Zobrazeno 1 - 10
of 15
pro vyhledávání: '"M. S. Hadley"'
Publikováno v:
ChemInform. 22
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5db72a5f71f99b6fa9c50084339e2c5c
https://doi.org/10.1002/chin.199104201
https://doi.org/10.1002/chin.199104201
Publikováno v:
ChemInform. 24
5-(2,2-Dimethyl-4a,6,7,7a-tetrahydro-2H,4H-[1,3]dioxino[5,4-b]pyrrol-4-yl)-2,2-dimethyl-4,5-dihydro-2H-1,3-dioxole-4-methanol, C 14 H 25 NO 5 , M r =287.4, trigonal, P3 2 21, a=11.831 (2), c=19.948 (7) A, V=2418.1 A 3 , Z=6, D x =1.18 g cm -3 , λ(Mo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0cf05f6b2df20f8e440a4499de11b3e3
https://doi.org/10.1002/chin.199316259
https://doi.org/10.1002/chin.199316259
Publikováno v:
ChemInform. 25
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::637196f5bd1b1a7403d29bbb9a3e8d0a
https://doi.org/10.1002/chin.199435265
https://doi.org/10.1002/chin.199435265
Autor:
S. H. J. Thompson, Robert A. Stockman, M. S. Hadley, Timothy Gallagher, David Lathbury, Peter Szeto
Publikováno v:
ChemInform. 28
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::74cdbfd3b8c91e664195504cee94ee4f
https://doi.org/10.1002/chin.199708121
https://doi.org/10.1002/chin.199708121
Publikováno v:
Acta Crystallographica Section C Crystal Structure Communications. 49:40-42
5-(2,2-Dimethyl-4a,6,7,7a-tetrahydro-2H,4H-[1,3]dioxino[5,4-b]pyrrol-4-yl)-2,2-dimethyl-4,5-dihydro-2H-1,3-dioxole-4-methanol, C 14 H 25 NO 5 , M r =287.4, trigonal, P3 2 21, a=11.831 (2), c=19.948 (7) A, V=2418.1 A 3 , Z=6, D x =1.18 g cm -3 , λ(Mo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::14df0ac6ef3e268649373d767a2007dd
https://doi.org/10.1107/s0108270192004517
https://doi.org/10.1107/s0108270192004517
Autor:
C, Reavill, S G, Taylor, M D, Wood, T, Ashmeade, N E, Austin, K Y, Avenell, I, Boyfield, C L, Branch, J, Cilia, M C, Coldwell, M S, Hadley, A J, Hunter, P, Jeffrey, F, Jewitt, C N, Johnson, D N, Jones, A D, Medhurst, D N, Middlemiss, D J, Nash, G J, Riley, C, Routledge, G, Stemp, K M, Thewlis, B, Trail, A K, Vong, J J, Hagan
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 294(3)
SB-277011-A (trans-N-[4-[2-(6-cyano-1,2,3, 4-tetrahydroisoquinolin-2-yl)ethyl]cyclohexyl]-4-quinolininecarboxamide), is a brain-penetrant, high-affinity, and selective dopamine D(3) receptor antagonist. Radioligand-binding experiments in Chinese hams
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::08a1378e0dba35339782ae1689d10d0e
https://pubmed.ncbi.nlm.nih.gov/10945872
https://pubmed.ncbi.nlm.nih.gov/10945872
Publikováno v:
J. Chem. Soc., Chem. Commun.. :831-833
Lithiation of the isomerically pure enol ethers (7) and (8) provides the organolithium derivatives (9) and (13) which were trapped with aldehydes and shown to function as synthetic equivalents of the pyrrolidin-3-one enoiate (3); aldehyde adducts (10
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d62adfdfa7c9897211f19038c75196ca
https://doi.org/10.1039/c39900000831
https://doi.org/10.1039/c39900000831
Autor:
M S, Hadley
Publikováno v:
Medicinal research reviews. 16(6)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0601be0142ddd765b2659bbc4a5d3506
https://pubmed.ncbi.nlm.nih.gov/8923442
https://pubmed.ncbi.nlm.nih.gov/8923442
Publikováno v:
ChemInform. 21
Lithiation of the isomerically pure enol ethers (7) and (8) provides the organolithium derivatives (9) and (13) which were trapped with aldehydes and shown to function as synthetic equivalents of the pyrrolidin-3-one enoiate (3); aldehyde adducts (10
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0f2079584524fe009a2e4edaf4d4460a
https://doi.org/10.1002/chin.199048138
https://doi.org/10.1002/chin.199048138
Publikováno v:
J. Chem. Soc., Chem. Commun.. :1047-1048
Double deprotonation of β-ketoester (6) gives dianion (7) which serves as a synthetic equivalent of the regiospecific ketone enolate (3), providing a synthetic entry to 2-substituted pyrrolidin-3-ones (9) and (10).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::73ae6ef265f8a47f5e83b0eeff2e1037
https://doi.org/10.1039/c39900001047
https://doi.org/10.1039/c39900001047