Aging selectively dampens oscillation of lipid abundance in white and brown adipose tissue

Autor: Ntsiki M. Held, M. Renate Buijink, Hyung L. Elfrink, Sander Kooijman, Georges E. Janssens, Angela C. M. Luyf, Mia L. Pras-Raves, Frédéric M. Vaz, Stephan Michel, Riekelt H. Houtkooper, Michel van Weeghel

Publikováno v: Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)

Abstract Lipid metabolism is under the control of the circadian system and circadian dysregulation has been linked to obesity and dyslipidemia. These factors and outcomes have also been associated to, or affected by, the process of aging. Here, we in

Externí odkaz: https://doaj.org/article/9c02010f9abc4c868131db2f81cf7e9b

Aging selectively dampens oscillation of lipid abundance in white and brown adipose tissue

Autor: Sander Kooijman, Ntsiki M. Held, M. Renate Buijink, Michel van Weeghel, Angela C. M. Luyf, Frédéric M. Vaz, Georges E. Janssens, Riekelt H. Houtkooper, Mia L. Pras-Raves, Hyung L. Elfrink, Stephan Michel

Publikováno v: Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Scientific Reports, 11(1). NATURE RESEARCH
Scientific Reports
Scientific reports, 11(1):5932. Nature Publishing Group

Lipid metabolism is under the control of the circadian system and circadian dysregulation has been linked to obesity and dyslipidemia. These factors and outcomes have also been associated to, or affected by, the process of aging. Here, we investigate

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1de0bfda10297052e33c8853a791800c
http://www.scopus.com/inward/record.url?scp=85102568462&partnerID=8YFLogxK

Aging affects the capacity of photoperiodic adaptation downstream from the central molecular clock

Autor: Jos H. T. Rohling, Assaf Almog, Johanna H. Meijer, Anneke H. O. Olde Engberink, M. Renate Buijink, Stephan Michel, Charlotte B. Wit

Publikováno v: Journal of Biological Rhythms, 35(2), 167-179. SAGE PUBLICATIONS INC
Journal of Biological Rhythms

Aging impairs circadian clock function, leading to disrupted sleep-wake patterns and a reduced capability to adapt to changes in environmental light conditions. This makes shift work or the changing of time zones challenging for the elderly and, impo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f0cab3613902c35f110ceafca8159ab1
https://hdl.handle.net/1887/3182940

The influence of neuronal electrical activity on the mammalian central clock metabolome

Autor: Thomas Hankemeier, Stephan Michel, Michel van Weeghel, Jos H. T. Rohling, Johanna H. Meijer, M. Can Gulersonmez, M. Renate Buijink, Amy C. Harms

Publikováno v: Metabolomics, 14(10)
Metabolomics
Metabolomics, 14, 122

Introduction Most organisms display circadian rhythms in physiology and behaviour. In mammals, these rhythms are orchestrated by the suprachiasmatic nucleus (SCN). Recently, several metabolites have emerged as important regulators of circadian timeke

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5de6b318a7553f74f7e97b7a886f5fd0
https://pubmed.ncbi.nlm.nih.gov/30830420

Evidence for Weakened Intercellular Coupling in the Mammalian Circadian Clock under Long Photoperiod

Autor: Diego Garlaschelli, Anneke H. O. Olde Engberink, Johanna H. Meijer, Charlotte B. Wit, Ori Roethler, Jos H. T. Rohling, M. Renate Buijink, Assaf Almog, Stephan Michel

Publikováno v: PLoS ONE, 11(12), e0168954
PLoS ONE
PLoS ONE, Vol 11, Iss 12, p e0168954 (2016)
PLoS ONE, 11(12)

For animals living in temperate latitudes, seasonal changes in day length are an important cue for adaptations of their physiology and behavior to the altered environmental conditions. The suprachiasmatic nucleus (SCN) is known as the central circadi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e10a243b79dec85a26d13288bea159a
https://hdl.handle.net/1887/114549