Zobrazeno 1 - 10
of 456
pro vyhledávání: '"M. Roseman"'
Publikováno v:
Neurology International, Vol 16, Iss 4, Pp 821-832 (2024)
High blood pressure (BP) and cerebral amyloid angiopathy (CAA) are two common risk factors for intracranial hemorrhage, potentially leading to cognitive impairment. Less is known about the relationship between BP and CAA, the examination of which was
Externí odkaz:
https://doaj.org/article/de076f3354284dc7949f805a9f39bbcc
Autor:
Robert E. Turnbull, Louise Fairall, Almutasem Saleh, Emma Kelsall, Kyle L. Morris, T. J. Ragan, Christos G. Savva, Aditya Chandru, Christopher J. Millard, Olga V. Makarova, Corinne J. Smith, Alan M. Roseman, Andrew M. Fry, Shaun M. Cowley, John W. R. Schwabe
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
The MiDAC complex recruits class I histone deacetylases to chromatin but little is known about its precise structure and function. Here, the authors explore the role of MiDAC in the cell cycle and during mouse embryogenesis, and present cryoEM struct
Externí odkaz:
https://doaj.org/article/6a71d260306a424c936ce21edc133482
Autor:
Tomas Adomavicius, Margherita Guaita, Yu Zhou, Martin D. Jennings, Zakia Latif, Alan M. Roseman, Graham D. Pavitt
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-10 (2019)
During the integrated stress response, translation is modulated through the phosphorylation of translation initiation factor eIF2 and the formation of a complex with eIF2B. Here the authors present structures of the eIF2:eIF2B complex with and withou
Externí odkaz:
https://doaj.org/article/b178b1da56a2498cb1e4d2d9ec16bc26
Autor:
Luigi De Colibus, Elina Roine, Thomas S. Walter, Serban L. Ilca, Xiangxi Wang, Nan Wang, Alan M. Roseman, Dennis Bamford, Juha T. Huiskonen, David I. Stuart
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-9 (2019)
Here, the authors present the cryo-EM structure of the archaeal virus SH1 at 3.8 Å resolution and show how the major capsid proteins assemble into hetero-hexamers, providing insights into the assembly process of this and related PRD1-adeno lineage v
Externí odkaz:
https://doaj.org/article/c49688e838814e378948c888e788bdd5
Autor:
Alan R. F. Godwin, Rana Dajani, Xinyang Zhang, Jennifer Thomson, David F. Holmes, Christin S. Adamo, Gerhard Sengle, Michael J. Sherratt, Alan M. Roseman, Clair Baldock
Publikováno v:
Nature Structural & Molecular Biology. 30:608-618
Genetic mutations in fibrillin microfibrils cause serious inherited diseases, such as Marfan syndrome and Weill–Marchesani syndrome (WMS). These diseases typically show major dysregulation of tissue development and growth, particularly in skeletal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::400c67b7f71f6588859742122393a277
https://doi.org/10.1038/s41594-023-00950-8
https://doi.org/10.1038/s41594-023-00950-8
Autor:
Charles Faselis, Joel A. Nations, Charity J. Morgan, Jared Antevil, Jeffrey M. Roseman, Sijian Zhang, Gregg C. Fonarow, Helen M. Sheriff, Gregory D. Trachiotis, Richard M. Allman, Prakash Deedwania, Qing Zeng-Trietler, Daniel D. Taub, Amiya A. Ahmed, George Howard, Ali Ahmed
Publikováno v:
JAMA Oncol
ImportanceThe US Preventive Services Task Force does not recommend annual lung cancer screening with low-dose computed tomography (LDCT) for adults aged 50 to 80 years who are former smokers with 20 or more pack-years of smoking who quit 15 or more y
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d26f8664ea46828392302d5a2a63f42b
https://pubmed.ncbi.nlm.nih.gov/36048454
https://pubmed.ncbi.nlm.nih.gov/36048454
Publikováno v:
Journal of Clinical Medicine; Volume 12; Issue 11; Pages: 3807
Cerebral microinfarcts are associated with cognitive impairment and dementia. Small vessel diseases such as cerebral arteriolosclerosis and cerebral amyloid angiography (CAA) have been found to be associated with microinfarcts. Less is known about th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=multidiscipl::9788f03841659db62bde42c0c9b6ad89
Akademický článek
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In June 1854 the Grand Excursion celebrated in festive style the completion of the Chicago and Rock Island Railroad to the Mississippi River. Hundreds of dignitaries including newspaper editors and other journalists; politicians; academics, writers a
Autor:
Alan RF Godwin, Jennifer Thomson, David F Holmes, Christin S Adamo, Gerhard Sengle, Michael J Sherratt, Alan M Roseman, Clair Baldock
Genetic mutations in fibrillin microfibrils cause a range of serious inherited diseases such as Marfan syndrome (MFS) and Weill-Marchesani syndrome (WMS). These diseases typically show major dysregulation of tissue development and growth, particularl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b872a4f3960a89eb50d64c9385e52f4a
https://doi.org/10.1101/2022.08.26.505362
https://doi.org/10.1101/2022.08.26.505362