Zobrazeno 1 - 10
of 84
pro vyhledávání: '"M. S. Freedman"'
Autor:
Jennifer Graves, Adrian Pace, Maria Pia Sormani, Devon S. Conway, Bianca Weinstock-Guttman, Frederick E. Munschauer, Corey C. Ford, Vernon Rowe, Jana Lizrova Preiningerova, Shiv Saidha, Radek Ampapa, Jens Kuhle, Harold L. Moses, Claire S Riley, Tobias Derfuss, Lilyana Amezcua, Joshua Barton, Kottil Rammohan, Pierre Duquette, Thomas Leist, Alexander Rae-Grant, Evanthia Bernitsas, Myla D. Goldman, R. Talab, Jerry S. Wolinsky, Nina De Klippel, Guillermo Izquierdo Ayuso, Bridget Bagert, Virginia Devonshire, Mariko Kita, Hayrettin Tumani, Bhatia Perminder, Scott D. Newsome, Paul S. Giacomini, Frédéric Sedel, Jan Lycke, M. S. Freedman, Stewart Webb, Sanjay Yathiraj, Agata Klosek, Stephen Krieger, Edward Fox, Malgorzata Zajda, Eva Meluzinova, Valerie J Block, Lluís Ramió-Torrentà, John R. Corboy, Aaron E. Miller, Xavier Montalban, Mark A. Agius, Michelle L Apperson, Patricia K. Coyle, Giancarlo Comi, Jose Enrique Martinez Rodriguez, Daniela Rau, Derrick Robertson, Elias Hamp Birte, Douglas L. Arnold, Fred D. Lublin, Galina Vorobeychik, Benjamin Greenberg, Mathias Buttmann, Daniel Bandari, Ludivine Witkowski, Sharon G. Lynch, Victoria Fernandez Sanchez, Jonathan Calkwood, Maria Satori, Tania Kuempfel, Rana K. Zabad, J. Marc Girard, Bruce A.C. Cree, Ahmed T. Toosy, Don J. Mahad, Bruce A. Cohen, Jozef Koscielniak, Jonathan Carter, Daniel Selchen, Paul Friedemann, Sharon Stoll, Fryze Waldemar, Gerd Reifschneider, Mark S. Freedman, Gary Cutter, Franz Fazekas, Robert T. Naismith, Marta Vachova, Richard MacDonell, Mary Ann Picone, Gavin Giovannoni, Randall Trudell, Barbara Willekens, Orhan Aktas, Mark Marriott, Roger McKelvey, Bruce C.A. Cree, Christopher Severson, Rafael Arroyo Gonzalez, Kyle Smoot, Murat Terzi, Joanna Cooper, Lou Brundin, Hans-Peter Hartung, Piotr Sokolowski, Joe Guadagno, Stephen C. Reingold, Klaus Schmierer, Guy Laureys, Robert P. Lisak, Lawrence Samkoff, Carlo Pozzilli, Celia Oreja Guevara, Mitchel Freedman, Anthony T. Reder
Publikováno v:
The lancet neurology
Background: There is an unmet need to develop therapeutic interventions directed at the neurodegeneration that underlies progression in multiple sclerosis. High-dose, pharmaceutical-grade biotin (MD1003) might enhance neuronal and oligodendrocyte ene
Autor:
Christoph Pohl, Beyond, Bertram Müller-Myhsok, M. S. Freedman, Dorothea Buck, Stuart D. Cook, Till M.F. Andlauer, Frederik Barkhof, Frank Weber, Hans-Peter Hartung, Giancarlo Comi, Karl Köchert, Mark Mühlau, Ludwig Kappos, Bernhard Hemmer, Xavier Montalban, Benefit Study Groups, Douglas Jeffery, Massimo Filippi, Gilles Edan, Wilmar Igl, Eva-Maria Wicklein, Barry G. W. Arnason
Publikováno v:
MULTIPLE SCLEROSIS JOURNAL
Buck, D, Andlauer, T F, Igl, W, Wicklein, E-M, Mühlau, M, Weber, F, Köchert, K, Pohl, C, Arnason, B, Comi, G, Cook, S, Filippi, M, Hartung, H-P, Jeffery, D, Kappos, L, Barkhof, F, Edan, G, Freedman, M S, Montalbán, X, Müller-Myhsok, B, Hemmer, B & BEYOND and BENEFIT Study Groups 2019, ' Effect of HLA-DRB1 alleles and genetic variants on the development of neutralizing antibodies to interferon beta in the BEYOND and BENEFIT trials ', Multiple Sclerosis, vol. 25, no. 4, pp. 565-573 . https://doi.org/10.1177/1352458518763089
