Zobrazeno 1 - 6
of 6
pro vyhledávání: '"M. S. Alkhuseyn-Kulyaginova"'
Autor:
M. A. Dodokhova, A. V. Safronenko, I. M. Kotieva, M. S. Alkhuseyn-Kulyaginova, E. R. Milaeva, D. B. Shpakovsky, Yu. M. Makarenko, A. Yu. Terekhov, E. O. Sergeeva
Publikováno v:
Crimea Journal of Experimental and Clinical Medicine. 11:11-18
The most important task of preclinical research of promising candidates for antitumor drugs is to assess the safety of their use. The study of the cardiotoxicity of organotin compounds (OOS) dimethyltin bis (3,5-di-tert-butyl-4-hydroxy- phenylthiolat
Autor:
V. G. Trepel, A. V. Safronenko, Elena R. Milaeva, M. A. Dodokhova, Ekaterina Fedorovna Komarova, I. M. Kotieva, D. B. Shpakovskiy, M. S. Alkhuseyn-Kulyaginova
Publikováno v:
Ural Medical Journal. 20:73-77
The aim of the study was to evaluate the safety of the use of organotin compounds containing a fragment of 2,6-di-tert-butylphenol as pharmaceutical substances when administered intragastrically to Wistar outbred rats (females). Material and methods.
Autor:
D. B. Shpakovskiy, Elena R. Milaeva, V. G. Trepel, M. A. Dodokhova, M. S. Alkhuseyn–Kulyaginova, А. V. Safronenko, I. M. Kotieva
Publikováno v:
Ural Medical Journal. 20:18-23
Introduction. The aim of the study was to evaluate the effect of hybrid organotin compounds bis(3,5–di– tert–butyl–4–hydroxyphenylthiolate) dimethylol (Me3) and ((3,5–di–tert–butyl–4–hydroxyphenylthiolate) triphenylolol (Me5) on t
Autor:
Elena R. Milaeva, I. M. Kotieva, M. A. Dodokhova, D.B. Shpakovsky, T.A. Antonenko, E. V. Gantsgorn, Ekaterina Fedorovna Komarova, M. S. Alkhuseyn-Kulyaginova, A. V. Safronenko
Publikováno v:
Journal Biomed. 17:88-99
This review analyzed the literature data on the in vitro preclinical study of the cytotoxic properties of organotin compounds, as well as the main mechanisms of their action. The latter consist in interacting with SH groups of proteins, initiating ox
Autor:
Ekaterina Fedorovna Komarova, Alexander A. Shtil, A. V. Safronenko, M. S. Alkhuseyn-Kulyaginova, Dmitriy Borisovich Shpakovsky, I. M. Kotieva, Elena R. Milaeva, M. A. Dodokhova
Publikováno v:
Journal of Clinical Oncology. 39:e15054-e15054
e15054 Background: Lung cancer occupies one of the first places in the structure of oncological diseases in the world. Reducing the life expectancy of patients, as a rule, occurs as a result of metastatic complications, so the search for new antimeta
Autor:
Elena R. Milaeva, Dmitriy Borisovich Shpakovsky, Alexander A. Shtil, A. V. Safronenko, I. M. Kotieva, Ekaterina Fedorovna Komarova, M. A. Dodokhova, M. S. Alkhuseyn-Kulyaginova
Publikováno v:
Journal of Clinical Oncology. 39:e21564-e21564
e21564 Background: Melanoma is an extremely malignant tumor. The unfavorable prognosis in the treatment of patients is mainly due to aggressive metastasis of the tumor in various ways: hematogenic, lymphogenic and lymphohematogenic. Metastatic melano