Zobrazeno 1 - 5
of 5
pro vyhledávání: '"M. S. Connors"'
Publikováno v:
Xenobiotica. 26:133-141
1. Cleavage of the glucopyranosyl moiety of the somatostatin analogue SDZ CO 611 results in the formation of the major metabolite, SDZ CO 610, in liver and kidney slices of rat, dog and man, as well as in liver S9 and cytosol of rat and man. 2. The r
Publikováno v:
Xenobiotica. 22:325-334
1. Pentachlorophenyl methyl sulphoxide and pentachlorophenyl methyl sulphone were found to be substrates for microsomal and cytosolic glutathione-S-transferase of rabbit, monkey, chicken and human liver, covalently immobilized on beaded sepharose. 2.
Publikováno v:
Cancer research. 56(11)
A major target tissue for carcinogenesis from the cooked-food carcinogen 2-amino-l-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) in rodents is the colon, yet the role of colon metabolism on the carcinogenicity of PhIP is not clearly understood. The mu
Autor:
W. A. Biggi, Volker Fischer, M. S. Connors, J.-P. Baldeck, A. E. M. Vickers, K. Brendel, Francis Heitz
Publikováno v:
European journal of drug metabolism and pharmacokinetics. 21(1)
Species differences in the biotransformation of the antiemetic tropisetron, a potent 5-hydroxytryptamine type 3 (5-HT3) receptor antagonist, were evident in liver slice incubates of human, rat and dog, and reflected the species differences observed i
Publikováno v:
Proceedings of the Western Pharmacology Society. 31