Zobrazeno 1 - 10
of 21
pro vyhledávání: '"M. Rohan Fernando"'
Publikováno v:
Genetics in Medicine Open, Vol 2, Iss , Pp 100899- (2024)
Externí odkaz:
https://doaj.org/article/03b14e78b7764f8ead29a9fa211ed7b5
Publikováno v:
PLoS ONE, Vol 13, Iss 12, p e0208508 (2018)
This study was undertaken to evaluate a novel method for stabilizing and preserving the original proportion of cell-free fetal DNA (cffDNA) in maternal blood for extended periods of time without using crosslinking agents, such as formaldehyde, which
Externí odkaz:
https://doaj.org/article/0e884f8b0ac74be5be445bd065d5a3c8
Publikováno v:
PLoS ONE, Vol 12, Iss 8, p e0183915 (2017)
Cell-free DNA (cfDNA) in blood is used as a source of genetic material for noninvasive prenatal and cancer diagnostic assays in clinical practice. Recently we have started a project for new biomarker discovery with a view to developing new noninvasiv
Externí odkaz:
https://doaj.org/article/6c38870b9cb94396a4e5aeabdfce731a
Publikováno v:
Clinica chimica acta; international journal of clinical chemistry. 483
Background Plasma cell-free DNA (cfDNA) fragment size distribution provides important information required for diagnostic assay development. We have developed and optimized droplet digital PCR (ddPCR) assays that quantify short and long DNA fragments
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8f7ff08797fa8707b605bad64ae4cae
https://pubmed.ncbi.nlm.nih.gov/29655637
https://pubmed.ncbi.nlm.nih.gov/29655637
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics. 1774:545-555
Low molecular weight protein tyrosine phosphatase (LMW-PTP) was cloned from human lens epithelial B3 cells (HLE B3) and the recombinant enzyme was purified to homogeneity. The pure enzyme reacted positively with anti-LMW-PTP antibody, displayed tyros
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8196c69a5dc47266fe76d7640ce4a3b7
https://doi.org/10.1016/j.bbapap.2007.03.001
https://doi.org/10.1016/j.bbapap.2007.03.001
Publikováno v:
Journal of Clinical Laboratory Analysis
Background Cell-free DNA (cfDNA) circulating in blood is currently used for noninvasive diagnostic and prognostic tests. Minimizing background DNA is vital for detection of low abundance cfDNA. We investigated whether a new blood collection device co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2ff0453efece2d45ba144c7dd0e40db
https://pubmed.ncbi.nlm.nih.gov/23852790
https://pubmed.ncbi.nlm.nih.gov/23852790
Publikováno v:
Clinical biochemistry. 45(16-17)
Objective To investigate whether a new blood collection device stabilizes cell-free RNA (cfRNA) in blood post-phlebotomy when compared to collection using K3EDTA tubes. Design and methods Blood samples were drawn from healthy donors into K3EDTA tubes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f3159589191556b075d501187cf0316
https://pubmed.ncbi.nlm.nih.gov/22820431
https://pubmed.ncbi.nlm.nih.gov/22820431
Autor:
Kui Yi Xing, Charles A. Kuszynski, Yin Wang, Marjorie F. Lou, M. Rohan Fernando, Ye-Shih Ho, Stefan Löfgren
Publikováno v:
Investigative ophthalmologyvisual science. 49(10)
PURPOSE. To examine the physiological function of the thioltransferase (TTase)/glutathione (GSH) system in the lens using TTase knockout mouse (TTase -/- ) lens epithelial cells (LECs) as a model. METHODS. Primary LEC cultures were obtained from wild
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::871ad5132df581b10ab243871537ac51
https://pubmed.ncbi.nlm.nih.gov/18586881
https://pubmed.ncbi.nlm.nih.gov/18586881
Thioredoxin (TRx) is known to control redox homeostasis in cells. In recent years, a specific TRx binding protein called thioredoxin binding protein-2 (TBP-2) was found in other cell types and it appeared to negatively regulate TRx bioavailability an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19f67ab5660f99f91b1242e63503fd78
https://europepmc.org/articles/PMC1994116/
https://europepmc.org/articles/PMC1994116/
Publikováno v:
Molecular vision. 12
To investigate whether mammalian thioredoxin (Trx) and thioredoxin reductase (TrxR), with or without alpha-crystallin can revive inactivated glyceraldehyde 3-phosphate dehydrogenase (GAPDH) in both the cortex and nucleus of human aged clear and catar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d2e7164b01a936cdaa12f31f4e06536a
https://pubmed.ncbi.nlm.nih.gov/17093401
https://pubmed.ncbi.nlm.nih.gov/17093401