Zobrazeno 1 - 10
of 51
pro vyhledávání: '"M. S. Legator"'
Autor:
Stephen K. Tyring, Lance M. Hallberg, M Y Heo, William W. Au, R el Zein, Gregg S. Wilkinson, M. S. Legator
Publikováno v:
Environmental Health Perspectives
The induction of a mutator phenotype has been hypothesized to cause the accumulation of multiple mutations in the development of cancer. Recent evidence suggests that the mutator phenotype is associated with DNA repair deficiencies. We have been usin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26ba3c9ad2a52e998fc51faf12cf2c8a
https://doi.org/10.1289/ehp.96104s3579
https://doi.org/10.1289/ehp.96104s3579
Publikováno v:
Clinical Chemistry. 41:1554-1559
We review several aspects of fluorescence in situ hybridization (FISH) technology that demonstrate its breadth and power in detecting and monitoring genetic abnormalities associated with cancers. The clinical utility of FISH in disease management is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6535fcd1f73069de59f73397369822d6
https://doi.org/10.1093/clinchem/41.11.1554
https://doi.org/10.1093/clinchem/41.11.1554
Autor:
M. S. Legator, William E. Bechtold, Jonathan B. Ward, Elbert B. Whorton, Marinel M. Ammenheuser
Publikováno v:
Environmental Health Perspectives
1,3-Butadiene is a major industrial chemical that has been shown to be a carcinogen at multiple sites in mice and rats at concentrations as low as 6.25 ppm. Occupational exposures have been reduced in response to these findings, but it may not be pos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0904776510f6e3390f189593781c1970
https://doi.org/10.1289/ehp.94102s979
https://doi.org/10.1289/ehp.94102s979
Autor:
M. S. Legator, William W. Au
Publikováno v:
Environmental Health Perspectives
Short-term in vitro genetic toxicity assays have not fulfilled their anticipated role in predicting the carcinogenicity of environmental agents reliably and economically. A reduction in emphasis from nonanimal systems to relevant animal assays and po
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6f2d15710428fb28a62cc9a9eb872e0
https://doi.org/10.1289/ehp.94102s9125
https://doi.org/10.1289/ehp.94102s9125
Autor:
M S, Legator
Publikováno v:
International journal of occupational and environmental health. 5(3)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::492e0b69f27e8395ac63dbcbc73d0b01
https://pubmed.ncbi.nlm.nih.gov/10441267
https://pubmed.ncbi.nlm.nih.gov/10441267
Response to the June 13, 1996, draft report of the Commission on Risk Assessment and Risk Management
Publikováno v:
Archives of environmental health. 52(5)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::85458eb63f0959670767b8d63ba41b00
https://pubmed.ncbi.nlm.nih.gov/9546763
https://pubmed.ncbi.nlm.nih.gov/9546763
Publikováno v:
Mutation research. 383(3)
Exposure to high concentrations of butadiene has been shown to cause cancer among exposed workers. We have conducted a biomarker study to elucidate whether current butadiene exposure conditions are hazardous to workers. Twenty-four workers exposed co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd7ee63eebdec76f390fe24758ae4af5
https://pubmed.ncbi.nlm.nih.gov/9164482
https://pubmed.ncbi.nlm.nih.gov/9164482
Autor:
L E, Morrison, M S, Legator
Publikováno v:
Cytometry. 27(4)
Ratio coding in fluorescence in situ hybridizations has the potential to identify more DNA and RNA targets simultaneously using fewer fluorescent labels than other multi-color techniques. Ratio coding uses hybridization probes containing different pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c64e8d6a9e4b9f13082c94e3c613d5d0
https://pubmed.ncbi.nlm.nih.gov/9098623
https://pubmed.ncbi.nlm.nih.gov/9098623
Publikováno v:
Clinical chemistry. 41(11)
We review several aspects of fluorescence in situ hybridization (FISH) technology that demonstrate its breadth and power in detecting and monitoring genetic abnormalities associated with cancers. The clinical utility of FISH in disease management is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ef7aae8719b07cd5636f13b6fa72415f
https://pubmed.ncbi.nlm.nih.gov/7586542
https://pubmed.ncbi.nlm.nih.gov/7586542
Publikováno v:
IARC scientific publications. (127)
Epidemiological evidence indicates that 1,3-butadiene is a human carcinogen; however, the epidemiological studies reflect past levels of exposures in the work place, which in all likelihood were higher than present-day levels. Studies of the metaboli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::6b58423f15d7361fda547b9d6c953f9d
https://pubmed.ncbi.nlm.nih.gov/8070871
https://pubmed.ncbi.nlm.nih.gov/8070871