Zobrazeno 1 - 10
of 415
pro vyhledávání: '"M. Rozencweig"'
Autor:
N. Azarnia, José Baselga, Alexey Manikhas, Vladimir Semiglazov, Clifford A. Hudis, R.H. Goldfarb, S. Forenza, M. Rozencweig, Javier Cortes, J. Matera, Mikhail Byakhov, L Roman, D. Lokanatha, Antonio Llombart
Publikováno v:
Annals of Oncology
Nonpegylated liposomal doxorubicin liposomal doxorubicin, (Myocet™; Sopherion Therapeutics, Inc Canada, and Cephalon, Europe) (NPLD; Myocet(®)) in combination with trastuzumabHerceptin(®) (Hoffmann-La Roche) has shown promising activity and cardi
Autor:
Alexey Manikhas, S. Forenza, N. Azarnia, M. Rozencweig, J. Matera, Clifford A. Hudis, Vladimir Semiglazov, J. Baselga, L Roman, Ronald H. Goldfarb
Publikováno v:
Cancer Research. 70:P6-14
Background: Myocet™ (M) is a non-pegylated liposomal doxorubicin which exhibits reduced cardiotoxicity as compared to conventional doxorubicin. A phase 1/2 non-randomized multi-site trial combining M, trastuzumab (H) and paclitaxel (T) has resulted
Publikováno v:
Harefuah. 128(3)
Autor:
N, Onetto, R, Canetta, B, Winograd, R, Catane, M, Dougan, J, Grechko, J, Burroughs, M, Rozencweig
Publikováno v:
Journal of the National Cancer Institute. Monographs. (15)
The safety profile of Taxol administered intravenously as a single agent has been established based on the experience of 655 patients. Of these patients, 253 were treated in nine phase I studies, and 402 were treated in eight disease-oriented phase I
Autor:
L P, Schacter, C, Anderson, R M, Canetta, S, Kelley, C, Nicaise, N, Onetto, M, Rozencweig, L, Smaldone, B, Winograd
Publikováno v:
Seminars in oncology. 19(6)
The discovery and development of new anticancer drugs is a complex and largely empirical process. New compounds can be discovered by screening, modification of existing compounds, rational drug design, and serendipitous basic research observations. S
Publikováno v:
Seminars in oncology. 17(6 Suppl 9)
Hormonal therapy of breast cancer is widely used and effective. Although never curative in advanced disease, significant palliation and durable remissions can be obtained with a wide variety of hormonal manipulations. Historically, surgical ablation
Publikováno v:
The Journal of Clinical Pharmacology. 18:29-34
The potency of 5 migrogram moxestrol (R 2858). 11beta-methoxy-17alpha-ethinyl-estra-1,3,5-[10]-triene-3,17-diol, administered orally, was compared to that of 25 microgram ethinyl estradiol in a double-blind crossover clinical pharmacology study of si
Autor:
E. Longeval, Marc L'Hermite, E. Van Cauter, Abraham Borkowski, Carl Muquardt, M. Rozencweig, Pierre Dor
Publikováno v:
Journal of Endocrinology. 73:235-246
The endocrine response to prolonged dexamethasone treatment was investigated in six postmenopausal women with generalized mammary carcinoma. Plasma cortisol levels decreased rapidly and became undetectable whereas significant concentrations of plasma
Autor:
A. Lieber, H.P. Morris, E. Jacobs, K. Schieweck, M.H. Cohen, E.P. Ho, A.I. Kolosov, U. Joss, G. Weber, L. Bellelli, M.M. Reddy, Roslyn Kushinsky, B.L. Strauss, V.N. Anisimov, A.L. Truant, M. Muggia, M.A. Lea, A. Furst, D.R. Webb, F.H. DeLand, J.L. Gainer, K.H. Schmidt-Ruppin, Sophia Tsang, R.P. Pugh, Maria O. Hornung, C.J. Louis, Maria Luisa Sezzi, M. Rozencweig, D.C. Stolinsky, D. Abraham, J.R. Jones, St.P.L. Leong, L. Sadoff, Y. Maruyama, G.P. Tryfiates, S.S. Legha, A.B. Okey, Maria Ardeleanu, E.T. Krementz, J.V. Hallum, W.J. Durkin, L.N. Bulovskaya, C.M. Ianicello, I. Laszlo, T. Pajak, V.M. Dilman, J.R. Bateman, J.K. Shuler, K.O. Goh, J.M. Weiner, D.D. VonHoff, F. Fodor, Doina Pop D. Popa, M. Kerekes, J.W.T. Dickerson, J. Solomon, T.K. Basu, M. Slavik, L. Schuller, D.A. Wallis
Publikováno v:
Oncology. 33:I-IV
Publikováno v:
Cancer Chemotherapy and Pharmacology. 1:83-90
The antitumor antibiotics are a heterogeneous group of antineoplastic agents which share a common origin as fermentation products of microbial cultures. This brief review of selected agents will emphasize those agents that play a major role in curren