Zobrazeno 1 - 10
of 48
pro vyhledávání: '"M. S. Ernstoff"'
Autor:
I. Puzanov, A. Diab, K. Abdallah, C. O. Bingham, C. Brogdon, R. Dadu, L. Hamad, S. Kim, M. E. Lacouture, N. R. LeBoeuf, D. Lenihan, C. Onofrei, V. Shannon, R. Sharma, A. W. Silk, D. Skondra, M. E. Suarez-Almazor, Y. Wang, K. Wiley, H. L. Kaufman, M. S. Ernstoff, on behalf of the Society for Immunotherapy of Cancer Toxicity Management Working Group
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 5, Iss 1, Pp 1-28 (2017)
Abstract Cancer immunotherapy has transformed the treatment of cancer. However, increasing use of immune-based therapies, including the widely used class of agents known as immune checkpoint inhibitors, has exposed a discrete group of immune-related
Externí odkaz:
https://doaj.org/article/a958c2815f5e4989bd5513b2bad7e525
Publikováno v:
Journal of Clinical Oncology. 41:425-435
PURPOSE Interferon alfa-2b (IFN alpha-2b) exhibits antitumor activity in metastatic melanoma and on this basis has been evaluated as an adjuvant therapy following surgery for deep primary (T4) or regionally metastatic (N1) melanoma. METHODS A randomi
Autor:
Michael A. Postow, Peter A. Forsyth, Hussein Abdul-Hassan Tawbi, Igor Puzanov, Ahmad A. Tarhini, Jasmine I. Rizzo, Alain Algazi, F. Stephen Hodi, Omid Hamid, Anna C. Pavlick, Sekwon Jang, Ragini R. Kudchadkar, Christopher D. Lao, Karl D. Lewis, David A. Reardon, Nikhil I. Khushalani, Stergios J. Moschos, Kim Margolin, John A. Glaspy, Reena Thomas, Anne Sumbul, Michael B. Atkins, M. S. Ernstoff
Publikováno v:
Neuro-Oncology
Neuro Oncol
Neuro-oncology, vol 23, iss 11
Neuro Oncol
Neuro-oncology, vol 23, iss 11
Background In patients with melanoma and asymptomatic brain metastases (MBM), nivolumab plus ipilimumab provided an intracranial response rate of 55%. Here, we present the first report for patients who were symptomatic and/or required corticosteroids
Autor:
John A. Thompson, Jeffrey S. Weber, Leslie A. Fecher, Cristina A. Reichner, Yinghong Wang, Maria E. Suarez-Almazor, Michael B. Atkins, Carole Seigel, Milan J. Anadkat, Umang Swami, Laura Diane Porter, Sherry Adkins, Alexander I. Spira, Tanyanika Phillips, Monalisa Ghosh, Ishmael Jaiyesimi, M. S. Ernstoff, Jarushka Naidoo, Jeffrey M. Caterino, Jung-Min Song, Marianne Davies, Ian Chau, Aung Naing, Kelly J. Brassil, Loretta J. Nastoupil, Bryan J. Schneider, Jennifer S. Mammen, Christina Lacchetti, Bianca Santomasso, Pauline Funchain, Kathryn Bollin, Praveen Vikas
Publikováno v:
Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 39(35)
PURPOSE To increase awareness, outline strategies, and offer guidance on the recommended management of immune-related adverse events (irAEs) in patients treated with chimeric antigen receptor (CAR) T-cell therapy. METHODS A multidisciplinary panel of
Autor:
Michael B. Atkins, Kelly J. Brassil, Jeffrey S. Weber, Ishmael Jaiyesimi, Jarushka Naidoo, M. S. Ernstoff, Bryan J. Schneider, Jennifer S. Mammen, Cristina A. Reichner, Laura Diane Porter, Ian Chau, Yinghong Wang, John A. Thompson, Jung-Min Song, Monalisa Ghosh, Christina Lacchetti, Jeffrey M. Caterino, Tanyanika Phillips, Loretta J. Nastoupil, Carole Seigel, Praveen Vikas, Maria E. Suarez-Almazor, Leslie A. Fecher, Bianca Santomasso, Milan J. Anadkat, Pauline Funchain, Sherry Adkins, Aung Naing, Kathryn Bollin, Umang Swami, Marianne Davies, Alexander I. Spira
