Zobrazeno 1 - 8
of 8
pro vyhledávání: '"M. Rocio A. Carrera"'
Autor:
Kim D. Janda, Jenny M. Mee, Gunnar F. Kaufmann, M. Rocio A. Carrera, Michael M. Meijler, George F. Koob
Publikováno v:
Proceedings of the National Academy of Sciences. 101:10416-10421
Cocaine addiction continues to be a major health and social problem in the United States and other countries. Currently used pharmacological agents for treating cocaine abuse have proved inadequate, leaving few treatment options. An alternative is to
Publikováno v:
Proceedings of the National Academy of Sciences. 97:6202-6206
The efficacy of active immunization with the cocaine immunogen GNC-keyhole limpet hemocyanin (KLH) in preventing cocaine self-administration reinstatement was assessed in rats. An animal model of relapse was used where rats were trained to self-admin
Autor:
Friedbert Weiss, George F. Koob, M. Rocio A. Carrera, Miguel Navarro, Fernando Rodríguez de Fonseca
Publikováno v:
Science. 276:2050-2054
Corticotropin-releasing factor (CRF) has been implicated in the mediation of the stress-like and negative affective consequences of withdrawal from drugs of abuse, such as alcohol, cocaine, and opiates. This study sought to determine whether brain CR
Autor:
Fernando Rodríguez de Fonseca, M. Rocio A. Carrera, Miguel Navarro, George F. Koob, Jose Manuel Trigo, Ignacio del Arco
Publikováno v:
European Journal of Pharmacology. 501:235-237
Functionality of the endogenous cannabinoid system undergoes relevant changes in reward-related brain areas in animal models of opiate addiction. By using a limited access heroin self-administration paradigm we show that cannabinoid CB(1) receptor an
Publikováno v:
Pharmacology, biochemistry, and behavior. 81(4)
The illicit use of cocaine continues in epidemic proportions and treatment for cocaine overdose remains elusive. Current protein-based technology offers a new therapeutic venue by which antibodies bind the drug in the blood stream, inactivating its t
Publikováno v:
Bioorganicmedicinal chemistry. 12(19)
Cocaine abuse continues to be prevalent and effective therapies for cocaine craving and addiction remain elusive. In the last decade immunopharmacotherapy has been proposed as a promising means to alleviate this illness. By using the organism's natur
Autor:
Shigeki Isomura, Peter Wirsching, Kim D. Janda, Timothy Z. Hoffman, George F. Koob, M. Rocio A. Carrera, Jon A. Ashley
Publikováno v:
Bioorganicmedicinal chemistry. 12(3)
Despite the enormous health risks, people continue to smoke and use tobacco primarily as a result of nicotine addiction. As part of our immunopharmacotherapy research, the effects of active and passive immunizations on acute nicotine-induced locomoto
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