Zobrazeno 1 - 10
of 17
pro vyhledávání: '"M. S. Buchmann"'
Autor:
Gösta Eggertsen, Yousuke Seyama, Maria Olin, M S Buchmann, E Rystedt, Arnold Berstad, Ingemar Björkhem
Publikováno v:
Journal of Internal Medicine. 252:259-264
Cerebrotendinous xanthomatosis (CTX) is a hereditary disorder, which is inherited as an autosomally recessive disease, causing production of cholesterol and cholestanol xanthomas and mental retardation. The disease is caused by mutations in the gene
Publikováno v:
Allergy. 57:529-533
Background: Little is known about cockroach sensitization in Scandinavia, whereas cockroaches are implicated in allergic diseases throughout large parts of the world. In association with the Genetics of Asthma International Network (GAIN) study, we r
Publikováno v:
Journal of Lipid Research, Vol 29, Iss 2, Pp 157-164 (1988)
The bile acid precursor 7 alpha-hydroxy-4-cholesten-3-one was found to be enzymatically dehydroxylated at a slow rate by liver tissues from the rat, human, and guinea pig. The rat liver enzyme is localized in the microsomal fraction, has a pH optimum
Externí odkaz:
https://doaj.org/article/d9d4eecfef154ddd923726aa2cd70e7c
Autor:
M. J. A. G. Hamers, M. S. Buchmann, Helge Stormorken, Kjell S. Sakariassen, L. Örning, U. Ørvim, R. M. Barstad
Publikováno v:
Acta Radiologica. 37:954-961
Background: The aims of the present study were to investigate whether ionic and nonionic contrast media (CM) affect: 1) the procoagulant and fibrinolytic activities of cultured human vessel endothelium; and 2) early events of tissue-factor-induced ar
Autor:
Geir Håland, K. C. Lødrup Carlsen, Chandra Sekhar Devulapalli, Staffan Ahlstedt, Lars Söderström, M. Pettersen, M. S. Buchmann, Petter Mowinckel, M. C. Munthe Kaas, Kai-Håkon Carlsen
Publikováno v:
Allergy.
To cite this article: Lodrup Carlsen KC, Soderstrom L, Mowinckel P, Haland G, Pettersen M, Munthe Kaas MC, Devulapalli CS, Buchmann M, Ahlstedt S, Carlsen K-H. Asthma prediction in school children; the value of combined IgE-antibodies and obstructive
Publikováno v:
Europe PubMed Central
Scopus-Elsevier
Scopus-Elsevier
The mechanism and stereochemistry in connection with enzymatic conversion of cholesta-4,6-dien-3-one into cholestanol was studied. Rat and mouse liver microsomes are able to catalyze NADPH-dependent sequential saturation of the two double bonds. Evid
Autor:
Ingemar Björkhem, Jan Sjövall, T Gunasekaran, H Nazer, Peter E. Clayton, M. S. Buchmann, E. A. Kvittingen
Publikováno v:
The Journal of clinical investigation. 86(6)
Cultured fibroblasts were shown to be capable of catalyzing the conversion of 7 alpha-hydroxy-cholesterol to 7 alpha-hydroxy-4-cholesten-3-one, an important reaction in bile acid synthesis. The apparent Km was approximately 7 mumol/liter and Vmax var
Publikováno v:
Scopus-Elsevier
Biliary 7 alpha-hydroxy-4-cholesten-3-one (an intermediate in bile acid biosynthesis) may be 7 alpha-dehydroxylated in the gut and further metabolized to cholestanol (Skrede, S., and Bjorkhem, I. (1982) J. Biol. Chem. 257, 8363-8367). We have now eva
Autor:
S. O. Lie, Ingemar Björkhem, Cara East, Sverre Skrede, Scott M. Grundy, M S Buchmann, E. A. Kvittingen
Publikováno v:
Scopus-Elsevier
26-Hydroxylation of 5 beta-cholestane-3 alpha, 7 alpha, 12 alpha-triol and other C27-steroids was demonstrated in cultured skin fibroblasts from healthy individuals. Activities in skin fibroblasts were approximately 5-10% of those previously found in
Publikováno v:
Scandinavian Journal of Gastroenterology. 20:1262-1266
It was recently proposed that the increased biosynthesis of cholestanol in cerebrotendinous xanthomatosis (CTX) is due to increased activity of the delta 5-3 beta-hydroxysteroid dehydrogenase involved in bile acid biosynthesis, causing increased conv