Zobrazeno 1 - 10
of 26
pro vyhledávání: '"M. S. Marber"'
Publikováno v:
Heart. 91:478-483
Objective: To investigate the influence of infarct zone viability on remodelling after late recanalisation of an occluded infarct related artery. Methods: A subgroup of 26 volunteers from TOAT (the open artery trial) underwent dobutamine stress cardi
Publikováno v:
Heart. 80:218-222
In patients with coronary artery disease, one of the most powerful determinants of prognosis is left ventricular function.1 2 Thus, if we assume that the prognostic benefit of revascularisation is mediated through an effect on left ventricular functi
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 266:H1534-H1540
Preconditioning has only been demonstrated in arterially perfused myocardium. Our aim was to develop a model of preconditioning in isolated, superfused, isometrically contracting rabbit right ventricular papillary muscle. This would eventually allow
Autor:
C L, Martyn-Simmons, R R, Ranawaka, P, Chowienczyk, M A, Crook, M S, Marber, C H, Smith, J N W N, Barker
Publikováno v:
The British journal of dermatology. 164(1)
There is well-documented evidence that patients with moderate and severe psoriasis have a significantly increased risk of cardiovascular disease (CVD). While this risk can, at least in part, be attributed to the high prevalence of traditional risk fa
Publikováno v:
International journal of clinical practice. 62(5)
To determine the relationship between insulin resistance (IR) and atheroma burden in Pakistanis.A prospective case-control study of 400 patients selected for the presence/absence of angiographic disease. Coronary atheroma burden was quantified and IR
Autor:
K M, Lawrence, A M N, Kabir, M, Bellahcene, S, Davidson, X B, Cao, J, McCormick, R A, Mesquita, C J, Carroll, A, Chanalaris, P A, Townsend, M, Hubank, A, Stephanou, R A, Knight, M S, Marber, D S, Latchman
Publikováno v:
FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 19(7)
Urocortin (Ucn) is an endogenous cardioprotective agent that protects against the damaging effects of ischemia and reperfusion injury in vitro and in vivo. We have found that the mechanism of action of Ucn involves both acute activation of specific t
Publikováno v:
Heart. 72:213-215
Publikováno v:
The Biochemical journal.
Delayed cytoprotection (preconditioning) occurs 24 h after sublethal simulated ischaemia and reperfusion (SI/R) in neonatal rat ventricular cardiomyocytes. SI/R was used to investigate the role of activation of mitogen-activated protein kinases (MAPK
Publikováno v:
British journal of clinical pharmacology. 50(2)
Publikováno v:
Cardiovascular drugs and therapy. 14(3)
Over the last 50 years, studies investigating the pathogenesis of left ventricular dysfunction have resulted in many potential therapeutic targets being identified and novel classes of drugs designed to treat this condition. Despite this, the long-te