Low-dose carboplatin modifies the tumor microenvironment to augment CAR T cell efficacy in human prostate cancer models

Autor: L. H. Porter, J. J. Zhu, N. L. Lister, S. G. Harrison, S. Keerthikumar, D. L. Goode, R. Quezada Urban, D. J. Byrne, A. Azad, I. Vela, M. S. Hofman, P. J. Neeson, P. K. Darcy, J. A. Trapani, R. A. Taylor, G. P. Risbridger

Publikováno v: Nature Communications, Vol 14, Iss 1, Pp 1-17 (2023)

Abstract Chimeric antigen receptor (CAR) T cells have transformed the treatment landscape for hematological malignancies. However, CAR T cells are less efficient against solid tumors, largely due to poor infiltration resulting from the immunosuppress

Externí odkaz: https://doaj.org/article/eb8dadc0a7e045c7b9cf4a1d7631aa08

Immunotherapy Vaccines for Prostate Cancer Treatment.

Autor: He, Jide¹ (AUTHOR), Wu, Jialong¹ (AUTHOR), Li, Ziang¹ (AUTHOR), Zhao, Zhenkun¹ (AUTHOR), Qiu, Lei¹ (AUTHOR), Zhu, Xuehua¹ (AUTHOR), Liu, Zenan¹ (AUTHOR), Xia, Haizhui¹ (AUTHOR), Hong, Peng¹ (AUTHOR), Yang, Jianling² (AUTHOR), Ni, Ling³ (AUTHOR) lingni@tsinghua.edu.cn, Lu, Jian^1,4 (AUTHOR) lujian@bjmu.edu.cn

Publikováno v: Cancer Medicine. Oct2024, Vol. 13 Issue 20, p1-13. 13p.

Inert Transition Metal Ion Complexes in Organic Synthesis: Protection and Activation.

Autor: Donnelly, Paul S.¹ (AUTHOR) pauld@unimelb.edu.au, Harrowfield, Jack M.² (AUTHOR) harrowfield@unistra.fr, Koutsantonis, George A.³ (AUTHOR) george.koutsantonis@uwa.edu.au, Lengkeek, Nigel A.³ (AUTHOR), Ling, Irene⁴ (AUTHOR) ireneling@monash.edu, Nealon, Gareth L.³ (AUTHOR), McInnes, Lachlan E.¹ (AUTHOR), Skelton, Brian W.³ (AUTHOR), Sobolev, Alexandre N.³ (AUTHOR) alexandre.sobolev@uwa.edu.au, White, Allan H.⁵ (AUTHOR), White, Jonathan M.¹ (AUTHOR) whitejm@unimelb.edu.au

Publikováno v: Chemistry - An Asian Journal. Sep2023, Vol. 18 Issue 18, p1-11. 11p.

Persistent luminescence nanoparticles with high intensity for colorectal cancer surgery navigation and precision resection.

Autor: Yan, Zichao, Wang, Yifei, Qiu, Minghan, Long, Kai, Zhang, Zhouyu, Sun, Mengjie, Yin, Chang, Wang, Wei, Wang, Hua-qing, Yuan, Zhi

Publikováno v: Journal of Materials Chemistry B; 9/21/2024, Vol. 12 Issue 35, p8655-8661, 7p

Recent Progress on Nanomaterial-Facilitated Electrochemical Strategies for Cancer Diagnosis.

Autor: Yuan X; State Key Laboratory of Materials-Oriented Chemical Engineering, College of Chemical Engineering, Nanjing Tech University, Nanjing, 211816, China., Lin B; State Key Laboratory of Materials-Oriented Chemical Engineering, College of Chemical Engineering, Nanjing Tech University, Nanjing, 211816, China., Liu T; State Key Laboratory of Materials-Oriented Chemical Engineering, College of Chemical Engineering, Nanjing Tech University, Nanjing, 211816, China., Zhang W; State Key Laboratory of Materials-Oriented Chemical Engineering, College of Chemical Engineering, Nanjing Tech University, Nanjing, 211816, China.; Department of Anesthesiology, Nanjing Drum Tower Hospital, The Affiliated Hospital of Nanjing University Medical School, 321 Zhongshan Road, Nanjing, 210008, China., Chu Z; State Key Laboratory of Materials-Oriented Chemical Engineering, College of Chemical Engineering, Nanjing Tech University, Nanjing, 211816, China., Gu X; Department of Anesthesiology, Nanjing Drum Tower Hospital, The Affiliated Hospital of Nanjing University Medical School, 321 Zhongshan Road, Nanjing, 210008, China., Ma Z; Department of Anesthesiology, Nanjing Drum Tower Hospital, The Affiliated Hospital of Nanjing University Medical School, 321 Zhongshan Road, Nanjing, 210008, China., Jin W; State Key Laboratory of Materials-Oriented Chemical Engineering, College of Chemical Engineering, Nanjing Tech University, Nanjing, 211816, China.

Publikováno v: Advanced healthcare materials [Adv Healthc Mater] 2023 Jun; Vol. 12 (16), pp. e2203029. Date of Electronic Publication: 2023 Feb 17.