Multiple Sclerosis, 25(4), 565-573. SAGE Publications Ltd
Buck, D, Andlauer, T F, Igl, W, Wicklein, E-M, Mühlau, M, Weber, F, Köchert, K, Pohl, C, Arnason, B, Comi, G, Cook, S, Filippi, M, Hartung, H-P, Jeffery, D, Kappos, L, Barkhof, F, Edan, G, Freedman, M S, Montalbán, X, Müller-Myhsok, B, Hemmer, B & BEYOND and BENEFIT Study Groups 2019, ' Effect of HLA-DRB1 alleles and genetic variants on the development of neutralizing antibodies to interferon beta in the BEYOND and BENEFIT trials ', Multiple Sclerosis, vol. 25, no. 4, pp. 565-573 . https://doi.org/10.1177/1352458518763089
Multiple Sclerosis, 25(4), 565-573. SAGE Publications Ltd
Background: Treatment of multiple sclerosis (MS) with interferon β can lead to the development of antibodies directed against interferon β that interfere with treatment efficacy. Several observational studies have proposed different HLA alleles and
Autor:
Gustavo Suarez, Xavier Montalban, Gilles Edan, Frederik Barkhof, M. S. Freedman, Hans-Peter Hartung, Alberto Ascherio, Kassandra L. Munger, Christoph Pohl, Kathryn C. Fitzgerald, Rupert Sandbrink, Ludwig Kappos, Ernst Wilhelm Radue, David Miller
Publikováno v:
Neurology
Neurology, 2015, 85 (19), pp.1694--1701. ⟨10.1212/WNL.0000000000002099⟩
Neurology, American Academy of Neurology, 2015, 85 (19), pp.1694--1701. ⟨10.1212/WNL.0000000000002099⟩
Munger, K L, Fitzgerald, K C, Freedman, M S, Hartung, H P, Miller, D H, Montalban, X, Edan, G, Barkhof, F, Suarez, G, Radue, E W, Sandbrink, R, Kappos, L, Pohl, C & Ascherio, A 2015, ' No association of multiple sclerosis activity and progression with EBV or tobacco use in BENEFIT ', Neurology, vol. 85, no. 19, pp. 1694-1701 . https://doi.org/10.1212/WNL.0000000000002099
Neurology, 85(19), 1694-1701. Lippincott Williams and Wilkins
Neurology, 2015, 85 (19), pp.1694--1701. ⟨10.1212/WNL.0000000000002099⟩
Neurology, American Academy of Neurology, 2015, 85 (19), pp.1694--1701. ⟨10.1212/WNL.0000000000002099⟩
Munger, K L, Fitzgerald, K C, Freedman, M S, Hartung, H P, Miller, D H, Montalban, X, Edan, G, Barkhof, F, Suarez, G, Radue, E W, Sandbrink, R, Kappos, L, Pohl, C & Ascherio, A 2015, ' No association of multiple sclerosis activity and progression with EBV or tobacco use in BENEFIT ', Neurology, vol. 85, no. 19, pp. 1694-1701 . https://doi.org/10.1212/WNL.0000000000002099
Neurology, 85(19), 1694-1701. Lippincott Williams and Wilkins
International audience; Objective: To evaluate whether Epstein-Barr virus (EBV) immunoglobulin G (IgG) antibody levels or tobacco use were associated with conversion to multiple sclerosis (MS) or MS progression/activity in patients presenting with cl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a06f470f7b8436d8fc5d71d397cdedeb
https://univ-rennes.hal.science/hal-01239811
https://univ-rennes.hal.science/hal-01239811
Autor:
Nathalie Arbour, A. Buddiga, Josephine Nalbantoglu, Elizabeth Villalobos-Menuey, M. B. Sorensen, Amit Bar-Or, Scott S. Zamvil, M. K. Newell, M. Burnett, M. S. Freedman, Ellie McCrea, Richard P Tobin, Jack P. Antel, C. P. Harvey, A. Huckstep, J. H. Cabrera
Publikováno v:
Journal of Leukocyte Biology. 88:779-789
TLR stimulation results in polyclonal B cell activation, ectopic CLIP expression, release of T cell-derived TNFα, and reversal with high affinity peptide treatment. Infectious pathogens produce compounds called Toll ligands that activate TLRs on lym
