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Both viral E2 protein and the cellular factor PEBP2 regulate transcription via E2 consensus sites within the bovine papillomavirus type 4 long control region

Autor: M E Jackson, M S Campo

Publikováno v: Journal of Virology. 69:6038-6046

The bovine papillomavirus type 4 (BPV4) long control region (LCR) contains three consensus binding sites, E2(1), E2(2), and E2(3) (ACCN6GGT), for the viral E2 transcription factor and a fourth degenerate site, dE2 (ATCN6GGT), which lies 3 bp upstream

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6fd24dce3b67040ae110b2c2ca594c90
https://doi.org/10.1128/jvi.69.10.6038-6046.1995

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The enhancer in the long control region of human papillomavirus type 16 is up-regulated by PEF-1 and down-regulated by Oct-1

Autor: S Cuthill, G J Sibbet, M S Campo

Publikováno v: Journal of Virology. 69:4006-4011

The minimal enhancer in the long control region of human papillomavirus type 16 regulates cell type and constitutive expression from the promoter P97. This region contains at least four DNase I footprints (fp4e, fp5e, fp6e, and fp7e). We have shown t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ba311fb4332a1d843c405da8769cea4
https://doi.org/10.1128/jvi.69.7.4006-4011.1995

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The synergism between bovine papillomavims type 4 and quercetin is dependent on the timing of exposure

Autor: M. Cairney, M. S. Campo

Publikováno v: Carcinogenesis. 16:1997-2001

Exposure to the flavonoid quercetin and transfection with bovine papillomavirus type 4 (BPV-4) DNA lead to oncogenic transformation of primary bovine cells. Here we show that the synergism between quercetin and BPV-4 (or its E7 oncogene) is stronger

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df00e2ccb34c1872332bbcf5dc63ce7f
https://doi.org/10.1093/carcin/16.8.1997

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Vaccination Against Cutaneous and Mucosal Papillomavirus in Cattle

Autor: W F Jarrett, M S Campo

Publikováno v: Ciba Foundation Symposium 187-Vaccines Against Virally Induced Cancers

Viruses are responsible for approximately 15% of human cancer worldwide. Human papillomavirus and hepatitis B virus are the recognized agents of cervical and liver cancer, respectively, which together constitute 80% of all virally induced cancers. If

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::3d88d6037f468ef61198958d865f56bf
https://doi.org/10.1002/9780470514672.ch5

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Cell transformation by the E5/E8 protein of bovine papillomavirus type 4. p27(Kip1), Elevated through increased protein synthesis is sequestered by cyclin D1-CDK4 complexes

Autor: V, O'Brien, G J, Grindlay, M S, Campo

Publikováno v: The Journal of biological chemistry. 276(36)

The E5/E8 hydrophobic protein of BPV-4 is, at only 42 residues, the smallest transforming protein identified to date. Transformation of NIH-3T3 cells by E5/E8 correlates with up-regulation of both cyclin A-associated kinase activity and, unusually, p

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::980fa3f080d3769eb613009c26c94b73
https://pubmed.ncbi.nlm.nih.gov/11448948

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Generation of native bovine mAbs by phage display

Autor: B. W. O’Neil, P. M. O’Brien, R. Aitken, M. S. Campo

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America. 96(2)

Modeling of disease pathogenesis and immunity often is carried out in large animals that are natural targets for pathogens of human or economic relevance. Although murine mAbs are a valuable tool in identifying certain host/pathogen interactions, pro

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78bee92e102ba87abf28b4032c141da1
https://pubmed.ncbi.nlm.nih.gov/9892686

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PEF-1, an epithelial cell transcription factor which activates the long control region of human papillomavirus type 16, is glycosylated with N-acetylglucosamine

Autor: M S Campo, David Fergusson

Publikováno v: The Journal of general virology. 79

Infection by human papillomavirus type 16 (HPV-16) has been linked to cervical cancer. The transcription of viral genes in HPV-16 is partially controlled by a number of cellular transcription factors. We have previously identified a novel cellular tr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::770ef853402570eab3da70240117cbaf
https://pubmed.ncbi.nlm.nih.gov/9820151

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Variation of human papillomavirus type 6 (HPV-6) and HPV-11 genomes sampled throughout the world

Autor: N Kiviat, Shih-Yen Chan, J Kuypers, Kei Fujinaga, P Balaram, H Pfister, M S Campo, L. C. Ho, M O'Connor, P A Heinzel

Publikováno v: Journal of clinical microbiology. 33(7)

We examined the genomic diversity of human papillomavirus type 6 (HPV-6) and HPV-11 isolates from different parts of the world by comparing the nucleotide sequences of part of the long control region of three reference clones and 62 HPV-6 and 40 HPV-

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2d507aa158b32fc4c2fb5bf21d7e894
https://pubmed.ncbi.nlm.nih.gov/7665641

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