Publikováno v:
Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 39(36)
PURPOSE To increase awareness, outline strategies, and offer guidance on the recommended management of immune-related adverse events (irAEs) in patients treated with immune checkpoint inhibitor (ICPi) therapy. METHODS A multidisciplinary panel of med
Autor:
Margarita Askelson, Igor Puzanov, Ragini R. Kudchadkar, Alain Algazi, Michael A. Postow, Omid Hamid, Nikhil I. Khushalani, Anna C. Pavlick, Karl D. Lewis, Hussein Abdul-Hassan Tawbi, John A. Glaspy, Christopher D. Lao, Kim Margolin, F. Stephen Hodi, Stergios J. Moschos, Ahmad A. Tarhini, Caroline Chung, David A. Reardon, Piyush Durani, Peter A. Forsyth, Reena Thomas, Sekwon Jang, M. S. Ernstoff, Corey Ritchings, Michael B. Atkins
Publikováno v:
The Lancet. Oncology, vol 22, iss 12
Lancet Oncol
Lancet Oncol
Summary Background Combination nivolumab plus ipilimumab was efficacious in patients with asymptomatic melanoma brain metastases (MBM) in CheckMate 204, but showed low efficacy in patients with symptomatic MBM. Here, we provide final 3-year follow-up
Autor:
Jarushka Naidoo, Douglas B. Johnson, Frank B. Cortazar, Michelle Turner, Michele Nanni, Miguel-Angel Perales, Eric Hansen, M. S. Ernstoff, Jill Brufsky, Lamya Hamad, Bianca Santomasso, Dimitra Skondra, Igor Puzanov, Jeffrey A. Sosman, Laura C. Cappelli, Satish Shanbhag, Hamzah Abu-Sbeih, Gregory A. Masters, Mario E. Lacouture, Paolo A. Ascierto, David E. Gerber, Julie R. Brahmer, Rajeev Sharma
Publikováno v:
Journal for Immunotherapy of Cancer
Journal for ImmunoTherapy of Cancer, Vol 9, Iss 6 (2021)
Journal for ImmunoTherapy of Cancer, Vol 9, Iss 6 (2021)
Immune checkpoint inhibitors (ICIs) are the standard of care for the treatment of several cancers. While these immunotherapies have improved patient outcomes in many clinical settings, they bring accompanying risks of toxicity, specifically immune-re
Autor:
F.S. Hodi, Christopher D. Lao, Margarita Askelson, David A. Reardon, Omid Hamid, Kim Margolin, Anna C. Pavlick, M. S. Ernstoff, Reena Thomas, C-W. Lee, Nikhil I. Khushalani, Michael A. Postow, Michael B. Atkins, Alain Algazi, Caroline Chung, Karl D. Lewis, Tuba Bas, Peter A. Forsyth, Stergios J. Moschos, H.A. Tawbi
Publikováno v:
Annals of Oncology. 32:S871-S872
Autor:
Amanda Przespolewski, Matthew Gravina, Megan M. Herr, Eti Sinha, Nuria Mencia-Trinchant, Elizabeth A. Griffiths, LunBiao Yan, Abhay Singh, Duane C. Hassane, Monica L. Guzman, M. S. Ernstoff, Mahesh Swaminathan, Mark G. Faber, Rutaba Tajammal, Eunice S. Wang, Swapna Thota
Publikováno v:
Blood. 138:4295-4295
Background. DNA methylation is a key epigenetic process involved in development, aging, and cancer. Mutations in DNMT3A and TET2 in the hematopoietic stem cell compartment lead to increased self-renewal. In addition to mutations in ASXL1, collectivel
Autor:
M S, Ernstoff
Publikováno v:
Clinics in plastic surgery. 27(3)
Identification of early and thin cutaneous melanoma has a significant impact on overall survival. Through education efforts physicians, health care providers, and the public can identify risk categories that may benefit from screening. Early detectio