Autor:
Marie-Emmanuelle Dilenge, Silvia Tenembaum, Mark A. Hancock, M. S. Freedman, L. Kopel, R. Fattahie, Dawn Gano, Brenda Banwell, Mario A. Moscarello, Mary Rensel, Alyson E. Fournier, O. Bykova, Donald Gagne, Jayne Ness, N.H. Moore-Odom, C.A. Stoian, Julia Kennedy, Alexey Boyko, M.R. Bardini, Anita Belman, E. A. Yeh, Martino Ruggieri, Matti Iivanainen, Bianca Weinstock-Guttman, Lauren B. Krupp, Emmanuelle Waubant, C. Lopez-Amaya, Amit Bar-Or, Kevin Farrell, Laura Lovato, Marcelo Kremenchutzky, J. Mah, Virender Bhan, Kevin C. O’Connor, Jin S. Hahn
Publikováno v:
Journal of Neuroimmunology. 223:92-99
Anti-myelin basic protein (MBP) antibodies in pediatric-onset MS and controls were characterized. Serum samples were obtained from 94 children with MS and 106 controls. Paired CSF and serum were obtained from 25 children with MS at time of their init
Autor:
Alan J. Thompson, Stephen C. Reingold, J. P. Steiner, Chris H. Polman, J. A. Cohen, Jerry S. Wolinsky, Ludwig Kappos, M. S. Freedman
Publikováno v:
Neurology, 73(7), 552-559. Lippincott Williams and Wilkins
Reingold, S C, Steiner, J P, Polman, C H, Cohen, J A, Freedman, M S, Kappos, L, Thompson, A J & Wolinsky, J S 2009, ' The challenge of follow-on biologics for treatment of multiple sclerosis ', Neurology, vol. 73, no. 7, pp. 552-559 . https://doi.org/10.1212/WNL.0b013e3181b2a6ce
Reingold, S C, Steiner, J P, Polman, C H, Cohen, J A, Freedman, M S, Kappos, L, Thompson, A J & Wolinsky, J S 2009, ' The challenge of follow-on biologics for treatment of multiple sclerosis ', Neurology, vol. 73, no. 7, pp. 552-559 . https://doi.org/10.1212/WNL.0b013e3181b2a6ce
Intellectual property protections for biologic medicinals for multiple sclerosis (MS) are beginning to expire, opening the possibility of development, regulatory approval, and marketing of so-called follow-on biologics, biosimilars, or subsequent ent
Autor:
L, Kappos, C H, Polman, M S, Freedman, G, Edan, H P, Hartung, D H, Miller, X, Montalban, F, Barkhof, L, Bauer, P, Jakobs, C, Pohl, R, Sandbrink
Publikováno v:
Neurology. 67:1242-1249
To assess efficacy, safety, and tolerability of every-other-day interferon beta-1b treatment in patients with a first clinical event suggestive of multiple sclerosis (MS) (clinically isolated syndrome).We conducted a multicenter, randomized, double-b
Autor:
Brenda Banwell, Lauren B. Krupp, Daniela Pohl, M. S. Freedman, B. Alexey, Anthony T. Reder, L. Schelensky, Mefkure Eraksoy, Silvia Tenembaum, I. Antonijevic
Publikováno v:
Neurology. 66:472-476
Background: Immunomodulatory therapies are widely used in adults with multiple sclerosis (MS) and safety and tolerability is well-established. Although at least 5% of all patients with MS experience the clinical onset of their disease prior to age 18
Autor:
M. S Freedman
Publikováno v:
Multiple Sclerosis. 10:S31-S35
Publikováno v:
Nuclear Instruments and Methods in Physics Research Section A: Accelerators, Spectrometers, Detectors and Associated Equipment. 396:181-197
The use of an ultracold neutron interferometer incorporating an electrostatic accelerator having a strong electric field gradient to accelerate neutrons by their possible electric moments is proposed as a method of measuring the neutron electric dipo