6e666964de4bc8a2b2f13ab612c
Autor:
N. P. Babushkina, M. A. Nikitina, E. Yu. Bragina, V. M. Alifirova, A. E. Postrigan, Ye. A. Deviatkina, D. E. Gomboeva, M. S. Nazarenko
Publikováno v:
Acta Biomedica Scientifica, Vol 7, Iss 6, Pp 12-21 (2022)
Background. Approximately 5–10 % of cases of Parkinson’s disease (PD) are monogenic, in other cases the pathology has a multifactorial etiology. One of recognized pathogenetic pathways of PD is mitochondrial dysfunction, in particular the accumul
Externí odkaz:
https://doaj.org/article/8c355cea200f4e5ab8aeefc8ca75df8c
Autor:
A. N. Kucher, N. R. Valiakhmetov, R. R. Salakhov, M. V. Golubenko, E. N. Pavlyukova, M. S. Nazarenko
Publikováno v:
Бюллетень сибирской медицины, Vol 21, Iss 3, Pp 205-216 (2022)
The review analyzes variability of clinical manifestations of p.Arg870His in the MYH7 gene, which is repeatedly registered in patients with hypertrophic cardiomyopathy (HCM). The analysis involves the data from scientific publications obtained as a s
Externí odkaz:
https://doaj.org/article/f5165208c4c04d87a554c0e473749b95
Publikováno v:
Вавиловский журнал генетики и селекции, Vol 25, Iss 8, Pp 855-863 (2022)
Linkage disequilibrium (LD) of single nucleotide polymorphisms (SNPs) of TLR4/AL160272.2 (rs1927914, rs1928298, rs7038716, rs7026297, rs7025144) was estimated in the Slavs of West Siberia. We further investigated an association of SNPs in TLR4/AL1602
Externí odkaz:
https://doaj.org/article/76a94568fdcc4582ab7ad5eaea580c46
Publikováno v:
Российский кардиологический журнал, Vol 27, Iss 12 (2023)
Aim. To analyze the comorbidity structure in patients with ascending thoracic aortic aneurysm (TAA) in the Siberian Federal District (SFD).Material and methods. The study included 163 patients (114 men (56,8±12,1 years) and 49 women (59,4±10,4 year
Externí odkaz:
https://doaj.org/article/1372f7ac574e48678fd4d99da24d42d1
Autor:
M. A. Nikitina, E. Yu. Bragina, M. S. Nazarenko, N. G. Zhukova, D. E. Gomboeva, K. F. Nurzhanova, N. V. Tsentr, V. M. Alifirova
Publikováno v:
Бюллетень сибирской медицины, Vol 19, Iss 4, Pp 235-240 (2021)
Huntington’s disease (HD) is an autosomal dominant progressive neurodegenerative disease. Its molecular cause is a cytosine-adenine-guanine (CAG) trinucleotide repeat dynamic expansion in the huntingtin (HTT) gene. Alleles with 36–39 CAG-repeats
Externí odkaz:
https://doaj.org/article/e893760408d04c12a8654aceb7524b6c
Autor:
A. A. Sleptsov, M. S. Nazarenko, A. V. Zaitseva, A. N. Kazantsev, N. N. Burkov, O. L. Barbarash, V. P. Puzyrev
Publikováno v:
Атеросклероз, Vol 15, Iss 4, Pp 46-51 (2019)
The goal of the study was to analyze copy number variation (CNV) in the GBP3 gene between white blood cells and atherosclerotic plaques of patients with carotid atherosclerosis. The material was both blood samples and atherosclerotic plaques obtained
Externí odkaz:
https://doaj.org/article/5cf8831ac95a48f588c169432372e8a8
Autor:
R. R. Salakhov, M. V. Golubenko, E. N. Pavlukova, A. N. Kucher, N. P. Babushkina, N. R. Valiahmetov, A. V. Markov, E. O. Belyaeva, A. F. Kanev, M. S. Nazarenko
Publikováno v:
Российский кардиологический журнал, Vol 26, Iss 10 (2021)
Aim. To investigate the application of the Oxford Nanopore Technologies’ third generation sequencing for the genetic testing of hypertrophic cardiomyopathy.Material and methods. The study involved 12 patients with hypertrophic cardiomyopathy aged 1
Externí odkaz:
https://doaj.org/article/e925f8e52fef4d8abf3af1c55cd6cb45
Autor:
Yu. A. Koroleva, A. V. Markov, I. A. Goncharova, A. A. Sleptsov, N. P. Babushkina, N. R. Valiakhmetov, D. V. Sharysh, A. A. Zarubin, M. S. Kuznetsov, B. N. Kozlov, M. S. Nazarenko
Publikováno v:
Российский кардиологический журнал, Vol 25, Iss 10 (2020)
Aim. Comparative analysis of the deoxyribonucleic acid (DNA) methylation level in the enhancer region of the CDKN2A/2B and CDKN2B-AS1 genes (9p21.3 locus) in vessels with/without atherosclerotic lesions, as well as in leukocytes of patients with clin
Externí odkaz:
https://doaj.org/article/dd2b098ea9ed4854a749ef7997ec1a6b