Zobrazeno 1 - 10
of 45
pro vyhledávání: '"M. Reza Nejadnik"'
Autor:
Mara Leone, Bart H. van Oorschot, M. Reza Nejadnik, Andrea Bocchino, Matteo Rosato, Gideon Kersten, Conor O’Mahony, Joke Bouwstra, Koen van der Maaden
Publikováno v:
Pharmaceutics, Vol 10, Iss 4, p 211 (2018)
Microneedle technologies have been developed for dermal drug and vaccine delivery, including hollow-, solid-, coated-, and dissolving microneedles. Microneedles have been made in many different geometries and of many different materials, all of which
Externí odkaz:
https://doaj.org/article/4b3ee45e421447f99330602082fda93f
Autor:
Annette Medina Morales, Alavattam Sreedhara, Jakob Buecheler, Sebastian Brosig, Danny Chou, Twinkle Christian, Tapan Das, Isabella de Jong, Jonas Fast, Bharat Jagannathan, Ehab M. Moussa, M. Reza Nejadnik, Indira Prajapati, Allison Radwick, Yusra Rahman, Shubhadra Singh
Publikováno v:
The AAPS journal. 25(1)
A survey performed by the AAPS Drug Product Handling community revealed a general, mostly consensus, approach to the strategy for the selection of surfactant type and level for biopharmaceutical products. Discussing and building on the survey results
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::934367107d35825c8e0bc87085b49b01
https://pubmed.ncbi.nlm.nih.gov/36471030
https://pubmed.ncbi.nlm.nih.gov/36471030
Autor:
Stefan Romeijn, Wim Jiskoot, Juha Mönkäre, Conor O'Mahony, Marjolein I. Priester, Mara Leone, Gideon F.A. Kersten, Joke A. Bouwstra, M. Reza Nejadnik
Publikováno v:
European Journal of Pharmaceutics and Biopharmaceutics
European Journal of Pharmaceutics and Biopharmaceutics, 134, 49-59
European Journal of Pharmaceutics and Biopharmaceutics, 134, 49-59
The purpose of this study was to optimize the manufacturing of dissolving microneedles (dMNs) and to increase the antigen loading in dMNs to investigate the effect on their physicochemical properties. To achieve this, a novel single-array wells polyd
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91946b595803ee4ff305ef89837dc40c
https://doi.org/10.1016/j.ejpb.2018.11.013
https://doi.org/10.1016/j.ejpb.2018.11.013
Autor:
Daan J.A. Crommelin, Christian Schöneich, Theodore W. Randolph, John F. Carpenter, David B. Volkin, M. Reza Nejadnik, Wim Jiskoot
Publikováno v:
Journal of Pharmaceutical Sciences
Journal of Pharmaceutical Sciences, 107(8), 2013-2019
Journal of Pharmaceutical Sciences, 107(8), 2013-2019
The safety and efficacy of protein pharmaceuticals depend not only on biological activity but also on purity levels. Impurities may be process related because of limitations in manufacturing or product related because of protein degradation occurring
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e1b684ba940e51a42616ea8f38ed557
https://doi.org/10.1016/j.xphs.2018.04.005
https://doi.org/10.1016/j.xphs.2018.04.005
Autor:
Juha Mönkäre, Alexander Kros, Wim Jiskoot, Guangsheng Du, Koen van der Maaden, Nico A. J. M. Sommerdijk, Paul H. H. Bomans, M. Reza Nejadnik, Bram Slütter, Joke A. Bouwstra, Jing Tu
Publikováno v:
Pharmaceutical Research, 34(8), 1693-1706. Springer
Pharmaceutical Research, 34(8), 1693-1706
Pharmaceutical Research
Pharmaceutical Research, 34(8), 1693-1706
Pharmaceutical Research
Purpose To develop a new intradermal antigen delivery system by coating microneedle arrays with lipid bilayer-coated, antigen-loaded mesoporous silica nanoparticles (LB-MSN-OVA). Methods Synthesis of MSNs with 10-nm pores was performed and the nanopa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6fc2d152efe3645f75da27bdff9c4dac
https://doi.org/10.1007/s11095-017-2177-4
https://doi.org/10.1007/s11095-017-2177-4
Autor:
Christian Rischel, Dorrit Baunsgaard, A. Henriksen, M. Reza Nejadnik, Wim Jiskoot, Xinsheng Tian
Publikováno v:
Journal of pharmaceutical sciences
Journal of pharmaceutical sciences, 105(11), 3366–3375
Journal of pharmaceutical sciences, 105(11), 3366–3375
Nanoparticle tracking analysis (NTA) has attracted great interest for application in the field of submicron particle characterization for biopharmaceuticals. It has the virtue of direct sample visualization and particle-by-particle tracking, but the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bcd2c15eb6d0b1aff8a421fe863d8272
https://doi.org/10.1016/j.xphs.2016.08.009
https://doi.org/10.1016/j.xphs.2016.08.009
Autor:
Wim Jiskoot, Guangsheng Du, Juha Mönkäre, Stefan Romeijn, M. Reza Nejadnik, Eveline E.M. van Kampen, Maria Pontier, Bram Slütter, Mara Leone, Joke A. Bouwstra, Conor O'Mahony
Publikováno v:
European Journal of Pharmaceutics and Biopharmaceutics, 129, 111-121
European Journal of Pharmaceutics and Biopharmaceutics
European Journal of Pharmaceutics and Biopharmaceutics
Skin is an attractive but also very challenging immunisation site for particulate subunit vaccines. The aim of this study was to develop hyaluronan (HA)-based dissolving microneedles (MNs) loaded with PLGA nanoparticles (NPs) co-encapsulating ovalbum
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c28b0b2bbbb62358998fb768b1ec887b
https://hdl.handle.net/10468/8664
https://hdl.handle.net/10468/8664
Autor:
Ahmad S. Sediq, M. Reza Nejadnik, Hayley A. Every, Geert-Jan Witkamp, Miao Yu, Wim Jiskoot, Shiduo Zhang
Publikováno v:
Journal of Supercritical Fluids, 141, 49-59
Journal of Supercritical Fluids
Journal of Supercritical Fluids
The aim of this study was to develop a supercritical carbon dioxide (scCO2) spray process to coat solid protein particles with a hydrophilic polymer. The final purpose is to manufacture drug particles exhibiting controlled release behaviour in patien
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77afef95b479cc9fe188ef1e0e6e419b
http://hdl.handle.net/1887/73415
http://hdl.handle.net/1887/73415
Autor:
Wim Jiskoot, Jelte Meulenaar, M. Reza Nejadnik, R. Verrijk, Stephan K.D. Waasdorp, Ahmad S. Sediq, Miranda M. C. van Beers
The release of drugs from poly(lactic-co-glycolic acid) (PLGA) microparticles depends to a large extent on the porosity of the particles. Therefore, porosity determination of PLGA microparticles is extremely important during pharmaceutical product de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::128f2e99327f9259b92f4527f0b38f14
http://hdl.handle.net/1887/3202254
http://hdl.handle.net/1887/3202254
Publikováno v:
PHARMACEUTICAL RESEARCH, 34(6), 1152-1170
PHARMACEUTICAL RESEARCH
Pharmaceutical Research
PHARMACEUTICAL RESEARCH
Pharmaceutical Research
Bone morphogenetic proteins (BMPs) are responsible for bone formation during embryogenesis and bone regeneration and remodeling. The osteoinductive action of BMPs, especially BMP-2 and BMP-7, has led to their use in a range of insurmountable treatmen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a75e7533554e54df502657edc7842aea
http://hdl.handle.net/1887/54672
http://hdl.handle.net/1887/54672